Results 31 to 40 of about 84,293 (267)

Black Carbon in Urban and Suburban Hangzhou: Spatiotemporal Variation, Precipitation Scavenging, and Policy Impacts

Atmosphere
Black carbon (BC) aerosols significantly impact regional air quality and global climate as important light-absorbing atmospheric particles. Using high-temporal resolution BC observation data from urban and suburban sites in Hangzhou and PM10 ...
Mengjing Zhu, Honghui Xu, Meng Shan, Huansang Chen, Yilei Dong, Yuyun Lei   +5 more
doaj   +1 more source

A Comparative Study of Cloud Microphysics Schemes in Simulating a Quasi-Linear Convective Thunderstorm Case

Remote Sensing
An investigation is undertaken to explore a sudden quasi-linear precipitation and gale event that transpired in the afternoon of 30 May 2024 over Beijing.
Juan Huo, Yongheng Bi, Hui Wang, Zhan Zhang, Qingping Song, Minzheng Duan, Congzheng Han   +6 more
doaj   +1 more source

Understanding ozone variability in spatial responses to emissions and meteorology in China using interpretable machine learning

iScience
Summary: To effectively control regional ozone pollution, it is crucial to investigate ozone variability in spatial responses to emissions and meteorology.
Xin Zhang, Wei-Chun Zhang, Wei Wu, Hong-Bin Liu   +3 more
doaj   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Retrieval of Stratospheric Ozone Profiles from Limb Scattering Measurements of the Backward Limb Spectrometer on Chinese Space Laboratory Tiangong-2: Preliminary Results

Remote Sensing, 2022
The Backward Limb Spectrometer (BLS) onboard the Tiangong-2 (TG-2) space laboratory, the first spaceborne limb sounding instrument of China, was successfully launched on 15 September 2016, and its measurements of scattered photons of sunlight along the ...
Song Liu, Xuemei Zong, Congcong Qiao, Daren Lyu, Wenxing Zhang, Jinqiang Zhang, Hailei Liu, Minzheng Duan   +7 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Water Vapor Characteristics of Extreme Precipitation in Yingjiang, the “Rain Pole” of Mainland China

Applied Sciences
In the Yingjiang area of western Yunnan, precipitation is high throughout the year, making it one of the regions with the highest annual precipitation in mainland China.
Jin Luo, Liyan Xie, Weimin Wang, Yunchang Cao, Hong Liang, Yizhu Wang, Balin Xu   +6 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Development of Side Bidirectional Leader and Its Effect on Channel Branching of the Progressing Positive Leader of Lightning

Geophysical Research Letters, 2019
Fine time‐resolved images of the development of lightning bidirectional leaders below the cloud base were captured by a high‐speed camera in association with multiband electromagnetic field measurements.
Shanfeng Yuan, Rubin Jiang, Xiushu Qie, Zhuling Sun, Dongfang Wang, Abhay Srivastava   +5 more
doaj   +1 more source