ATNC: Versatile Nanobody Chimeras for Autophagic Degradation of Intracellular Unligandable and Undruggable Proteins. [PDF]
J Am Chem Soc, 2023 Targeted protein degradation (TPD) through the autophagy pathway displays broad substrate scope and is gaining increasing interest in biology and medicine.
He H, Zhou C, Chen X.
europepmc +3 more sources
Genetic Variability Impacts Genotoxic and Transcriptome Responses in the Human Colon after the Consumption of Processed Red Meat Products and Those with Added Phytochemical Extracts. [PDF]
NutrientsThe PHYTOME study investigated the effect of consuming processed meat products on outcomes related to colorectal cancer risk without testing the impact of genetic variability on these responses.
DeBenedictis JN +4 more
europepmc +2 more sources
Consumption of Nitrate-Rich Beetroot Juice with or without Vitamin C Supplementation Increases the Excretion of Urinary Nitrate, Nitrite, and N-nitroso Compounds in Humans. [PDF]
Int J Mol Sci, 2019 Consumption of nitrate-rich beetroot juice (BRJ) by athletes induces a number of beneficial physiological health effects, which are linked to the formation of nitric oxide (NO) from nitrate. However, following a secondary pathway, NO may also lead to the
Berends JE +11 more
europepmc +2 more sources
Non-volatile N-nitrosamines in brewing industry. Part 1. - Arrising and methods of estimation.
Kvasný průmysl, 2012 Contrary to volatile N-nitrosamines, about representatives and mechanism of arrising of non-volatile nitrosamines in brewing industry is known only a little.
Jiří ČULÍK +3 more
doaj +1 more source
Geofluids, Volume 2020, Issue 1, 2020., 2020 The Luan River catchment within the North China plain has been famous for the development of its iron mineral resources since the 1950s. At the same time, it is also the main grain‐producing area, known as the granary of eastern Hebei Province. Groundwater plays an important role in this region, and thus, it is imperative for us to improve our ...
Yu Liu, Rong Ma, Marco Petitta
wiley +1 more source
Monitoring of potential contaminants in beer from the Czech Republic
Kvasný průmysl, 2019 The health safety of beer is still a discussed topic. In the Czech Republic, there is a well-developed system for controlling the content of potential beer contaminants, which are regularly attended by a number of large and medium-sized breweries and are
Jana Olšovská +5 more
doaj +1 more source
Real-Time Implementation of an Optimal Transient Neurocontroller for a GCSC [PDF]
, 2006 This paper presents the design of an optimal auxiliary transient neurocontroller (ATNC) for the gate controlled series capacitor (GCSC) in a multi-machine power system. GCSC is a recent advancement in the family of series FACTS devices.
Venayagamoorthy, G. K. +5 more
core +1 more source
Calcium-independent activation of skeletal muscle fibers by a modified form of cardiac troponin C [PDF]
, 1993 A conformational change accompanying Ca2+ binding to troponin C (TnC) constitutes the initial event in contractile regulation of vertebrate striated muscle. We replaced endogenous TnC in single skinned fibers from rabbit psoas muscle with a modified form
Kushmerick, M.J. +5 more
core +1 more source
Unloaded shortening of skinned muscle fibers from rabbit activated with and without Ca2+ [PDF]
, 1994 Unloaded shortening velocity (VUS) was determined by the slack method and measured at both maximal and submaximal levels of activation in glycerinated fibers from rabbit psoas muscle. Graded activation was achieved by two methods.
Kushmerick, M.J. +5 more
core +1 more source
Isometric force redevelopment of skinned muscle fibers from rabbit activated with and without Ca2+ [PDF]
, 1994 Fiber isometric tension redevelopment rate (kTR) was measured during submaximal and maximal activations in glycerinated fibers from rabbit psoas muscle.
Chase, P.B., Hannon, J.D., Martyn, D.A.
core +1 more source