Results 111 to 120 of about 25,612 (182)

ATG7-driven mitophagy in BMSC@CS hydrogel reprograms metabolism to boost bone regeneration

Materials Today Bio
Bone regeneration remains a formidable challenging due to impaired energy metabolism and the limited osteogenic potential of transplanted stem cells. Mitochondrial homeostasis orchestrates osteogenesis, with mitophagy maintaining the metabolic rhythm ...
Qiumei Lan, Mengtian Fan, Fengmei Zhang, Qian Gong, Jiayan Zhong, Miao Yi, Qiqi Zeng, Jianqiang Chen, Yiming Pan, Nana Geng, Biao Kuang, Yu Du, Chuanrong Zhao, Deping Zeng, Chunliang Zhao, Zhen Li, Guixue Wang, Fengjin Guo   +17 more
doaj   +1 more source

SIRT1 in Neurodegenerative Diseases: Molecular Mechanisms, Disease Relevance, and Therapeutic Potential

The FASEB Journal, Volume 40, Issue 17, 15 September 2026.
SIRT1, an NAD+‐dependent deacetylase, supports cognitive resilience by coordinating neuroprotection, synaptic plasticity, autophagy–lysosomal proteostasis, and mitochondrial energy homeostasis. Reduced or dysregulated SIRT1 is associated with protein aggregation, neuroinflammation, mitochondrial dysfunction, synaptic loss, and cognitive decline in ...
Jiabin Duan, Jiaqi Liu, Qingsheng Meng, Jiahao Liu, Sitian Yang, Fang Zhou, Jing Cao   +6 more
wiley   +1 more source

Reduction of microRNA-221 in BVDV infection enhances viral replication by targeting the ATG7-mediated autophagy pathway

Irish Veterinary Journal
Background Bovine viral diarrhoea (BVD), a condition triggered by bovine viral diarrhoea virus (BVDV), is recognized globally as a prevalent pathogen among ruminants and markedly affects the economics of animal husbandry.
Zihan Chen, Jingyu Wang, Baochun Lu, Wenxin Meng, Yufan Zhu, Qifeng Jiang, Duo Gao, Zihang Ma, Huijuan Zeng, Jinping Chen, Shizhe Liu, Zhen Wang, Kun Jia   +12 more
doaj   +1 more source

ATG7 siRNA transfection leads to down regulation of ATG7 protein.

, 2013
MG63 osteosarcoma cells were treated with vehicle (Veh), 10 µM 2-ME, 2-ME plus 100 nM ATG7siRNA (ATG7Si) and 2-ME plus 100 nM Non specific siRNA (NSsi) for 48 hrs and analyzed by western blot hybridization using anti-ATG7 and anti-actin antibodies.
Dalibel Bravo (391822), Michael J. Yaszemski (256385), Kristen L. Shogren (391820), Avudaiappan Maran (391823), Caihong Yang (391819), Ribu Goyal (391821)   +5 more
core   +1 more source

miR-223-3p靶向自噬相关蛋白7调控鼻咽癌细胞自噬

Zhongguo shiyan zhenduanxue, 2022
目的 探讨miR-223-3p是否靶向自噬相关蛋白7(Autophagy-related 7,ATG7)以调节鼻咽癌细胞的自噬。方法 使用TargetScan分析miR-223-3p与ATG7的相关性。荧光素酶测定法用于检测miR-223-3p是否靶向ATG7。通过Western blot检测miR-223-3p在鼻咽癌细胞CNE2中的过度表达或敲低,检测鼻咽癌细胞CNE2中ATG7的表达以及自噬标记蛋白P62和LC3-Ⅱ的表达。结果 miR-223-3p靶向ATG7的3’UTR位于2791 ...
doaj  

Áhrif ATG7 á efnaskipti í ávaxtaflugu

Autophagy is a core cellular recycling pathway mediated by autophagy-related (ATGs) genes. A key autophagy gene is Atg7, and its importance is reflected in a neonatal lethality observed upon total Atg7 knockout in mice.
Katrín Anna Lárusdóttir 2002-
core  

Insights on E1-like enzyme ATG7: functional regulation and relationships with aging-related diseases

Communications Biology
Autophagy is a dynamic self-renovation biological process that maintains cell homeostasis and is responsible for the quality control of proteins, organelles, and energy metabolism.
Jingwei Liu, Yutong Xiao, Liangzi Cao, Songming Lu, Siyi Zhang, Ruohan Yang, Yubang Wang, Naijin Zhang, Yang Yu, Xiwen Wang, Wendong Guo, Zhuo Wang, Hongde Xu, Chengzhong Xing, Xiaoyu Song, Liu Cao   +15 more
doaj   +1 more source

Áhrif Atg7 á æxlisvöxt í Drosophila melanogaster

Autophagy is a highly conserved catabolic process that is present in all eukaryotes and is an important factor in the formation of various cancers. In this process, ATGs play a vital role.
Kári Hertervig Ísleifsson 1996-
core   +1 more source

CircRNA0857 acts as an miRNA sponge to promote Newcastle disease virus replication via modulating autophagy. [PDF]

J Virol
Wang S, Qu Y, Liu W, Qiu X, Tan L, Song C, Liao Y, Chen L, Ding C, Ren T.   +9 more
europepmc   +1 more source

Dissecting the biochemical properties of Human ATG7 isoforms

Sjálfsát er niðurbrotsferli í frumum sem gegnir því hlutverki að halda samvægi með því að endurvinna og hreinsa upp efnivið innan frumunnar og koma þannig í veg fyrir frumudauða. Eitt af lykilpróteinum ferilsins er E-1 líka (e.
Birgitta Ósk Örvarsdóttir 1998-
core   +1 more source