Results 21 to 30 of about 383 (155)

Development of a model‐based clinical trial simulation platform to optimize the design of clinical trials for Duchenne muscular dystrophy

CPT: Pharmacometrics &Systems Pharmacology, Volume 11, Issue 3, Page 318-332, March 2022., 2022
Abstract Early clinical trials of therapies to treat Duchenne muscular dystrophy (DMD), a fatal genetic X‐linked pediatric disease, have been designed based on the limited understanding of natural disease progression and variability in clinical measures over different stages of the continuum of the disease. The objective was to inform the design of DMD
Karthik Lingineni, Varun Aggarwal, Juan Francisco Morales, Daniela J. Conrado, Diane Corey, Camille Vong, Jackson Burton, Jane Larkindale, Klaus Romero, Stephan Schmidt, Sarah Kim, the Cooperative International Neuromuscular Research Group investigators and Duchenne Regulatory Science Consortium members, C McDonald, E Henricson, M Cregan, L Johnson, J Han, N Joyce, A Nicorici, D Reddy, J Mah, A Chiu, T Haig, M Harris, M Kornelsen, N Rincon, K Sanchez, L Walker, M Tulinius, A Alhander, A Ekstrom, A Gustafsson, A Kroksmark, U Sterky, L Wahlgren, R Leshner, N Brody, B Drogo, M Leach, C Tesi‐Rocha, M Birkmeier, B Tadese, A Toles,, M Thangarajh, A Kornberg, K Carroll, K DeValle, R Kennedy, V Rodriguez, D Villano, Y Nevo, R Adani, A BarLeve, L Chen‐Joseph, M Daana, V Panteleyev‐Yitshak, E Simchovitz, D Yaffe, L Andreone, F Bonaudo, J Corderi, L Levi, L Mesa, P Marco, P Clemens, H Abdel‐Hamid, R Bendixen, C Bise, A Craig, K Karnavas, C Matthews, G Niizawa, A Smith, J Weimer, J Anger, T Christenson, J Florence, R Gadeken, P Golumbak, B Malkus, A Pestronk, R Renna, J Schierbecker, C Seiner, C Wulf, J Teasley, S Blair, B Grillo, E Monasterio, T Bertorini, M Barrett‐Adair, C Benzel, K Carter, J Clift, B Gatlin, R Henegar, J Holloway, M Igarashi, F Kiphut, A Parker, A Phillips, R Young, K North, K Cornett, N Gabriel, M Harman, C Miller, K Rose, S Wicks, H Kolski, L Chen, C Kennedy, M Beneggi, L Capone, A Molteni, V Morettini, T Lotze, A Gupta, A Knight, B Lott, R McNeil, G Orozco, R Schlosser, G Chambers, J Day, J Dalton, A Erickson, M Margolis, J Marsh, C Naughton, K Coleman‐Wood, A Hoffman, W Korn‐Petersen, N Kuntz, B Deliz, S Espada, P Fuste, C Luciano, J Torres, Lauren Morgenroth, M Ahmed, A Arrieta, N Bartley, T Brown‐Caines, C Carty, T Duong, J Feng, F Hu, L Hunegs, Z Sund, W Tang, A Zimmerman, Glen Nuckolls, Emily Carifi   +153 more
wiley   +1 more source

Pinole, un alimento tradicional mexicano con valor nutrimental

Tecnociencia Chihuahua, 2022
El pinole es un alimento de origen prehispánico que se obtiene principalmente a partir del tostado de los granos enteros de maíz y su posterior molienda.
Miguel Ángel Sánchez Madrigal, Dr. Armando Quintero-Ramos, Dra. Jazmín L. Tobías Espinoza, Dra. Carmen O. Meléndez Pizarro   +3 more
doaj   +1 more source

Current Insights into Phytochemistry, Nutritional, and Pharmacological Properties of Prosopis Plants

Evidence-Based Complementary and Alternative Medicine, Volume 2022, Issue 1, 2022., 2022
Prosopis is a regional cash crop that is widely grown in arid, semiarid, tropical, and subtropical areas. Compared with other legume plants, Prosopis is underutilized and has great potentialities. Prosopis not only is a good source of timber, construction, fencing material, and gum, but also can be applied for food, beverage, feed, and medicine ...
Jianshu Zhong, Peiyao Lu, Hanjing Wu, Ziyao Liu, Javad Sharifi-Rad, William N. Setzer, Hafiz A.R. Suleria, Hicham Harhar   +7 more
wiley   +1 more source

Effects of vitamin and mineral supplementation during pregnancy on maternal, birth, child health and development outcomes in low‐ and middle‐income countries: A systematic review

Campbell Systematic Reviews, Volume 17, Issue 2, June 2021., 2021
Abstract Background Almost two billion people who are deficient in vitamins and minerals are women and children in low‐ and middle‐income countries (LMIC). These deficiencies are worsened during pregnancy due to increased energy and nutritional demands, causing adverse outcomes in mother and child.
Emily C. Keats, Christina Oh, Tamara Chau, Dina S. Khalifa, Aamer Imdad, Zulfiqar A. Bhutta   +5 more
wiley   +1 more source

Comparative Evaluation of Three-dimensional Skeletal and Dentoalveolar Effects of Sawangi Flexiforce Expander and NiTi Expander in Class II (vertical) Cases with Maxillary Constriction: A Research Protocol [PDF]

Journal of Clinical and Diagnostic Research
Introduction: Maxillary constriction is a very common type of malocclusion found at any age. It is recommended to treat it as early as possible to avoid the worsening of the situation and to re-establish optimal function and aesthetics.
Srushti Atole, Ranjit Kamble
doaj   +1 more source

Exposure to improved nutrition from conception to age 2 years and adult cardiometabolic disease risk: a modelling study

The Lancet Global Health, 2018
Summary: Background: Low-income and middle-income countries with populations that are chronically undernourished in early life are undergoing a nutrition transition and are experiencing an epidemic of cardiometabolic disease.
Nicole D Ford, PhD, Jere R Behrman, PhD, John F Hoddinott, DPhil, John A Maluccio, PhD, Reynaldo Martorell, PhD, Manuel Ramirez-Zea, PhD, Aryeh D Stein, PhD   +6 more
doaj   +1 more source

Extrapolating Bypass Protein Potential of Treated Soybean Meal by Degradation in Rumen-Fistulated Brahman Cattle

Annals of Tropical Research, 2014
Loss of dietary proteins through microbial fermentation in the rumen may deprive the ruminant animals of valuable supply of amino acids at the intestinal level.
Angelo Francis F. Atole, Lolito C. Bestil   +1 more
doaj   +1 more source

Extrapolating the bypass potential of treated Madre de agua (Trichanthera gigantea Nees) leaf meal as protein source in Rumen-Fistulated Brahman Cattle

Annals of Tropical Research, 2019
This study assessed the effectiveness of formaldehyde, heat, and tannic acid treatments of madre de agua leaf meal (MALM) in reducing the degradation of dry matter (DMD) and crude protein (CPD) in the rumen for increased supply of bypass protein at the ...
Angelo Francis F. Atole, Lolito C. Bestil   +1 more
doaj   +1 more source

Evanescencias en las traducciones del Chilam Balam de Chumayel: el maíz y el frijol del Sur, los ibes del Oriente y el pozol ritual

Estudios de Cultura Maya, 2015
Este trabajo intenta restituir a las traducciones del maya el sentido original de algunos párrafos de la primera página del Chilam Balam de Chumayel, que fueron alterados en algunas ediciones de este libro.
Miguel Mauricio Vassallo Rodríguez
doaj   +1 more source

Chemical Composition and In Situ Digestibility of Common Feed Resources for Ruminants in Marginal Uplands

Annals of Tropical Research, 2014
This study assessed the chemical composition and in situ degradation of predominant feed resources for ruminants in the marginal uplands of Inopacan, Leyte, Philippines.
Lolito C. Bestil, Angelo Francis F. Atole, Jandells M. Rama   +2 more
doaj   +1 more source