Results 51 to 60 of about 10,265 (249)
MicroRNA-10a-5p regulates macrophage polarization and promotes therapeutic adipose tissue remodeling
Molecular Metabolism, 2019 Objective: This study investigated the role of microRNAs generated from adipose tissue macrophages (ATMs) during adipose tissue remodeling induced by pharmacological and nutritional stimuli. Methods: Macrophage-specific Dicer knockout (KO) mice were used
Yoon Keun Cho +10 more
doaj +1 more source
My Invited Talk at ATMS 2022 India
, 2022 My Invited Talk at ATMS 2022 India https://youtu.be ...
Hadi Aliakbarian (14050494)
core +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
International Journal of Electrochemical Science, 2015 Arc thermal metal spraying method () provides proven long term protective coating systems using zinc, aluminum and their alloys for steel structure in a marine environment. This paper focused on studying the effect of spraying metal type, and presence or
Hong-Bok Choe +3 more
doaj +1 more source
Cell Death and Disease, 2021 Activation of adipose tissue macrophages (ATMs) contributes to chronic inflammation and insulin resistance in obesity. However, the transcriptional regulatory machinery involved in ATM activation during the development of obesity is not fully understood.
Ren-Dong Hu +13 more
doaj +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Impacts of Assimilating ATMS Radiances on Heavy Rainfall Forecast in RMAPS-ST
Remote Sensing, 2020 The Advanced Technology Microwave Sounder (ATMS) mounted on the Suomi National Polar-Orbiting Partnership (NPP) satellite can provide both temperature and humidity information for a weather prediction model.
Yanhui Xie +5 more
doaj +1 more source
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
EGFR-mediated activation of adipose tissue macrophages promotes obesity and insulin resistance
Nature Communications, 2022 In obesity, adipose tissue is chronically inflamed, leading to insulin resistance, and adipose tissue macrophages (ATMs) are a major source of cytokines that aggravate adipocyte dysfunction. Here, the authors show that selective deletion of the epidermal
Shirong Cao +11 more
doaj +1 more source