Results 21 to 30 of about 620,434 (340)
Targeting inflammation in atherosclerosis — from experimental insights to the clinic
Nature reviews. Drug discovery, 2021 Atherosclerosis, a dominant and growing cause of death and disability worldwide, involves inflammation from its inception to the emergence of complications.
O. Soehnlein, P. Libby
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Biochimica et Biophysica Acta (BBA) - Biomembranes, 2013 Atherosclerosis, a chronic inflammatory disease of the vessel wall, involves multiple cell types of different origins, and complex interactions and signaling pathways between them. Autocrine and paracrine communication pathways provided by cytokines, chemokines, growth factors and lipid mediators are central to atherogenesis.
Pfenniger Anna +2 more
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Macrophage-targeted nanomedicine for the diagnosis and treatment of atherosclerosis
Nature Reviews Cardiology, 2021 Nanotechnology could improve our understanding of the pathophysiology of atherosclerosis and contribute to the development of novel diagnostic and therapeutic strategies to further reduce the risk of cardiovascular disease.
Wei Chen +5 more
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Alcohol and atherosclerosis [PDF]
Anais da Academia Brasileira de Ciências, 2001 Atherosclerosis is manifested as coronary artery disease (CAD), ischemic stroke and peripheral vascular disease. Moderate alcohol consumption has been associated with reduction of CAD complications. Apparently, red wine offers more benefits than any other kind of drinks, probably due to flavonoids. Alcohol alters lipoproteins and the coagulation system.
DA LUZ, PROTASIO L., COIMBRA, SILMARA R.
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When Is Atherosclerosis Not Atherosclerosis? [PDF]
Arteriosclerosis, Thrombosis, and Vascular Biology, 2000 To the Editor: When is atherosclerosis not atherosclerosis? In the last decade, there have been 2 revolutions in the study of atherosclerosis. On the one hand, a more sophisticated appreciation of the relationship between the morphology and fate of human atherosclerotic plaques and clinical outcomes has been developed.
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Circulation Research, 2016 Advances in atherosclerosis imaging technology and research have provided a range of diagnostic tools to characterize high-risk plaque in vivo; however, these important vascular imaging methods additionally promise great scientific and translational applications beyond this quest.
Tarkin, Jason M +7 more
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, 2017 In this chapter, we discuss the manner through which the immune system regulates the cardiovascular system in health and disease. We define the cardiovascular system and elements of atherosclerotic disease, the main focus in this chapter. Herein we elaborate on the disease process that can result in myocardial infarction (heart attack), ischaemic ...
Rahman, MS, Woollard, K
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Nature, 2000 Atherosclerosis, a disease of the large arteries, is the primary cause of heart disease and stroke. In westernized societies, it is the underlying cause of about 50% of all deaths. Epidemiological studies have revealed several important environmental and genetic risk factors associated with atherosclerosis.
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Phosphatidylserine in atherosclerosis [PDF]
Current Opinion in Lipidology, 2016 Purpose of review It is now widely acknowledged that phosphatidylserine is a multifunctional bioactive lipid. In this review, we focus on the function of phosphatidylserine in modulating cholesterol metabolism, influencing inflammatory response and regulating coagulation system, and discuss promising phosphatidylserine-based ...
Darabi, Maryam, Kontush, Anatol
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Inflammation, atherosclerosis, and coronary artery disease.
New England Journal of Medicine, 2005 ecent research has shown that inflammation plays a key role in coronary artery disease (CAD) and other manifestations of atherosclerosis. Immune cells dominate early atherosclerotic lesions, their effector molecules accelerate progression of the lesions,
G. Hansson
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