Results 61 to 70 of about 795,106 (297)

Generation and detection of a sub-Poissonian atom number distribution in a one-dimensional optical lattice

, 2014
We demonstrate preparation and detection of an atom number distribution in a one-dimensional atomic lattice with the variance $-14$ dB below the Poissonian noise level.
Appel, J., Bookjans, E., Béguin, J. -B., Christensen, S. L., Müller, J. H., Polzik, E. S., Sørensen, H. L.   +6 more
core   +1 more source

Decrypting cancer's spatial code: from single cells to tissue niches

Molecular Oncology, EarlyView.
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik, Shi Pan, Eloise Withnell, Hou Wang Lam, Maria Secrier   +4 more
wiley   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

Developing an Integrated Model of Resilience and System Dynamics for NPP Accident [PDF]

Journal of Systems Thinking in Practice
The Fukushima Daiichi nuclear power plant (FDNPP) accident highlights the role of resilience and system dynamics in maintaining the safety of nuclear power plants (NPP).
Muhammed Mufazzal Hossen
doaj   +1 more source

A Review of Recent Developments in Atomic Processes for Divertors and Edge Plasmas

, 1995
The most promising concepts for power and particle control in tokamaks and other fusion experiments rely upon atomic processes to transfer the power and momentum from the edge plasma to the plasma chamber walls. This places a new emphasis on processes at
Afrosimov, Akiba, Allen, Anders, Bacal, Bachmann, Badnell, Badnell, Barnett, Bates, Bell, Bitter, Bonnin, Botero, Burgess, Cacciatore, Clark, D.E. Post, Djuric, Dolder, Dunn, Ehrhardt, Fonck, Grossman, Haas, Harrision, Herrman, Hiskes, Hiskes, Hogan, Hogan, Hulse, Hulse, Hulse, Hutchinson, Isler, Ito, Janeschitz, Janeschitz, Janev, Janev, Janev, Jensen, Jensen, Kato, Klepper, Krasheninnikov, Lackner, Lengyel, Lotz, Mahdavi, Marchand, Nagami, Neuhauser, Ogden, Petravic, Petrie, Petrie, Phaneuf, Phaneuf, Pindzola, Pindzola, Poschenrieder, Post, Post, Post, Rebut, Rebut, Reiter, Roth, Roth, Ruzic, Scott, Shimada, Stangeby, Summers, Tawara, Tawara, v. Emmichoven, v. Hellerman, Wahlin, Wan, Watkins, Weisheit, Wiese, Wiese, Wolf   +86 more
core   +1 more source

Characterizing epithelial‐mesenchymal transition‐linked heterogeneity in breast cancer circulating tumor cells at a single‐cell level

Molecular Oncology, EarlyView.
In over 50% of non‐metastatic breast cancer patients, circulating tumor cells (CTCs) along the whole epithelial‐mesenchymal transition spectrum are detected. Total CTC number and individual phenotypes relate to aggressive disease characteristics, including lymph node involvement and higher tumor proliferation. At the single‐cell level, mesenchymal CTCs
Justyna Topa, Julia Richert, Tomasz Stokowy, Alicja Staśczak, Mariusz Szajewski, Maciej Ciesielski, Petra M. Grešner, Bartłomiej Tomasik, Łukasz Arcimowicz, Agnieszka Stankiewicz, Grażyna Suchodolska, Elżbieta Senkus, Wiesław Kruszewski, Anna J. Żaczek, Aleksandra Markiewicz   +14 more
wiley   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Investigations on strength of piping for non-condensable gas combustion (Part 2: FEM analysis of steel pipes with a valve or an elbow subjected to hydrogen-oxygen detonation)

Nihon Kikai Gakkai ronbunshu, 2015
Carbon steel pipe specimens, which had been experimentally ruptured or deformed by hydrogen-oxygen detonation, were analysed by dynamic analysis using a finite element method (FEM).
Akira NEBU, Koji YAMADA, Koji DOZAKI, Akitaka HIDAKA, Masahiro UCHIDA, Takahiro SONE   +5 more
doaj   +1 more source

High LRIG1 expression predicts lymph node metastasis in patients with uterine cervical cancer

FEBS Open Bio, EarlyView.
Lymph node status is crucial in determining treatment for women with early‐stage cervical cancer. We demonstrate that high LRIG1 protein expression in primary tumors can predict lymph node metastases. Our findings support further investigation of LRIG1 as a biomarker to improve staging accuracy and guide treatment decisions in cervical cancer patients.
Pernilla Israelsson, Lisa Lif, Husam Oda, Alexandra Lorenzzi de Melo, David Lindquist, Håkan Hedman   +5 more
wiley   +1 more source

Analysis of Steam Line Break Accident Using PCTRAN Model of VVER-1200 NPP

Applications of Modelling and Simulation, 2023
The investigation of thermal-hydraulic parameters during steam-line break (SLB) accidents is performed by applying the personal computer transient analyzer (PCTRAN) simulator model of the VVER-1200 nuclear power plant (NPP). Five cases, namely, 0.005 m2 (
Muhammed Mufazzal Hossen, M. Khalaquzzaman, S. K. Anisur Rahman   +2 more
doaj