Results 121 to 130 of about 105,814 (267)

Pathogenesis of Age‐Related Hearing Loss and Therapeutic Strategies

open access: yesSensory Neuroscience, EarlyView.
ABSTRACT Age‐related hearing loss (ARHL) is a degenerative disorder of the auditory system, characterized by bilateral symmetrical sensorineural hearing loss that occurs with aging. As a highly prevalent age‐related condition worldwide, ARHL significantly impairs both the quality of life and mental health of the elderly.
Yu Xiao   +6 more
wiley   +1 more source

Towards the Application of Atorvastatin to Intensify Proapoptotic Potential of Conventional Antileukemic Agents In Vitro [PDF]

open access: yes, 2015
It has been previously revealed that statins used at high concentrations display antileukemic potential towards chronic lymphocytic leukemia (CLL) cells.
Błoński, Jerzy Z.   +9 more
core   +3 more sources

The Effect of Statins on Carotid Intima-Mdia Thickness in patients Who had ACS [PDF]

open access: yes
Background : Statins have been established by definitive primary and secondary cardiovascular prevention trials as the cornerstone of pharmacoprevention of atherosclerotic vascular disease. Carotid arterial intima-media thickness is used as a noninvasive
حسینی, زهرا   +2 more
core  

Assessing the effect of statins in lowering the risk of stroke and preventing cerebral ischemia in patients with hypercholesterolemia [PDF]

open access: yes, 2017
Numerous analyses have explored the role of statins in reducing stroke incidence, reducing cerebral ischemia in hypercholesterolemic patients, and preventing ischemic stroke.
AlSulaiman, Wafa
core  

Statin use and adverse effects among adults \u3e 75 years of age: Insights from the Patient and Provider Assessment of Lipid Management (PALM) registry [PDF]

open access: yes, 2018
Background: Current statin use and symptoms among older adults in routine community practice have not been well characterized since the release of the 2013 American College of Cardiology/American Heart Association guideline.
Goldberg, Anne C   +10 more
core   +2 more sources

Effects of losartan and atorvastatin on the development of early posttraumatic joint stiffness in a rat model

open access: yesDrug Design, Development and Therapy, 2019
Background After a trauma, exuberant tissue healing with fibrosis of the joint capsule can lead to posttraumatic joint stiffness (PTJS). Losartan and atorvastatin have both shown their antifibrotic effects in different organ systems.
A. Baranowski   +10 more
semanticscholar   +1 more source

Catalytic Scalable Synthesis of Polyketides Enabled by Chiral Brønsted Acid‐Catalyzed Asymmetric Allylborations

open access: yesThe Chemical Record, EarlyView.
The scalable synthesis of target molecules is crucial for applications such as biological evaluation in medicinal chemistry and even industrial production. We described recent advances in chiral Brønsted acid–catalyzed asymmetric allylboration, which enables access to previously elusive chiral building blocks, and highlight its application to the ...
Shigenobu Umemiya, Masahiro Terada
wiley   +1 more source

Optimized zein nanospheres for improved oral bioavailability of atorvastatin

open access: yesInternational Journal of Nanomedicine, 2015
Fahima M Hashem,1 Majid M Al-Sawahli,2 Mohamed Nasr,1 Osama AA Ahmed3,4 1Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Helwan University, Cairo, 2Holding Company for Biological Products and Vaccines, Giza, Egypt; 3Department ...
Hashem FM   +3 more
doaj  

Recurrent Symptomatic Hemorrhage in Cerebral Cavernous Malformations After Discontinuation of Atorvastatin or Placebo

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background A recent randomized prospective controlled trial demonstrated that atorvastatin for up to 2 years was safe but did not significantly alter rebleeding in cerebral cavernous malformations.
Bader Ali   +13 more
doaj   +1 more source

SDF-1α upregulation by atorvastatin in rats with acute myocardial infarction via nitric oxide production confers anti-inflammatory and anti-apoptotic effects

open access: yesJournal of Biomedical Science, 2012
Background The effects of atorvastatin on SDF-1α expression under acute myocardial infarction (AMI) are still unclear. Therefore, our present study is to investigate the roles and mechanisms of atorvastatin treatment on SDF-1α expression in rats with AMI.
Qiu Ruofeng   +9 more
doaj   +1 more source

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