Results 311 to 320 of about 456,445 (341)
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Asymmetric Synthesis of (+)-Hypusine
Organic Letters, 2001Wittig reaction of (triphenylphosphoranylidene)acetonitrile with the lactone carbonyl of (5R,6S)-4-(benzyloxycarbonyl)-5,6-diphenyl-2,3,5,6-tetrahydro-4H-1,4-oxazin-2-one (3) and subsequent reduction generates morpholinylethylamine dihydrochloride (5) in quantitative yield and with excellent diastereoselectivity.
R P, Jain +3 more
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1996
Abstract This book covers a wide range of reactions which are of importance in the asymmetric synthesis of organic compounds. The principles of asymmetric additions to carbonyls, enolate alkylation, aldol reactions, additions to C-C double bonds, reduction and oxidation, rearrangements, and hydrolysis/ esterification reactions are ...
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Abstract This book covers a wide range of reactions which are of importance in the asymmetric synthesis of organic compounds. The principles of asymmetric additions to carbonyls, enolate alkylation, aldol reactions, additions to C-C double bonds, reduction and oxidation, rearrangements, and hydrolysis/ esterification reactions are ...
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2012
This chapter focuses on asymmetric synthesis. It begins by discussing chirality. A laboratory synthesis of a chiral compound from achiral or racemic starting materials alone always gives a racemic mixture of enantiomers. If we want to make just one enantiomer, we have to use a starting material or reagent which is also just one enantiomer.
Jonathan Clayden +2 more
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This chapter focuses on asymmetric synthesis. It begins by discussing chirality. A laboratory synthesis of a chiral compound from achiral or racemic starting materials alone always gives a racemic mixture of enantiomers. If we want to make just one enantiomer, we have to use a starting material or reagent which is also just one enantiomer.
Jonathan Clayden +2 more
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Asymmetric Synthesis of (‐)‐Acaterin.
ChemInform, 2003The asymmetric synthesis of (−)-acaterin, an inhibitor of acyl-CoA cholesterol acyl transferase has been achieved starting from the commercially available starting materials, octan-1-ol and methyl (R)-lactate. The key steps are a Sharpless asymmetric dihydroxylation and a Wittig olefination.
Subba Rao V. Kandula, Pradeep Kumar
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Asymmetric Synthesis of (+)‐Cardiobutanolide.
ChemInform, 2006AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Ashish Garg +2 more
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Asymmetric Synthesis of (−)-Swainsonine
The Journal of Organic Chemistry, 2009We report a new asymmetric synthetic method for (-)-swainsonine utilizing a chiral oxazoline precursor. The key features in this strategy are the diastereoselective oxazoline formation reaction catalyzed by palladium(0), diasteroselective dihydroxylation, and the stereocontrolled allylation reaction with TiCl(4).
Yong-Shou, Tian +5 more
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Asymmetric Synthesis Using Ketenes
ChemInform, 2003AbstractFor Abstract see ChemInform Abstract in Full Text.
Robert K. Orr, Michael A. Calter
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Asymmetric Synthesis of (+)-Negamycin
The Journal of Organic Chemistry, 2002An asymmetric synthesis of the antibiotic (+)-negamycin (1) has been achieved, starting from commercially available (5R,6S)-4-(benzyloxycarbonyl)-5,6-diphenyl-2,3,5,6-tetrahydro-4H-1,4-oxazin-2-one (2). The synthesis involved the stabilized Wittig olefination of the lactone carbonyl group of 2 and subsequent asymmetric hydrogenation to generate the ...
Rajendra P, Jain, Robert M, Williams
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Asymmetric Synthesis of Hydroxyphosphonates
ChemInform, 2005AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
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