Exploration of the atherosclerotic plaque
During the past 3 decades we have achieved a better understanding of the atherosclerotic process. It has been described as a series of changes in the intima of arteries consisting of the focal accumulation of lipids, complex carbohydrates, blood and blood products, fibrous tissues, and calcium that are also associated with changes in the media.
John H. Ip, V Fuster, JH Chesebro
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Utility of 2013 American College of Cardiology/American Heart Association Cholesterol Guidelines in HIV-Infected Adults With Carotid Atherosclerosis. [PDF]
BackgroundAlthough HIV is associated with increased atherosclerotic cardiovascular disease (CVD) risk, it is unknown whether guidelines can identify HIV-infected adults who may benefit from statins.
Deeks, Steven+8 more
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Regulation of atherosclerotic plaque inflammation [PDF]
AbstractThe immune reactions that regulate atherosclerotic plaque inflammation involve chemokines, lipid mediators and costimulatory molecules. Chemokines are a family of chemotactic cytokines that mediate immune cell recruitment and control cell homeostasis and activation of different immune cell types and subsets.
Magnus Bäck+5 more
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Ultrafast laser ablation for targeted atherosclerotic plaque removal [PDF]
Coronary artery disease, the main cause of heart disease, develops as immune cells and lipids accumulate into plaques within the coronary arterial wall.
Conkey, Donald B.+8 more
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Exercise and Coronary Atherosclerosis: Observations, Explanations, Relevance, and Clinical Management. [PDF]
Physical activity and exercise training are effective strategies for reducing the risk of cardiovascular events, but multiple studies have reported an increased prevalence of coronary atherosclerosis, usually measured as coronary artery calcification ...
Aengevaeren, VL+7 more
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Exploiting macrophage autophagy-lysosomal biogenesis as a therapy for atherosclerosis [PDF]
Macrophages specialize in removing lipids and debris present in the atherosclerotic plaque. However, plaque progression renders macrophages unable to degrade exogenous atherogenic material and endogenous cargo including dysfunctional proteins and ...
Ali, Sahl+19 more
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Subsurface ablation of atherosclerotic plaque using ultrafast laser pulses [PDF]
We perform subsurface ablation of atherosclerotic plaque using ultrafast pulses. Excised mouse aortas containing atherosclerotic plaque were ablated with ultrafast near-infrared (NIR) laser pulses.
Conkey, Donald B.+7 more
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Invasive angiography has been widely accepted as the gold standard to diagnose cardiovascular pathologies. Despite its superior resolution of demonstrating atherosclerotic plaque in terms of degree of lumen stenosis, the morphological assessment for the ...
Zhonghua Sun
doaj +1 more source
Reduced Necrosis and Content of Apoptotic M1 Macrophages in Advanced Atherosclerotic Plaques of Mice With Macrophage-Specific Loss of Trpc3 [PDF]
In previous work we reported that ApoeKO mice transplanted with bone marrow cells deficient in the Transient Receptor Potential Canonical 3 (TRPC3) channel have reduced necrosis and number of apoptotic macrophages in advanced atherosclerotic plaques ...
Birnbaumer, Lutz+3 more
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Percent atheroma volume: Optimal variable to report whole-heart atherosclerotic plaque burden with coronary CTA, the PARADIGM study. [PDF]
BACKGROUND AND AIMS:Different methodologies to report whole-heart atherosclerotic plaque on coronary computed tomography angiography (CCTA) have been utilized.
Al Hussein, Omar+37 more
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