Results 171 to 180 of about 29,072 (277)

Human HRD1 Promoter Carries a Functional Unfolded Protein Response Element to Which XBP1 but not ATF6 Directly Binds [PDF]

, 2008
Keisuke Yamamoto, Nobumi Suzuki, Takahito Wada, Tetsuya Okada, Hiderou Yoshida, Randal J. Kaufman, Kiyoshi Mori   +6 more
openalex   +1 more source

BiP, GRP94, calreticulin and calnexin contribute to development of the notochord in medaka fish

Cell Structure and Function
The accumulation of unfolded or misfolded proteins in the endoplasmic reticulum (ER) activates the unfolded protein response (UPR) to maintain the homeostasis of the ER. The UPR consists of the IRE1, PERK and ATF6 pathways in vertebrates. Knockout of the
Serina Kita, Tokiro Ishikawa, Kazutoshi Mori   +2 more
doaj   +1 more source

A pilot study on gene expression of endoplasmic reticulum unfolded protein response in chronic kidney disease

Biochemistry and Biophysics Reports, 2020
Background: Chronic kidney disease (CKD) is a worldwide public health problem due to its increasing prevalence worldwide. Endoplasmic reticulum (ER) stress has been shown to play a role in the pathogenesis of various renal diseases in humans. It leads to
Rasha G. Mostafa, Abd El-Aleem Hassan Abd El-Aleem, Eman Abdella Mahmoud Fouda, Fardous Rabea Ahmed Taha, Khaled Mohamed Amin Elzorkany   +4 more
doaj  

ATF6 Activated by Proteolysis Binds in the Presence of NF-Y (CBF) Directly to thecis-Acting Element Responsible for the Mammalian Unfolded Protein Response

, 2000
Hiderou Yoshida, Tetsuya Okada, Kyosuke Haze, Hideki Yanagi, Takashi Yura, Masahiko Negishi, Kazutoshi Mori   +6 more
openalex   +1 more source

Activation of the Akt-NF-κB Pathway by Subtilase Cytotoxin through the ATF6 Branch of the Unfolded Protein Response [PDF]

, 2009
Hiroyuki Yamazaki, Nobuhiko Hiramatsu, Kunihiro Hayakawa, Yasuhiro Tagawa, Maro Okamura, Ryouji Ogata, Tao Huang, Shotaro Nakajima, Jian Yao, Adrienne W. Paton, James C. Paton, Masanori Kitamura   +11 more
openalex   +1 more source

ATF6 as a Transcription Activator of the Endoplasmic Reticulum Stress Element: Thapsigargin Stress-Induced Changes and Synergistic Interactions with NF-Y and YY1

, 2000
Ming‐Qing Li, Peter Baumeister, Binayak Roy, Trevor Phan, Dolly M. Foti, Shengzhan Luo, Amy S. Lee   +6 more
openalex   +1 more source

α-Synuclein-mediated inhibition of ATF6 processing into COPII vesicles disrupts UPR signaling in Parkinson's disease

Neurobiology of Disease, 2015
The unfolded protein response (UPR) monitors the folding environment within the endoplasmic reticulum (ER). Accumulation of misfolded proteins within the ER activates the UPR resulting in the execution of adaptive or non-adaptive signaling pathways.
Joel J. Credle, Patrick A. Forcelli, Michael Delannoy, Adam W. Oaks, Eva Permaul, Deborah L. Berry, Valeriy Duka, Jonathan Wills, Anita Sidhu   +8 more
doaj  

Pancreatic adaptive responses in alcohol abuse: Role of the unfolded protein response. [PDF]

, 2015
The majority of those who drink excessive amounts of alcohol do not develop pancreatic disease. One overarching hypothesis is that alcohol abuse requires additional risk factors, either environmental or genetic, for disease to occur.
Lugea, Aurelia, Pandol, Stephen J, Waldron, Richard T   +2 more
core   +1 more source

IRE1-mediated unconventional mRNA splicing and S2P-mediated ATF6 cleavage merge to regulate XBP1 in signaling the unfolded protein response

, 2002
Kyung‐Ho Lee, Witoon Tirasophon, Xiaohua Shen, Marek Michalak, Ron Prywes, Tetsuya Okada, Hiderou Yoshida, Kazutoshi Mori, Randal J. Kaufman   +8 more
openalex   +1 more source

The Epstein-Barr Virus Lytic Protein BMLF1 Induces Upregulation of GRP78 Expression through ATF6 Activation [PDF]

, 2021
Lee-Wen Chen, Shie-Shan Wang, Chien‐Hui Hung, Ya-Hui Hung, Chun‐Liang Lin, Pey‐Jium Chang   +5 more
openalex   +1 more source