Results 81 to 90 of about 1,165,955 (283)

Low Energy Leptogenesis in Left-Right Symmetric Models [PDF]

open access: yes, 1994
We propose a new mechanism for baryogenesis. We study the effective potential of left-right extension of the standard model and show that there can be a first order phase transition at the left-right symmetry breaking and hence $(B-L)$ symmetry breaking ...
't Hooft   +48 more
core   +3 more sources

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

Is the ridge formed by aligned jet propagation and medium flow? [PDF]

open access: yes, 2009
Motivated by the recent observation that the ridge decreases with trigger particle angle ($\phi_s$) relative to the event plane, it is theorized that the ridge is formed by interplay between jet propagation and medium flow.
Adams   +9 more
core   +1 more source

Redox regulation meets metabolism: targeting PRDX2 to prevent hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
PRDX2 acts as a central redox hub linking metabolic dysfunction‐associated steatohepatitis (MASH) to hepatocellular carcinoma (HCC). In normal hepatocytes, PRDX2 maintains redox balance and metabolic homeostasis under oxidative stress. In contrast, during malignant transformation, PRDX2 promotes oncogenic signaling, stemness, and tumor initiation ...
Naroa Goikoetxea‐Usandizaga   +2 more
wiley   +1 more source

WI e+e- Collisions at the SLC- [PDF]

open access: yes
representing the SLD ...
The Left-right Asymmetry
core  

Aversive cues fail to activate fos expression in the asymmetric olfactory-habenula pathway of zebrafish

open access: yesFrontiers in Neural Circuits, 2013
The dorsal habenular nuclei of the zebrafish epithalamus have become a valuable model for studying the development of left-right (L-R) asymmetry and its function in the vertebrate brain.
Tagide N. Decarvalho   +5 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Experimental tests on the lifetime Asymmetry

open access: yes, 2011
The experimental test problem of the left-right polarization-dependent lifetime asymmetry is discussed. It shows that the existing experiments cannot demonstrate the lifetime asymmetry to be right or wrong after analyzing the measurements on the neutron,
Abreu P.   +6 more
core   +1 more source

Home - About - Disclaimer - Privacy