Results 61 to 70 of about 5,065,100 (341)
This study presents a 2014 high-resolution spatially disaggregated emission inventory (0.025° × 0.025° horizontal resolution), of the main activities in the energy sector in Argentina.
S. Enrique Puliafito +3 more
doaj +1 more source
. While stand alone satellite and model aerosol products see wide utilization, there is a significant need in numerous atmospheric and climate applications for a fused product on a regular grid.
P. Lynch +13 more
semanticscholar +1 more source
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
The Pierre Auger Observatory is the largest operating cosmic ray observatory ever built. Calorimetric measurements of extensive air showers induced by cosmic rays are performed with a fluorescence detector.
+7 more
core +3 more sources
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
The cochaperone BAG3 promotes the stabilization of p53 under heat stress conditions
Under heat stress, BAG3 translocates to the nucleus and forms a complex with Hsp70 and p53, thereby promoting p53 stabilization and enhancing its transcriptional activity. These findings suggest that BAG3 functions as a cochaperone that supports p53‐mediated stress responses in cooperation with Hsp70.
Ngoc Nguyen Thi Minh +2 more
wiley +1 more source
Bahía Culebra se locoaliza en la parte norte de la costa Pacífica de Costa Rica. Es una región de afloramiento estacional, rica en ambientes y organismos marinos, y además, la zona de mayor desarrollo turístico del país. En este trabajo compilo y analizo
Jorge Cortés
doaj
Preface: 6th International Electronic Conference on Atmospheric Sciences
The sixth International Electronic Conference on Atmospheric Sciences, the range of topics will remain more general, but we are open to subject areas with a thematic topic of importance, especially interdisciplinary or transdisciplinary science [...]
Anthony R. Lupo
doaj +1 more source
THE OVERVIEW OF THE PLANETARY ATMOSPHERIC SPECTRAL TELESCOPE (PAST) IN THE SCIENTIFIC EXPERIMENTAL SYSTEM IN NEAR-SPACE (SENSE) [PDF]
To investigate mass transport and energy dissipation in space environments for solar system planet, a balloon-borne planetary atmospheric spectral telescope (PAST) is designed with 0.8-m aperture in spectral range from 280 nm to 680 nm will
Q. Meng +6 more
doaj +1 more source
Subcutaneous implantation of murine Panc02 pancreatic cancer cells depleted of sST2, a soluble decoy receptor for the proinflammatory interleukin‐33 (IL‐33), leads to a decreased number of GLUT4‐positive cancer‐associated adipocytes, reduced levels of the anti‐inflammatory molecule adiponectin, increased phosphorylation of IκBα, elevated Cxcl3 ...
Miho Akimoto +5 more
wiley +1 more source

