Results 31 to 40 of about 514,218 (262)

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Association between human T cell leukemia virus type-1 (HTLV-1) infection and advanced periodontitis in relation to atherosclerosis among elderly Japanese: a cross-sectional study [PDF]

, 2019
Background: Human T cell leukemia virus type-1 (HTLV-1) stimulates inflammation activity. Our previous study revealed a positive association between asymptomatic HTLV-1 infection and advanced periodontitis among elderly Japanese individuals with low ...
Kawashiri, Shin-Ya, Kawakami, Atsushi, Kitamura, Masayasu, Kawasaki, Koji, Saito, Toshiyuki, Shimizu, Yuji, Maeda, Takahiro, Fukuda, Hideki, Iwasaki, Takahiro, Kiyoura, Kairi, Yamanashi, Hirotomo, Hayashida, Hideaki, Furugen, Reiko   +12 more
core   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Recent advances in the treatment of venous thromboembolism in the era of the direct oral anticoagulants [version 1; referees: 2 approved]

F1000Research, 2017
The direct oral anticoagulants (DOACs) have now supplanted vitamin K antagonists (VKAs) for the treatment of venous thromboembolism (VTE). The DOACs include dabigatran, which inhibits thrombin, and rivaroxaban, apixaban, and edoxaban, which inhibit ...
Jeffrey I. Weitz, Iqbal H. Jaffer, James C. Fredenburgh   +2 more
doaj   +1 more source

Influence of dietary intervention on microvascular endothelial function in coronary patients and atherothrombotic risk of recurrence

Scientific Reports, 2021
Endothelial dysfunction is a key player in both the onset and development of atherosclerosis. No study has examined whether healthy dietary patterns can improve microvascular endothelial function in patients with coronary heart disease (CHD) in the long ...
Marta Millan-Orge, Jose D. Torres-Peña, Antonio Arenas-Larriva, Gracia M. Quintana-Navarro, Patricia Peña-Orihuela, Juan F. Alcala-Diaz, Raul M. Luque, Fernando Rodriguez-Cantalejo, Niki Katsiki, Jose Lopez-Miranda, Pablo Perez-Martinez, Javier Delgado-Lista   +11 more
doaj   +1 more source

Owning a Pet Is Associated with Changes in the Composition of Gut Microbiota and Could Influence the Risk of Metabolic Disorders in Humans

Animals, 2021
Pet ownership positively influences clinical outcomes in cardiovascular prevention. Additionally, cardiovascular disease (CVD) has been previously linked to microbiota dysbiosis.
Javier Arenas-Montes, Pablo Perez-Martinez, Cristina Vals-Delgado, Juan Luis Romero-Cabrera, Magdalena P. Cardelo, Ana Leon-Acuña, Gracia M. Quintana-Navarro, Juan F. Alcala-Diaz, Jose Lopez-Miranda, Antonio Camargo, Francisco Perez-Jimenez   +10 more
doaj   +1 more source

Evaluation of possible subclinical atherosclerosis in adolescents with a family history of premature atherosclerosis

, 2012
Conclusion: Among several markers of subclinical atherosclerosis, the CSI was significantly higher in adolescents who had a family history of premature atherosclerosis.
Erkorkmaz, Ünal
core   +1 more source

Handgrip strength and subclinical carotid atherosclerosis in relation to platelet levels among hypertensive elderly Japanese [PDF]

, 2017
Age-related disruption of microvascular endothelium exacerbates hypertension and sarcopenia; and atherosclerosis is a well-known biological response to vascular endothelial injury.
Kawashiri, Shin-Ya, Jun Koyamatsu, Nagayoshi, Mako, Yuji Shimizu, Koyamatsu, Jun, Mako Nagayoshi, Inoue, Keita, Shimizu, Yuji, Maeda, Takahiro, Keita Inoue, Takahiro Maeda, Shin-Ya Kawashiri, Yamanashi, Hirotomo, Nagata, Yasuhiro, Yasuhiro Nagata, Sato, Shimpei, Hirotomo Yamanashi, Kadota, Koichiro, Shimpei Sato, Koichiro Kadota   +19 more
core   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Retracted:Pulmonary Hypertension due to a Pulmonary Artery Leiomyosarcoma: A Case Report.

ARYA Atherosclerosis, 2015
The article titled "Pulmonary Hypertension due to a Pulmonary Artery Leiomyosarcoma: A Case Report."(1), published online on March 2014 in ARYA Atherosclerosis Journal, and in Volume 10, pp.
ARYA Atherosclerosis
doaj