Results 11 to 20 of about 793,722 (339)

Atherosclerosis [PDF]

open access: yesNature Reviews Disease Primers, 2019
Atherosclerosis, the formation of fibrofatty lesions in the artery wall, causes much morbidity and mortality worldwide, including most myocardial infarctions and many strokes, as well as disabling peripheral artery disease. Development of atherosclerotic lesions probably requires low-density lipoprotein, a particle that carries cholesterol through the ...
Peter, Libby   +7 more
openaire   +4 more sources

Atherosclerosis [PDF]

open access: yesAnnals of the Rheumatic Diseases, 2002
Is atherosclerosis a cellular or humoral mediated autoimmune disease?
Y, Sherer, Y, Shoenfeld
openaire   +2 more sources

“Jnking” atherosclerosis [PDF]

open access: yesCellular and Molecular Life Sciences, 2005
ISSN:1420 ...
Sumara, G., Belwal, M., Ricci, R.
openaire   +3 more sources

Atherosclerosis [PDF]

open access: yesNature, 2000
Atherosclerosis, a disease of the large arteries, is the primary cause of heart disease and stroke. In westernized societies, it is the underlying cause of about 50% of all deaths. Epidemiological studies have revealed several important environmental and genetic risk factors associated with atherosclerosis.
openaire   +2 more sources

Porphyromonas gingivalis lipopolysaccharide alters atherosclerotic-related gene expression in oxidized low-density-lipoprotein-induced macrophages and foam cells [PDF]

open access: yes, 2011
The molecular mechanism between atherosclerosis formation and periodontal pathogens is not clear although positive correlation between periodontal infections and cardiovascular diseases has been reported.
de Winther   +23 more
core   +2 more sources

D4F alleviates macrophage-derived foam cell apoptosis by inhibiting the NF-κB-dependent Fas/FasL pathway

open access: yesScientific Reports, 2017
This study was designed to explore the protective effect of D4F, an apolipoprotein A-I mimetic peptide, on nuclear factor-κB (NF-κB)-dependent Fas/Fas ligand (FasL) pathway-mediated apoptosis in macrophages induced by oxidized low-density lipoprotein (ox-
Hua Tian   +9 more
doaj   +1 more source

In vivo effects of anacetrapib on preβ HDL: improvement in HDL remodeling without effects on cholesterol absorption

open access: yesJournal of Lipid Research, 2013
Cholesteryl ester transfer protein (CETP) transfers cholesteryl ester and triglyceride between HDL and apoB-containing lipoproteins. Anacetrapib (ANA), a reversible inhibitor of CETP, raises HDL cholesterol and lowers LDL cholesterol in dyslipidemic ...
Sheng-Ping Wang   +8 more
doaj   +1 more source

Macrophage autophagy in atherosclerosis [PDF]

open access: yes, 2013
Macrophages play crucial roles in atherosclerotic immune responses. Recent investigation into macrophage autophagy (AP) in atherosclerosis has demonstrated a novel pathway through which these cells contribute to vascular inflammation.
Carnuccio, R.   +5 more
core   +2 more sources

Niacin Inhibits Vascular Inflammation via Downregulating Nuclear Transcription Factor-κB Signaling Pathway

open access: yesMediators of Inflammation, 2014
The study aimed to investigate the effect of niacin on vascular inflammatory lesions in vivo and in vitro as well as its lipid-regulating mechanism. In vivo study revealed that niacin downregulated the levels of inflammatory factors (IL-6 and TNF-α) in ...
Yanhong Si   +10 more
doaj   +1 more source

Molecular characterization of two monoclonal antibodies specific for the LDL receptor-binding site of human apolipoprotein E.

open access: yesJournal of Lipid Research, 1995
Apolipoprotein E (apoE), a 299 amino acid protein, is a ligand for the low density lipoprotein receptor (LDLr). It has been established that basic amino acids situated between apoE residues 136 and 150 participate in the interaction of apoE with the LDLr.
R Raffai   +9 more
doaj   +1 more source

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