Adversarial Threshold Neural Computer for Molecular de Novo Design [PDF]
In this article, we propose the deep neural network Adversarial Threshold Neural Computer (ATNC). The ATNC model is intended for the de novo design of novel small-molecule organic structures.
Evgeny Putin (2575033) +6 more
core +1 more source
Calcium-independent activation of skeletal muscle fibers by a modified form of cardiac troponin C [PDF]
A conformational change accompanying Ca2+ binding to troponin C (TnC) constitutes the initial event in contractile regulation of vertebrate striated muscle. We replaced endogenous TnC in single skinned fibers from rabbit psoas muscle with a modified form
Kushmerick, M.J. +5 more
core +1 more source
Unloaded shortening of skinned muscle fibers from rabbit activated with and without Ca2+ [PDF]
Unloaded shortening velocity (VUS) was determined by the slack method and measured at both maximal and submaximal levels of activation in glycerinated fibers from rabbit psoas muscle. Graded activation was achieved by two methods.
Kushmerick, M.J. +5 more
core +1 more source
A method for the investigation of free and protein-bound N-nitrosoproline in beer [PDF]
Hydrolysis of beer peptides and proteins by both mild enzymatic and vigorous alkaline conditions has established that peptide-bound N-nitrosoproline residues are not present in beer in significant quantities. Free N-nitrosoproline remains the single most
Johnson, P. +5 more
core +1 more source
Isometric force redevelopment of skinned muscle fibers from rabbit activated with and without Ca2+ [PDF]
Fiber isometric tension redevelopment rate (kTR) was measured during submaximal and maximal activations in glycerinated fibers from rabbit psoas muscle.
Chase, P.B., Hannon, J.D., Martyn, D.A.
core +1 more source
Inulin-fortification of a processed meat product attenuates formation of nitroso compounds in the gut of healthy rats [PDF]
Intake of red and processed meat has been suspected to increase colorectal cancer risk potentially via endogenous formation of carcinogenic N-nitroso compounds or increased lipid and protein oxidation.
Kuhnle, Gunter +10 more
core +1 more source
Study on Noise Prediction Model and Control Schemes for Substation
With the government’s emphasis on environmental issues of power transmission and transformation project, noise pollution has become a prominent problem now. The noise from the working transformer, reactor, and other electrical equipment in the substation will bring negative effect to the ambient environment.
Chuanmin Chen +4 more
wiley +1 more source
Close Vicinity of PrP Expressing Cells (FDC) with Noradrenergic Fibers in Healthy Sheep Spleen
In naturally and experimentally occurring scrapie in sheep, prions invade the immune system and replicate in lymphoid organs. Here we analysed immunohistochemically, in seven spleens of 6‐month‐old healthy sheep, the nature of the cells expressing prion protein (PrP) potentially supporting prion replication, as well as their relationship with autonomic
A. Bencsik +3 more
wiley +1 more source
Risque de transmission post-mortem de maladies infectieuses : revue systématique [PDF]
Introduction : la manipulation de cadavres peut comporter un risque infectieux, notamment durant une autopsie ou la pratique de soins de conservation.
Geoffray, Lauriane
core
Variability in fecal water genotoxicity, determined using the Comet assay, is independent of endogenous N-nitroso compound formation attributed to red meat consumption [PDF]
Red meat consumption causes a dose-dependent increase in fecal apparent total N-nitroso compounds (ATNC). The genotoxic effects of these ATNCs were investigated using two different Comet assay protocols to determine the genotoxicity of fecal water ...
Amanda J. Cross +9 more
core +1 more source

