Results 11 to 20 of about 514,218 (262)
Intensive Care Medicine Experimental, 2018 Background Despite increasing ethical standards for conducting animal research, death is still often used as an endpoint in mouse sepsis studies. Recently, the Murine Sepsis Score (MSS), Mouse Clinical Assessment Score for Sepsis (M-CASS), and Mouse ...
Safiah H. C. Mai +7 more
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Scientific Reports, 2017 This study was designed to explore the protective effect of D4F, an apolipoprotein A-I mimetic peptide, on nuclear factor-κB (NF-κB)-dependent Fas/Fas ligand (FasL) pathway-mediated apoptosis in macrophages induced by oxidized low-density lipoprotein (ox-
Hua Tian +9 more
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Journal of Lipid Research, 2013 Cholesteryl ester transfer protein (CETP) transfers cholesteryl ester and triglyceride between HDL and apoB-containing lipoproteins. Anacetrapib (ANA), a reversible inhibitor of CETP, raises HDL cholesterol and lowers LDL cholesterol in dyslipidemic ...
Sheng-Ping Wang +8 more
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Mediators of Inflammation, 2014 The study aimed to investigate the effect of niacin on vascular inflammatory lesions in vivo and in vitro as well as its lipid-regulating mechanism. In vivo study revealed that niacin downregulated the levels of inflammatory factors (IL-6 and TNF-α) in ...
Yanhong Si +10 more
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Journal of Lipid Research, 1995 Apolipoprotein E (apoE), a 299 amino acid protein, is a ligand for the low density lipoprotein receptor (LDLr). It has been established that basic amino acids situated between apoE residues 136 and 150 participate in the interaction of apoE with the LDLr.
R Raffai +9 more
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eNOS protects from atherosclerosis despite relevant superoxide production by the enzyme in apoE mice. [PDF]
, 2012 All three nitric oxide synthase (NOS) isoforms are expressed in atherosclerotic plaques. NOS enzymes in general catalyse NO production. However, under conditions of substrate and cofactor deficiency, the enzyme directly catalyse superoxide formation ...
Sabine Grüner +27 more
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Journal of Lipid Research, 1993 Probucol treatment results in an increase in plasma concentrations of cholesteryl ester transfer protein (CETP) which may account, in part, for the effects of this agent on plasma concentrations of HDL cholesterol. We have examined the mechanism by which
EM Quinet +5 more
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Data in Brief, 2016 The data presented in this article describe an effect of N-acetylneuraminic acid and/or quercetin on the inflammatory proteins expressions (TNF-α, ICAM-1, VCAM-1 and MOMA-2) and the N-acetylneuraminic acid (NANA) levels of apolipoprotein E-deficient mice
Rongrong Dong +13 more
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Journal of Lipid Research, 2012 Stable isotope tracer studies of apoprotein flux in rodent models present difficulties as they require working with small volumes of plasma. We demonstrate the ability to measure apoprotein flux by administering either 2H- or 18O-labeled water to mice ...
Haihong Zhou +14 more
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, 2011 Objective: To elucidate which measurement of epicardial adipose tissue ( EAT) best reflects its atherogenic risk, we examined the associations between different EAT measurements and various atherosclerotic parameters of the entire coronary tree and ...
王宗道;李文正;石富元;黃建華;陳文鍾;李源德;施庭芳;陳明豐 +1 more
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