Results 31 to 40 of about 793,722 (339)
This study was designed to explore the protective effect of D4F, an apoA-I mimetic peptide, on oxidized LDL (ox-LDL)-induced endoplasmic reticulum (ER) stress-CCAAT/enhancer-binding protein (C/EBP) homologous protein (CHOP) pathway-mediated apoptosis in ...
Shutong Yao +11 more
doaj +1 more source
Coronary age, based on coronary calcium measurement, is increased in patients with morbid obesity [PDF]
Purpose: Obesity is a well-known of risk factor for atherosclerosis. However, recently an "obesity paradox" has been discussed, which is considered as a protective effect of obesity on the development coronary artery disease (CAD).
Białecki, Marcin +3 more
core +1 more source
Atherosclerosis follows the deposition, retention, and oxidative modification of lipoproteins, especially low-density lipoprotein (LDL) in the walls of large arteries. Uptake of oxidized LDL results in the formation of macrophage foam cells. Proliferation of vascular smooth muscle cells and secretion of extracellular matrix contribute "fibrous ...
Lee, J +3 more
openaire +2 more sources
Previous studies have shown that very low density lipoproteins (VLDL) from patients with Tangier disease are less effective as a substrate for human milk lipoprotein lipase (LPL) than VLDL from normal controls as assessed by measuring the first order ...
P Alaupovic +6 more
doaj +1 more source
The metabolic syndrome adds utility to the prediction of mortality over its components: The Vietnam Experience Study [PDF]
Background\ud The metabolic syndrome increases mortality risk. However, as “non-affected” individuals may still have up to two risk factors, the utility of using three or more components to identify the syndrome, and its predictive advantage over ...
Anna C. Phillips +24 more
core +1 more source
Lipoproteins and Atherosclerosis [PDF]
Author(s): Gofman, John W.; Lindgren, Frank T.; Jones, Hardin B.; Lyon, Thomas P.; Strisower, Beverly.
Gofman, John W. +4 more
openaire +3 more sources
Circulating Markers Reflect Both Anti- and Pro-Atherogenic Drug Effects in ApoE-Deficient Mice
Background Current drug therapy of atherosclerosis is focused on treatment of major risk factors, e.g. hypercholesterolemia while in the future direct disease modification might provide additional benefits.
Birong Liao +16 more
doaj +1 more source
Roles of reconstituted high-density lipoprotein nanoparticles in cardiovascular disease: A new paradigm for drug discovery [PDF]
Epidemiological results revealed that there is an inverse correlation between high-density lipoprotein (HDL) cholesterol levels and risks of atherosclerotic cardiovascular disease (ASCVD).
Huang, Hui +3 more
core +2 more sources
Compared to BALB/c mice, inbred C57BL/6 mice are more susceptible to developing fatty streak atherosclerotic lesions when fed a cholesterol-rich diet containing taurocholate. We examined the metabolic basis for the taurocholate requirement.
S Dueland +5 more
doaj +1 more source
Hubungan Kadar Apolipoprotein B Dengan Aterosklerosis Arteri Karotis Interna Pada Pasien Pasca Stroke Iskemik [PDF]
Background: Ischemic stroke is caused by brain artery obstruction or narrowing called atherosclerosis. Its marker is the thickness of tunica intima-media (intima-media thickness / IMT) of the artery. Apolipoprotein B is the indicator of atherosclerosis
Teguh, Haryo
core

