Results 61 to 70 of about 189,792 (145)

Beyond Traditional Screening: The Future of Heart Failure Detection With Biomarkers and AI

iNew Medicine, Volume 2, Issue 3, September 2026.
Advancing HF Screening: Integrating Technology and Risk Factors Across Eras. This diagram provides a comprehensive review of the historical developments and projected trends of heart failure (HF) screening methodologies, with the prevalent risk factors for HF depicted at the base.
Xiaofeng Fang, Yinbo Xu, Yiting Zhao, Liuyi Li, Zhengyi Cheng, Zhongqi Zhang, Yuhang Luo, Qiaoling Liu, Chen Gong, Shichun Shen   +9 more
wiley   +1 more source

Comparative Effects of Angiotensin Receptor Blockers on Blood Pressure and Serum Urate in Patients With Hypertension and Hyperuricaemia: A Systematic Review and Network Meta‐Analysis

Medicine Bulletin, Volume 2, Issue 4, Page 459-475, September 2026.
Allisartan ranked best for serum urate reduction and showed favourable blood pressure control, whereas losartan also performed well overall. These rankings may inform ARB selection but should be interpreted cautiously because of inconsistency, heterogeneity and sparse direct evidence.
Xuanyao Li, Xinyi Wang, Xiaolei Ren, Yalin Wang, Hua Shao, Xueli Zhang   +5 more
wiley   +1 more source

Ultrasonography Profiles in Patients with Asymptomatic Hyperuricemia [PDF]

SUMMARYBackgrounds: Asymptomatic hyperuricemia (AHU) patients mostly do not develop gouty arthritis. The best procedure to investigate whether they have MSU deposition has not been established.
Tigor Yeheskiel, -, Arinditia Triasti Putri, -, Rosy Setiawati, Rosy, Awalia, -, Paulus Rahardjo, Paulus   +4 more
core   +1 more source

Leg Ulcers in Thalassaemia: A Comparative Retrospective Review of Transfusion‐Dependent and Non‐Transfusion‐Dependent Patients

International Wound Journal, Volume 23, Issue 9, September 2026.
ABSTRACT To compare clinical and laboratory characteristics of transfusion‐dependent and non‐transfusion‐dependent beta thalassaemia patients with leg ulcers, and to identify contributing and protective factors We retrospectively reviewed 12 patients with beta thalassaemia and leg ulcers (seven transfusion‐dependent and five non‐transfusion‐dependent ...
Sacha El Khoury, Nicole Charbel, Farouk Kabbara, Joseph Klim, Ghida Ismail, Farah Ismail, Suzanne Koussa, Ali Taher   +7 more
wiley   +1 more source

Advances in pharmacotherapies for hyperuricemia

, 2023
Introduction: Hyperuricemia is an overlooked cardiovascular and renal risk factor. Epidemiological and genetic studies have shown an independent role of uric acid in the risk of coronary artery disease, heart failure, chronic kidney disease, and ...
Borghi C., Agnoletti D., Piani F.
core   +1 more source

Current role of musculoskeletal ultrasound in the detection of uratic deposits in asymptomatic hyperuricemia. [PDF]

Batna Journal of Medical Sciences
The increasing prevalence of hyperuricemia, influenced by dietary changes, underscores the importance of population-based epidemiological research, particularly in regions lacking data.
Bilal BENGANA, Salima LEFKIR–TAFIANI
doaj   +1 more source

Safety and Efficacy of Aumolertinib as First‐Line Treatment in EGFR‐Mutant Lung Adenosquamous Carcinoma: A Multicenter, Single‐Arm, Prospective Phase II Study (ARISE Study)

MedComm, Volume 7, Issue 8, August 2026.
Aumolertinib treatment resulted in improved clinical activity in EGFR‐mutant ASC. ABSTRACT Lung adenosquamous carcinoma (ASC) is a rare histological subtype of non‐small cell lung cancer (NSCLC), and prospective data regarding the efficacy of epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) in this patient population remain ...
Longfeng Zhang, Long Huang, Dingzhi Huang, Zhe Liu, Yongfeng Yu, Kang Miao, Qian Miao, Xiaobin Zheng, Yiquan Xu, Qian Chu, Gen Lin   +10 more
wiley   +1 more source

Hirudin Attenuates Uric Acid‐Induced Renal Tubular Injury via TNFRSF6B‐Mediated Suppression of NF‐κB Signaling

Pharmacology Research &Perspectives, Volume 14, Issue 4, August 2026.
ABSTRACT Hyperuricemia, characterized by elevated serum uric acid (SUA) levels, is increasingly recognized as a pathological contributor to renal injury through oxidative stress, inflammation, and apoptosis. Hirudin, a thrombin inhibitor derived from leech saliva, has recently been noted for its anti‐inflammatory properties, yet its role in ...
Yingxue Zhao, Yongjie Qin, Lanzhi He, Haikun Luo, Ying Mo, Weihai Zhou, Huamei He, Ganping Zhou, Xihua Liu   +8 more
wiley   +1 more source

Uric Acid and Chronic Kidney Disease

Kidney Medicine
The prevalence of hyperuricemia is high among people with chronic kidney disease (CKD), increasing significantly as kidney disease progresses. Whether this is an association or a cause-and-effect relationship remains controversial.
Srinath Yadlapalli, Divya K. Nekkalapudi, Jay B. Wish   +2 more
doaj   +1 more source

Potent and Sustained Lowering of Serum Uric Acid by YJH‐012‐D, a GalNAc‐Conjugated siRNA Targeting Xanthine Dehydrogenase

Pharmacology Research &Perspectives, Volume 14, Issue 4, August 2026.
We developed a GalNAc‐conjugated siRNA targeting hepatic XDH, which effectively reduces uric acid production by silencing XDH expression, offering a promising therapeutic approach for hyperuricemia. ABSTRACT Hyperuricemia (HUA) is primarily driven by hepatic overproduction of urate, mediated by xanthine dehydrogenase (XDH).
Tingke Tang, Qiuying Li, Chenguang Zhang, Yongxing Wang, Lu Yang, Haibin Huang, Yujun He, Zhi Zheng, Dong Liang, Meng Wang, Yingyu Wu, Chengjiang Zhao, Wenhao Cui   +12 more
wiley   +1 more source