Results 31 to 40 of about 387,962 (319)

Hypertriglyceridemia and atherosclerosis [PDF]

open access: yesLipids in Health and Disease, 2017
Atherosclerotic cardiovascular disease (ASCVD) is the leading cause of death and it has been confirmed that increased low density lipoprotein cholesterol (LDL-C) is an independent risk factor for atherosclerosis. Recently, the increasing evidence has showed that hypertriglyceridemia is associated with incremental ASCVD risk.
Jia Peng   +4 more
openaire   +4 more sources

Circulating Markers Reflect Both Anti- and Pro-Atherogenic Drug Effects in ApoE-Deficient Mice

open access: yesBiomarker Insights, 2008
Background Current drug therapy of atherosclerosis is focused on treatment of major risk factors, e.g. hypercholesterolemia while in the future direct disease modification might provide additional benefits.
Birong Liao   +16 more
doaj   +1 more source

Automatic Diagnosis of Carotid Atherosclerosis Using a Portable Freehand 3D Ultrasound Imaging System [PDF]

open access: yesarXiv, 2023
The objective of this study is to develop a deep-learning based detection and diagnosis technique for carotid atherosclerosis using a portable freehand 3D ultrasound (US) imaging system. A total of 127 3D carotid artery scans were acquired using a portable 3D US system which consisted of a handheld US scanner and an electromagnetic tracking system. A U-
arxiv  

Medial Injury/Dysfunction Induced Granulation Tissue Repair is the Pathogenesis of Atherosclerosis [PDF]

open access: yesarXiv, 2020
Atherosclerosis, a chronic lesion of vascular wall, remains a leading cause of death and loss of life years. Classical hypotheses for atherosclerosis are long-standing mainly to explain atherogenesis. Unfortunately, these hypotheses may not explain the variation in the susceptibility to atherosclerosis.
arxiv  

Inflammation and Atherosclerosis [PDF]

open access: yesCells, 2021
This 11-chapter Special Issue of Cells spans the gamut from basic science in mechanistic animal models to translational science to outcomes of clinical trials, all focused on the role of inflammation in atherosclerosis [...]
openaire   +4 more sources

The power of microRNA regulation—insights into immunity and metabolism

open access: yesFEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto   +2 more
wiley   +1 more source

Owning a Pet Is Associated with Changes in the Composition of Gut Microbiota and Could Influence the Risk of Metabolic Disorders in Humans

open access: yesAnimals, 2021
Pet ownership positively influences clinical outcomes in cardiovascular prevention. Additionally, cardiovascular disease (CVD) has been previously linked to microbiota dysbiosis.
Javier Arenas-Montes   +10 more
doaj   +1 more source

A numerical model based on the curvilinear coordinate system for the MAC method simplified [PDF]

open access: yesSemina: Exact and Technological Science, Londrina, v. 40, n. 2, p. 42-53, ago./dez. 2018, 2019
In this paper we developed a numerical methodology to study some incompressible fluid flows without free surface, using the curvilinear coordinate system and whose edge geometry is constructed via parametrized spline. First, we discussed the representation of the Navier-Stokes and continuity equations on the curvilinear coordinate system, along with ...
arxiv   +1 more source

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan   +10 more
wiley   +1 more source

INSULIN AND ATHEROSCLEROSIS

open access: yesThe Lancet, 1969
The idea that excessive concentrations of insulin might contribute to the development of atherosclerosis appeared in the mid 1960s and the evidence was first reviewed in a paper published in 1969 [1]. Since then, data, both clinical and experimental, has continued to accumulate, most of it supportive of the hypothesis, although some of the details have
openaire   +4 more sources

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