Results 51 to 60 of about 189,792 (145)

The association of gout flare resolution with physical activity and sleep: a prospective remote‐monitoring study

Arthritis Care &Research, Accepted Article.
Objectives This study aimed to determine whether gout flare resolution is associated with physical activity and sleep. These findings were intended to inform the future development of a definition for flare resolution. Methods Data from 81 participants with gout who experienced >1 flare during a 6‐month prospective observational study were included ...
Sarah Stewart, Boston Girven, Mia Clarke, Irene Zeng, Angelo Gaffo, Lisa K Stamp, N Lawrence Edwards, David Rice, Tania Ka'ai, Karl Rudolph, Julie Collis, Nicola Kayes, Nicola Dalbeth   +12 more
wiley   +1 more source

Comorbidity in gout and hyperuricemia: prevalence, causes, prospects of urate lowering therapy [PDF]

Терапевтический архив, 2019
Nowadays, there is increased interest in the connection of gout and asymptomatic hyperuricemia with comorbid conditions such as diabetes mellitus, cardiovascular diseases, hypertension, chronic kidney disease and other.
M S Eliseev, A M Novikova
doaj   +1 more source

The GPX3‐VCAM1 Axis Gates Pro‐Fibrotic Tubule Cell Fate in Hyperuricemic Nephropathy

Advanced Science, EarlyView.
Hyperuricemia induces NLRP3 inflammasome signaling activation and downregulation of GPX3 in proximal tubular epithelial cells, leading to oxidative stress–driven VCAM1 upregulation, emergence of pro‐fibrotic proximal tubule cells, macrophage recruitment, and renal fibrosis.
Yunfei Qi, Qiang Zhao, Yue Lve, Yaming Yuan, Tingting Zhou, Yue Yuan, Dexi Wu, Yifan Tang, Yan Liu, Zhigang Li, Chunping Jiang, Qiurong Ding   +11 more
wiley   +1 more source

Ultrasound Findings in Symptomatic HADD of the Hand and Wrist. A Case Series of 37 Patients

Journal of Clinical Ultrasound, EarlyView.
Ultrasound enables accurate diagnosis of hydroxyapatite deposition disease of the hand and wrist in patients with acute, non‐traumatic pain, typically in middle‐aged women. Characteristic calcifications, often in the resorptive phase, support diagnosis, while radiography may confirm findings without the need for advanced imaging.
Marco Becciolini, Riccardo Picasso, Antonio Corvino, Federico Zaottini   +3 more
wiley   +1 more source

Significance of asymptomatic hyperuricemia in ankylosing spondylitis

Современная ревматология, 2021
Over the past decades, there has been an increase in the incidence of asymptomatic hyperuricemia (AHU), which includes an increased level (>360 μmol/L) of uric acid (UA) in the blood serum of patients with no clinical manifestations of gout.
R. M. Balabanova, E. V. Ilyinykh, M. V. Podryadnova, S. I. Glukhova, M. M. Urumova   +4 more
doaj   +1 more source

Vascular drivers of cerebrospinal fluid movement and enlarged perivascular spaces

Alzheimer's &Dementia, Volume 22, Issue 10, October 2026.
Abstract Perivascular spaces (PVSs) facilitate cerebrospinal fluid flow and waste clearance, which are critical for maintaining brain homeostasis. Enlarged PVSs (ePVSs) are an emerging marker of cerebral small vessel disease and are implicated in protein accumulation, neurodegeneration, and cognitive decline.
James D. LeFevre, Yukti Vyas, Angela L. Jefferson   +2 more
wiley   +1 more source

Uric acid-lowering effect of dotinurad, a novel selective urate reabsorption inhibitor, in hypertensive patients with gout or asymptomatic hyperuricemia: a pooled analysis of individual participant data in phase II and III trials

Clinical and Experimental Hypertension, 2021
Background: Hyperuricemia is a risk factor for the development of hypertension and is comorbid in many hypertensive patients. According to Japanese hypertension management guidelines published in 2019, a target serum uric acid level of ≤6.0 mg/dL is ...
Toshinari Takahashi, Takanobu Beppu, Yuji Hidaka, Tatsuo Hosoya   +3 more
doaj   +1 more source

Inflammatory Bowel Disease Is Associated With an Increased Risk of End‐Stage Renal Disease: A Population‐Based Cohort Study

Alimentary Pharmacology &Therapeutics, Volume 64, Issue 8, Page 1110-1122, October 2026.
In a retrospective population‐based cohort study using the University of Manitoba IBD Epidemiology Database, persons with IBD have an increased risk of ESRD by nearly 50%, with CD showing greater risk than UC. Bowel surgery, allopurinol use and oral steroid therapy are important predictors, emphasising the necessity of careful renal monitoring in IBD ...
Onuma Sattayalertyanyong, Zoann Nugent, Bryce Barr, Keevin N. Bernstein, Charles N. Bernstein   +4 more
wiley   +1 more source

Rhabdomyolysis Associated With Heated Massage Therapy in a Patient Without Major Trauma: A Case Report

Clinical Case Reports, Volume 14, Issue 9, September 2026.
ABSTRACT A 29‐year‐old professional dancer developed rhabdomyolysis after distal radial fracture fixation complicated by laryngospasm, negative pressure pulmonary oedema, suxamethonium use, and ICU admission. Creatine phosphokinase (CPK) peaked at 36,429 U/L with dark urine and hyperkalaemia.
Ashani Ratnayake, Sayomi Warnakula, Yasitha Handapangoda, Udara Rathnayake, Lasanthika Athapaththu, Sanduni Rupasinghe   +5 more
wiley   +1 more source

Serum Albumin and Uric Acid Levels Among Hypertensive Patients in Northwest Ethiopia: A Comparative Cross‐Sectional Study

Health Science Reports, Volume 9, Issue 9, September 2026.
ABSTRACT Background and Aims Hypertension is a long‐term condition marked by consistently high arterial blood pressure. Hypertensive patients often experience altered serum albumin and uric acid, attributed to factors like inflammation, kidney damage, and the activation of the renin angiotensin aldosterone system.
Arega Zenaw, Belete Biadgo, Getnet Fetene, Biruktawit Abebe Assmamaw, Hana Yohanns, Adane Derso, Sintayehu Admas, Abrham Azanaw, Lyusira Marelign, Yonatan Kindie, Abebe Yenesew   +10 more
wiley   +1 more source