Results 61 to 70 of about 109,064 (360)
CNS Oncology, 2016 Anaplastic astrocytoma (AA) is a diffusely infiltrating, malignant, astrocytic, primary brain tumor. AA is currently defined by histology although future classification schemes will include molecular alterations. AA can be separated into subgroups, which share similar molecular profiles, age at diagnosis and median survival, based on 1p/19q co-deletion
Sean A, Grimm, Marc C, Chamberlain
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Feasibility of Photofrin II as a radiosensitizing agent in solid tumors - Preliminary results [PDF]
, 2006 Background: Photofrin II has been demonstrated to serve as a specific and selective radiosensitizing agent in in vitro and in vivo tumor models. We aimed to investigate the feasibility of a clinical application of Photofrin II.
Byrne CJ +22 more
core +1 more source
RZiMM-scRNA: A regularized zero-inflated mixture model framework for single-cell RNA-seq data [PDF]
arXiv, 2021 Applications of single-cell RNA sequencing in various biomedical research areas have been blooming. This new technology provides unprecedented opportunities to study disease heterogeneity at the cellular level. However, unique characteristics of scRNA-seq data, including large dimensionality, high dropout rates, and possibly batch effects, bring great ...
arxiv
Archives of Otolaryngology - Head and Neck Surgery, 1956 To the generic group of the gliomas belong the tumors designated astrocytomas, and, according to Ewing, * these neoplasias are, in general, cerebral or cerebellar tumors of slow growth, composed principally of adult glial cells. The astrocytomas have a special structure and are relatively acellular and scarcely vascularized.
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EZH2, HIF-1, and their inhibitors: An overview on pediatric cancers [PDF]
, 2018 During the past decades, several discoveries have established the role of epigenetic modifications and cellularmicroenvironment in tumor growth and progression. One of the main representatives concerning epigenetic modification is the polycomb group (PcG)
Antonello Mai +6 more
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SAGE Open Medical Case Reports, 2018 Optic nerve pilocytic astrocytoma is an uncommon but well-known entity; however, intraorbital ancient pilocytic astrocytoma of the optic nerve is extremely rarely reported.
Haesu Lee Motoyama +4 more
doaj +1 more source
Molecular Oncology, EarlyView.A DIA‐MS‐based proteomics analysis of serum samples from GB patients and healthy controls showed that high levels of IL1R2 and low levels of CRTAC1 and HRG in serum are associated with poor survival outcomes for GB patients. These circulating proteins could serve as biomarkers for the prediction of outcome in patients with GB.
Anne Clavreul +11 more
wiley +1 more source
Identification of transcriptional regulatory networks specific to pilocytic astrocytoma. [PDF]
, 2011 BackgroundPilocytic Astrocytomas (PAs) are common low-grade central nervous system malignancies for which few recurrent and specific genetic alterations have been identified.
Deshmukh, Hrishikesh +8 more
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FEBS Open Bio, EarlyView.Cerebral organoids were employed as a novel model to explore the neurotoxicity of soman. Soman inhibited acetylcholinesterase activity, increased cell apoptosis and upregulated endoplasmic reticulum (ER) stress markers glucose‐regulated protein 78 (GRP78), activating transcription factor 6 (ATF6) and C/EBP homologous protein (CHOP).
Yue Wei +7 more
wiley +1 more source
Molecularly defined diffuse leptomeningeal glioneuronal tumor (DLGNT) comprises two subgroups with distinct clinical and genetic features [PDF]
, 2018 Diffuse leptomeningeal glioneuronal tumors (DLGNT) represent rare CNS neoplasms which have been included in the 2016 update of the WHO classification. The wide spectrum of histopathological and radiological features can make this enigmatic tumor entity ...
Brandner, Sebastian +34 more
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