Results 101 to 110 of about 25,612 (182)

Bioinformatics Identification of lncRNA‐Associated Molecular Signatures Potentially Related to Quercetin Response in Breast Cancer

Computational and Systems Oncology, Volume 6, Issue 1, December 2026.
ABSTRACT Breast cancer affects approximately one in every eight women globally, as reported by the World Health Organization. Among all female malignant tumors, breast cancer has the highest fatality rate, surpassed only by lung cancer. Advanced stages of this disease are almost always fatal, and despite the advancements in surgical techniques and ...
Mahboobeh Mehrabani Natanzi, Zohreh Khodaii, Naghmeh Zhalehjoo   +2 more
wiley   +1 more source

Design Principles of Plant Thermotolerance: Integrating Photosynthesis, Reproduction, and Field Resilience in a Warming Climate

Plant, Cell &Environment, Volume 49, Issue 11, Page 8735-8750, November 2026.
ABSTRACT Global food security is increasingly threatened by climate change, as rising temperatures compromise the yields of major staple crops, including wheat, rice, and maize. Enhancing plant thermotolerance has therefore become a critical priority for sustaining agricultural productivity.
Yuchen Qu, Wataru Yamori
wiley   +1 more source

Table1_Role of ATG7-dependent non-autophagic pathway in angiogenesis.XLSX

ATG7, one of the core proteins of autophagy, plays an important role in various biological processes, including the regulation of autophagy. While clear that autophagy drives angiogenesis, the role of ATG7 in angiogenesis remains less defined.
Yu Liang (75992), Mao Luo (165266), Jinxiang Chen (646451), Shaorun Hu (17765322), Jun Jiang (149215), Min Zeng (247802)   +5 more
core   +1 more source

The Sleeping Giant: Metabolism and Autophagy in the Generation and Survival of Dormant Polyploid Giant Cancer Cells

MedComm, Volume 7, Issue 10, October 2026.
Polyploid giant cancer cells (PGCCs) arise in response to stress and play a critical role in therapy resistance and tumor dormancy. These cells can evade conventional treatments and later contribute to cancer relapse by generating progeny through nonmitotic, amitotic mechanisms.
Silvia Guil‐Luna, María Teresa Sánchez‐Montero, Alejandra Díaz‐Chacón, Antonio Rodríguez‐Ariza   +3 more
wiley   +1 more source

Table2_Role of ATG7-dependent non-autophagic pathway in angiogenesis.XLSX

ATG7, one of the core proteins of autophagy, plays an important role in various biological processes, including the regulation of autophagy. While clear that autophagy drives angiogenesis, the role of ATG7 in angiogenesis remains less defined.
Yu Liang (75992), Mao Luo (165266), Jinxiang Chen (646451), Shaorun Hu (17765322), Jun Jiang (149215), Min Zeng (247802)   +5 more
core   +1 more source

Cancer Cell Metastasis: From Molecular Mechanisms to Therapeutic Strategies

MedComm, Volume 7, Issue 10, October 2026.
The schematic representation of intrinsic and extrinsic influences of cancer cell metastasis. Genomic evolution of metastatic tumor cells (MTCs) promotes their metastatic phenotypes and reconstruct the primary tumor microenvironment. During MTCs migration along different routes (blood circulation, lymphatic vessels, and perineuronal spaces), the ...
Yupeng Zhao, Wenchao Xu, Yibo Wang, Haoran Huang, Yu Su, Li Zhou, Jianzhou Liu, Junchao Guo   +7 more
wiley   +1 more source

Mitochondrial Fusion and Fission in Age‐Related Cardio‐Cerebral Diseases: Mechanisms and Interventions

Aging Cell, Volume 25, Issue 10, October 2026.
Mitochondrial fission‐fusion imbalance contributes to age‐related cardio‐cerebral diseases like Alzheimer's disease, Parkinson's disease, Cerebral Infarction, Arteriosclerosis, Myocardial Infarction, Cardiac valve disease, Hypertension, and Cardiomyopathy. This review summarizes its regulatory mechanisms and interventions.
Yuyao Yin, Zijian Li
wiley   +1 more source

Autophagy Flux Is Remodeled Sex‐ and Cell Type‐Specifically During Human Aging, and Is Linked to Reduced Physical Function in Older Adults

Aging Cell, Volume 25, Issue 10, October 2026.
Autophagy‐gene transcription increases with age and is uncoupled from autophagy flux. Autophagy flux is remodeled sex‐ and cell type‐specifically and is associated with worse physical function in older adults. In a pilot intervention study, elevated PBMC autophagy flux decreased following mild exercise in older adults.
Tatiana M. Moreno, Stephanie R. Heimler, Ryan J. Moran, Hava Shoshana Barkai, Lina Scandalis, Larissa Traxler, Ashley Neil, Stephen Dozier, Jaclyn Bergstrom, Alexandre R. Colas, Sanjeev S. Ranade, Anne G. Bang, Jerome Mertens, David Wing, Anthony J. Molina, Caroline Kumsta   +15 more
wiley   +1 more source

Synaptic Proteostasis in Health and Disease

Journal of Neurochemistry, Volume 170, Issue 10, October 2026.
The localised creation and degradation of proteins at the pre and postsynaptic terminal are processes that are crucial for neuronal homeostasis. Synaptic proteostasis pathways are frequently reported as dysregulated in neurodevelopmental and neurodegenerative disorders.
Paul G. Donlin‐Asp, Emma L. Clayton
wiley   +1 more source

‘Candidatus Liberibacter asiaticus’ secretory protein SDE5640 activates host autophagy dependent on PSMD10 to mediate PBA1 degradation

The Plant Journal, Volume 128, Issue 1, October 2026.
Significance Statement In healthy citrus cells, CsPSMD10 directly binds CsATG8 and targets it for ubiquitin‐dependent degradation by the intact 26S proteasome, maintaining low free CsATG8 levels and suppressing autophagy to preserve immune homeostasis.
Yalin Mei, Xinyi Deng, Zaiyu Yang, Shimin Fu, Changyong Zhou, Xuefeng Wang   +5 more
wiley   +1 more source