Results 31 to 40 of about 186,580 (246)
scJoint integrates atlas-scale single-cell RNA-seq and ATAC-seq data with transfer learning
Nature Biotechnology, 2022 Single-cell multiomics data continues to grow at an unprecedented pace. Although several methods have demonstrated promising results in integrating several data modalities from the same tissue, the complexity and scale of data compositions present in ...
Yingxin Lin +5 more
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Scientific Reports, 2022 Assay for transposase-accessible chromatin by sequencing (ATAC-seq) is rapidly becoming the assay of choice to investigate chromatin-mediated gene regulation, largely because of low input requirements, a fast workflow, and the ability to interrogate the ...
Collin B. Merrill +4 more
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A map of bat virus receptors derived from single-cell multiomics
Scientific Data, 2022 Measurement(s) RNA-seq gene expression profiling assay • ATAC-Seq Technology Type(s) RNA-seq of coding RNA from single cells • Single cell ATAC-seq (cell index) Sample Characteristic - Organism Rhinolophus ...
Tianhang Lv +18 more
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STAR Protocols, 2023 Summary: Transposase-accessible chromatin by sequencing (ATAC-seq) has emerged as an advantageous technique to assess chromatin accessibility owing to the robustness of ''tagmentation'' process and a relatively faster library preparation. A comprehensive
Jasmine Kaur Dhall +3 more
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STAR Protocols, 2021 Summary: ATAC-seq is a versatile, adaptable, and widely adopted technique for mapping open chromatin regions. However, some biological systems, such as primary neurons, present unique challenges to its application. Conventional ATAC-seq would require the
Maya Maor-Nof +4 more
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SeATAC: a tool for exploring the chromatin landscape and the role of pioneer factors
Genome Biology, 2023 Assay for Transposase-Accessible Chromatin with sequencing (ATAC-seq) reveals chromatin accessibility across the genome. Currently, no method specifically detects differential chromatin accessibility.
Wuming Gong +2 more
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An improved ATAC-seq protocol reduces background and enables interrogation of frozen tissues
Nature Methods, 2017 We present Omni-ATAC, an improved ATAC-seq protocol for chromatin accessibility profiling that works across multiple applications with substantial improvement of signal-to-background ratio and information content.
M. Corces +21 more
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Single-cell ATAC-seq: strength in numbers [PDF]
Genome Biology, 2015 Single-cell ATAC-seq detects open chromatin in individual cells. Currently data are sparse, but combining information from many single cells can identify determinants of cell-to-cell chromatin variation.
Pott, Sebastian, Lieb, Jason D.
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ATAC-seq on Sorted Adult Mouse Neurons [PDF]
BIO-PROTOCOL, 2019 Transcription regulation is a key aspect of cellular identity established during development and maintained into adulthood. Molecular and biochemical assays that probe the genome are critical tools in exploring mechanisms of transcription regulation and cell type identity.
Erin Clark, Yasuyuki Shima, Sacha Nelson
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Cancer Medicine, 2023 Background Progestins are used as fertility‐sparing regimens for young patients with stage 1A endometrioid endometrial cancer (EEC) and atypical endometrial hyperplasia (AEH).
Lulu Wang +6 more
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