Results 71 to 80 of about 109,064 (360)

Identification of 9 serum microRNAs as potential noninvasive biomarkers of human astrocytoma.

Neuro-Oncology, 2015
BACKGROUND Circulating microRNAs (miRNAs) are emerging as promising biomarkers for human cancer. In the current study, we investigated the potential use of serum miRNAs as biomarkers for diagnosis and prognosis in a cohort of Chinese astrocytoma patients.
F. Zhi, N. Shao, Rong Wang, Danni Deng, Lian Xue, Qiang Wang, Yi Zhang, Yi-ruing Shi, X. Xia, Suinuan Wang, Q. Lan, Yilin Yang   +11 more
semanticscholar   +1 more source

Neurotoxic amyloid β‐peptide and tau produce cytokine‐like effects on PMCA in glioblastoma cell lines, enhancing its activity and isoforms expression

FEBS Open Bio, EarlyView.
Two biomarkers of Alzheimer's disease, amyloid β‐peptide (Aβ) and tau, induce the transformation of U‐251 and other glioblastoma cell lines into neurotoxic A1‐like reactive astrocytes. This transformation is produced by cytokines and is followed by upregulation of PMCA activity and isoform expression, and is closely associated with inflammation, as ...
María Berrocal, Alberto Alvarez‐Barrientos, Ana M. Mata   +2 more
wiley   +1 more source

Everolimus for subependymal giant cell astrocytoma: 5‐year final analysis

Annals of Neurology, 2015
To analyze the cumulative efficacy and safety of everolimus in treating subependymal giant cell astrocytomas (SEGA) associated with tuberous sclerosis complex (TSC) from an open‐label phase II study (NCT00411619).
D. Franz, K. Agricola, M. Mays, C. Tudor, Marguerite M. Care, K. Holland-Bouley, N. Berkowitz, S. Miao, S. Peyrard, D. Krueger   +9 more
semanticscholar   +1 more source

An Analysis for IDH‐Mutant Grade 4 Astrocytoma Based on WHO CNS 5: Implication of Clinical Practice

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Purpose There is ongoing debate regarding the therapeutic approach and prognosis for IDH‐mutant grade 4 astrocytoma, a newly defined subtype of diffuse glioma in the 2021 WHO classification system for central nervous system tumors (WHO CNS 5). The aim of this study was to explore the clinical outcome and prognosticators for newly diagnosed IDH‐
Xianxin Qiu, Liping Liang, Lingchao Chen, Pengjie Hong, Wanzun Lin, Jiabing Liu, Zhirui Zhou, Wenjia Zhu, Tianqi Wu, Mingyuan Pan, Yihua Zhong, Jing Gao, Zhiyong Qin, Yang Wang   +13 more
wiley   +1 more source

GNAO1 encephalopathy: broadening the phenotype and evaluating treatment and outcome [PDF]

, 2017
OBJECTIVE: To describe better the motor phenotype, molecular genetic features, and clinical course of GNAO1-related disease. METHODS: We reviewed clinical information, video recordings, and neuroimaging of a newly identified cohort of 7 patients ...
Bianchini, C, Carss, Kj, Dale, Rc, Danti, FEDERICA RACHELE, Galosi, Serena, Guerrini, R. 1., Kurian, Ma, Leuzzi, Vincenzo, Mahant, N, Mcshane, T, Mctague, A, Mohammad, Ss, Montomoli, M, Ng, J, Parrini, E, Raymond, Fl, Romani, M, Samanta, R, Shah, U, Vadlamani, G, Valente, Em   +20 more
core   +3 more sources

MicroRNA-542-3p Suppresses Tumor Cell Invasion via Targeting AKT Pathway in Human Astrocytoma*

Journal of Biological Chemistry, 2015
Background: MicroRNAs play important roles in regulating AKT pathway. Results: miR-542-3p suppresses glioblastoma cell invasion through directly inhibiting AKT1, ILK, and PIK3R1.
Junchao Cai, Jingjing Zhao, Nu Zhang, Xiaonan Xu, Rong-Gang Li, Yang Yi, Lishan Fang, Le Zhang, Mengfeng Li, Jueheng Wu, Heng Zhang   +10 more
semanticscholar   +1 more source

Engineered Tissue Models to Decode Host–Microbiota Interactions

Advanced Science, EarlyView.
Host–Microbiota interactions in the human body. Created in BioRender. Ghezzi, C. (2025) https://BioRender.com/ihivskg. Abstract A mutualistic co‐evolution exists between the host and its associated microbiota in the human body. Bacteria establish ecological niches in various tissues of the body, locally influencing their physiology and functions, but ...
Miryam Adelfio, Grace E. Callen, Xuesong He, Bruce J. Paster, Hatice Hasturk, Chiara E. Ghezzi   +5 more
wiley   +1 more source

Clinicopathological characteristics of circumscribed high-grade astrocytomas with an unusual combination of BRAF V600E, ATRX, and CDKN2A/B alternations. [PDF]

, 2019
学位記番号 ...
Murakami, Chiaki, ムラカミ, チアキ, 村上, 千明   +2 more
core  

Intramedullary gangliogliomas: histopathologic and molecular features of 25 cases [PDF]

, 2016
Gangliogliomas are uncommon glioneuronal tumors, which usually arise in the cerebral hemispheres and occasionally in the brain stem. Gangliogliomas occurring in the spinal cord are extremely rare. In this study, we analyzed the clinical, histopathologic,
ANTONELLI, MANILA, Dreschmann, Verena, Dörner, Evelyn, Gessi, Marco, GIANGASPERO, FELICE, Gnekow, Astrid, Pietsch, Torsten, Waha, Andreas   +7 more
core   +1 more source

Pilocytic astrocytomas [PDF]

, 2016
Pilocytic astrocytoma (PA) is the most common pediatric brain tumor in children. PAs are a distinct histologic and biologic subset of glioma that have a slow growth rate and may even spontaneously regress. These tumors tend to arise in the cerebellum and chiasmatic/hypothalamic region, but can also occur in other regions of the central nervous system ...
Roger J. Packer, Didier Frappaz, Miriam Bornhorst   +2 more
openaire   +3 more sources