Results 1 to 10 of about 506,852 (135)
Proceedings of the 2009 ACM symposium on Applied Computing, 2009 Got my account today at the bank at the USP Leste campus.
Mohammad Gias Uddin, Mohammad Zulkernine
+4 more sources
Atrophy, oxidative switching and ultrastructural defects in skeletal muscle of the ataxia telangiectasia mouse model [PDF]
, 2019 Ataxia telangiectasia is a rare, multi system disease caused by ATM kinase deficiency. Atm-knockout mice recapitulate premature aging, immunodeficiency, cancer predisposition, growth retardation and motor defects, but not cerebellar neurodegeneration and
Aguanno, Salvatore +8 more
core +1 more source
Personalized ATMs: Improve ATMs Usability [PDF]
, 2011 Using customization in products and services is one of the important methods for obtaining customers’ satisfaction. In this paper, the personalized ATMs have been introduced which as one of the objectives, using personalization and customization methods, improve the efficiency and simplicity of usage of the ATMs and enable the users to benefit from the
Armin Kamfiroozie, Marzieh Ahmadzadeh
openaire +1 more source
Targeting ATM pathway for therapeutic intervention in cancer [PDF]
, 2012 The Ataxia Telangiectasia Mutated gene encodes the ATM protein, a key element in the DNA damage response (DDR) signalling pathway responsible for maintaining genomic integrity within the cell.
Chakarov, Stoyan +4 more
core +3 more sources
Current Biology, 2003 What are ATM and ATR? Ataxia telangiectasia mutated (ATM) and ATM and RAD3-related (ATR) are members of the phosphatidyl-inositol 3-kinase (PI 3-kinase) like family of protein kinases (PIKKs). These large proteins – predicted molecular masses for ATM and ATR are 351kDa and 301kDa, respectively – are involved in cellular responses to DNA damage.Don't ...
Bradbury, Jane M., Jackson, Stephen P.
openaire +2 more sources
ATM deficiency results in accumulation of DNA-Topoisomerase I covalent intermediates in neural cells [PDF]
, 2013 Accumulation of peptide-linked DNA breaks contributes to neurodegeration in humans. This is typified by defects in tyrosyl DNA phosphodiesterase 1 (TDP1) and human hereditary ataxia.
Alagoz, Meryem +3 more
core +2 more sources
The tumor-promoting functions of Ataxia-telangiectasia mutated (ATM) in cancer cells [PDF]
, 2015 textAtaxia-telangiectasia mutated (ATM) protein kinase regulates the DNA damage response (DDR) and is associated with cancer suppression by protecting cells from DNA double-strand breaks (DSBs). However, how ATM functions outside of DSB signaling is less
Chen, Wei-Ta, active 21st century
core +1 more source
ATM in focus:a damage sensor and cancer target [PDF]
, 2012 The ability of a cell to conserve and maintain its native DNA sequence is fundamental for the survival and normal functioning of the whole organism and protection from cancer development.
Khalil, Hilal S. +2 more
core +4 more sources
Endogenous topoisomerase II-mediated DNA breaks drive thymic cancer predisposition linked to ATM deficiency [PDF]
, 2020 The ATM kinase is a master regulator of the DNA damage response to double-strand breaks (DSBs) and a well-established tumour suppressor whose loss is the cause of the neurodegenerative and cancer-prone syndrome Ataxia-Telangiectasia (A-T).
Bernal Lozano, Cristina +10 more
core +3 more sources
Connectionless communications using the Asynchronous Transfer Mode [PDF]
, 1995 For a large number of applications, there is a strong need for the provision of a connectionless service by the B-ISDN. However, the cell-based ATM, which is used for switching and multiplexing in this public telecommunication network, is a connection ...
Heijenk, Gerhard Jan
core +8 more sources