Results 21 to 30 of about 473,671 (315)

Atherosclerosis [PDF]

open access: yesNature, 2000
Atherosclerosis, a disease of the large arteries, is the primary cause of heart disease and stroke. In westernized societies, it is the underlying cause of about 50% of all deaths. Epidemiological studies have revealed several important environmental and genetic risk factors associated with atherosclerosis.
openaire   +2 more sources

Lipoproteins and Atherosclerosis [PDF]

open access: yesJournal of Gerontology, 1951
Author(s): Gofman, John W.; Lindgren, Frank T.; Jones, Hardin B.; Lyon, Thomas P.; Strisower, Beverly.
Gofman, John W.   +4 more
openaire   +3 more sources

Adipose tissue cholesteryl ester transfer protein mRNA in response to probucol treatment: cholesterol and species dependence

open access: yesJournal of Lipid Research, 1993
Probucol treatment results in an increase in plasma concentrations of cholesteryl ester transfer protein (CETP) which may account, in part, for the effects of this agent on plasma concentrations of HDL cholesterol. We have examined the mechanism by which
EM Quinet   +5 more
doaj   +1 more source

Quantifying apoprotein synthesis in rodents: coupling LC-MS/MS analyses with the administration of labeled water

open access: yesJournal of Lipid Research, 2012
Stable isotope tracer studies of apoprotein flux in rodent models present difficulties as they require working with small volumes of plasma. We demonstrate the ability to measure apoprotein flux by administering either 2H- or 18O-labeled water to mice ...
Haihong Zhou   +14 more
doaj   +1 more source

The Role of Costimulatory Receptors of the Tumour Necrosis Factor Receptor Family in Atherosclerosis [PDF]

open access: yes, 2012
Atherosclerosis is a chronic inflammatory disease that is mediated by both the innate and adaptive immune responses. T lymphocytes, that together with B cells are the cellular effectors of the adaptive immune system, are currently endowed with crucial ...
Ricardo F. Antunes   +8 more
core   +1 more source

Cholesteryl ester transfer protein (CETP) mRNA abundance in human adipose tissue: relationship to cell size and membrane cholesterol content.

open access: yesJournal of Lipid Research, 1995
Cholesteryl ester transfer protein (CETP) has a well-defined role in plasma neutral lipid transport. CETP synthesized by human adipose tissue may contribute to the plasma CETP pool. CETP mRNA abundance increases in subcutaneous adipose tissue in response
T Radeau   +5 more
doaj   +1 more source

Association of Epicardial Adipose Tissue with Coronary Atherosclerosis Is Region-Specific and Independent of Conventional Risk Factors and Intra- Abdominal Adiposity

open access: yes, 2011
Objective: To elucidate which measurement of epicardial adipose tissue ( EAT) best reflects its atherogenic risk, we examined the associations between different EAT measurements and various atherosclerotic parameters of the entire coronary tree and ...
王宗道;李文正;石富元;黃建華;陳文鍾;李源德;施庭芳;陳明豐   +1 more
core   +1 more source

Isolation and characterization of an apoA-II-containing lipoprotein (LP-A-II:B complex) from plasma very low density lipoproteins of patients with Tangier disease and type V hyperlipoproteinemia.

open access: yesJournal of Lipid Research, 1991
Previous studies have shown that very low density lipoproteins (VLDL) from patients with Tangier disease are less effective as a substrate for human milk lipoprotein lipase (LPL) than VLDL from normal controls as assessed by measuring the first order ...
P Alaupovic   +6 more
doaj   +1 more source

ATHEROSCLEROSIS

open access: yesInternational Journal of Clinical Practice, 1993
George Payling Wright was Professor of Pathology at Guy's Hospital when I went there as a student in 1941 and I came to know him in 1943. He was a great man, a great scholar and an inspired teacher. Of unimpressive appearance, it was only when he began to lecture or to explain or to demonstrate that his great abilities became apparent.
openaire   +2 more sources

D4F alleviates macrophage-derived foam cell apoptosis by inhibiting CD36 expression and ER stress-CHOP pathway[S]

open access: yesJournal of Lipid Research, 2015
This study was designed to explore the protective effect of D4F, an apoA-I mimetic peptide, on oxidized LDL (ox-LDL)-induced endoplasmic reticulum (ER) stress-CCAAT/enhancer-binding protein (C/EBP) homologous protein (CHOP) pathway-mediated apoptosis in ...
Shutong Yao   +11 more
doaj   +1 more source

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