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Atg7 in AML: a double-edged sword?
Blood, 2016In this issue of Blood, Piya et al have identified the autophagy-related E1 ligase Atg7, a critical autophagy component associated with unfavorable outcomes in acute myeloid leukemia (AML), as a potential target in this disease.1 If validated, this study could provide a foundation for disrupting Atg7 in AML therapy.
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MIR137 Regulates Starvation-Induced Autophagy by Targeting ATG7
Journal of Molecular Neuroscience, 2015Autophagy is a cellular catabolic mechanism in response to stress conditions and has been implicated in the progression and chemoresistance of various cancers. Human microR-137 (MIR137) is involved in neuronal maturation and neurogenesis, while little is known about its role in cancer. In this study, we showed that starvation increased the formation of
Yuecheng, Zeng +4 more
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m6A mRNA methylation controls autophagy and adipogenesis by targeting Atg5 and Atg7
Autophagy, 2020Xinxia Wang, Ruifan Wu, Yuanling Zhao
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ATG7 Promotes Bladder Cancer Invasion via Autophagy‐Mediated Increased ARHGDIB mRNA Stability
Advanced Science, 2019Junlan Zhu +2 more
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Atg7 Regulates Brain Angiogenesis via NF-κB-Dependent IL-6 Production
International Journal of Molecular Sciences, 2017Ke Zhang, Liu Cao, Wei-Dong Zhao
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Neuroprotection by selective neuronal deletion of Atg7 in neonatal brain injury
Autophagy, 2016Cuicui Xie +2 more
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