Results 111 to 120 of about 51,731 (234)

Maternal nutrition as a key determinant of placental and developing blood–brain barrier xenobiotic protective functions

The Journal of Physiology, EarlyView.
Abstract figure legend Suboptimal maternal nutrition alters placental and developing blood–brain barrier (BBB) protective function and is associated with increased fetal brain vulnerability. In the placenta, nutritional adversity may reduce the exchange surface area and promote meta‐inflammation, compromising barrier efficiency in a model‐ and context ...
Kristin L. Connor, Nycolle I. S. Souza, Bruno G. Anjos, Stephen G. Matthews, Enrrico Bloise   +4 more
wiley   +1 more source

Effect of atorvastatin 1% mouthwash in the prevention of radiotherapy induced mucositis: A pilot study

Caspian Journal of Internal Medicine, 2022
Background: Oral mucositis is a troublesome symptom for people who receive radiotherapy and chemotherapy and it is a dose-dependent factor. Atorvastatin is a HMG-CoA reductase inhibitors and various studies have proven its anti-inflammatory effects.
Shahram Ala, Majid Saeedi, Arash Ghasemi, Melika Namdari, Neda Koulaeinejad   +4 more
doaj  

The Blue Delirium: Serotonin and Anticholinergic Toxicity in a 95‐Year‐Old Woman

Journal of the American Geriatrics Society, EarlyView.
Camila S. Badell, Kathleen Brodowski, Eloy F. Ruiz, Eric Tien Yen Chyn   +3 more
wiley   +1 more source

Dual pharmacological targeting of coactivator‐associated arginine methyltransferase 1 (CARM1) and salt inducible kinase (SIK) drives ketogenesis in both hepatocytes and mice

British Journal of Pharmacology, Volume 183, Issue 15, Page 4399-4415, August 2026.
Abstract Background and Purpose Ketone bodies are liver‐derived circulating energy metabolites that positively impact most hallmarks of ageing. Ketone bodies increase during calorie restriction and fasting, two of the more widely perceived methods to increase health span.
Tábata Bergonci, Troels Kjær Rosenbæk, Samuel J. Windross, Ulrik B. Keiding, Estéfano Pinilla, Katrine P. Stuckert, Jakob Hansen, Camilla B. Nielsen, Jemila Peter Gomes, Lucy R. Davies, Johan Palmfeldt, Volker Loeschcke, Charlotte U. Andersen, Ulf Simonsen, Thomas B. Poulsen, Mogens Johannsen   +15 more
wiley   +1 more source

Atorvastatin Induced Erythrocytes Membrane Blebbing

Dose-Response, 2019
Atorvastatin, an inhibitor of 3-hydroxy-3-methylglutaryl-coenzymeA reductase, is usually used for the treatment of hypercholesterolemia. Besides its pharmacological and side actions, its toxic effects on human nucleus devoid of erythrocytes are still ...
Rumaisa Bashir Rana, Kashif Jilani, Muhammad Shahid, Muhammad Riaz, Mazhar Hussain Ranjha, Ismat Bibi, Asma Asghar, Muhammad Irfan   +7 more
doaj   +1 more source

Porównanie intensywnego i standardowego obniżania stężenia lipidów za pomocą atorwastatyny u chorych z dyslipidemią cukrzycową Badanie DALI - podwójnie ślepa, randomizowana próba kliniczna kontrolowana placebo, przeprowadzona u chorych na cukrzycę typu 2 i dyslipidemię cukrzycową

, 2002
INTRODUCTION. In patients with type 2 diabetes, intensive glucose regulation, although effective for microangiopathy, has not been shown to have unambiguous preventive effects on the occurrence of cardiovascular disease.
Intervention, Diabetes Atorvastatin Lipid
core   +1 more source

A comparative study of efficacy of atorvastatin, rosuvastatin, and atorvastatin + fibrates as lipid lowering agents

, 2017
Background: Hypercholesterolemia patients are at high risk of coronary heart disease. National cholesterol education programme (NCEP) Adult Treatment Panel III guidelines provide the option of aggressively lowering Low-density cholesterol in them ...
Vadlamannati, Yamini, Nagarur, Karunasree, Raja, Narasimha Rao   +2 more
core   +2 more sources

Atorvastatin blocks Sonic Hedgehog medulloblastoma progression through apoptosis

, 2017
Aberrant activation of Sonic Hedgehog signaling transduction leads to formation of numerous malignancies, including medulloblastoma (MB) – the most common malignant pediatric tumor.
Z.I. Abramova, R.E. Gordon
core  

Effect of atorvastatin on phagocytosis of the blue mussels, Mytilus edulis

, 2019
Increasing concentration of biologically active pharmaceutical compounds can affect marine organisms. The bioavailability and environmental stability of these compounds make them potential threat to these organisms, specially the sessile organisms.
Sabrina Glufke (7884569), Udo Kragl (7884563), Stock, Marius, Falfushynska, Halina, Ruth, Wolfgang, Sokolova, Inna M, Fouzia Haider (7883918), Wolfgang Ruth (2325415), Oppermann, Christina, Eileen J Winkel (7884572), Glufke, Sabrina, Marius Stock (7884566), Inna M Sokolova (7398920), Christina Oppermann (7884560), Winkel, Eileen J, Kragl, Udo, Haider, Fouzia, Eugene P Sokolov (7884557), Halina Falfushynska (7398923), Sokolov, Eugene P   +19 more
core   +1 more source

The changing epidemiology of human type 2 diabetes–associated atherosclerosis: Pathophysiological mechanisms and emerging treatment possibilities

Journal of Internal Medicine, Volume 300, Issue 2, Page 131-152, August 2026.
Abstract Type 2 diabetes (T2D) is a major global health concern strongly associated with atherosclerosis and subsequent macrovascular complications. These complications are the leading cause of death among T2D patients. Despite a decline in cardiovascular events over the last decade, individuals with T2D still have an approximately doubled risk ...
Dania Al‐Sharify, Jiangming Sun, Andreas Edsfeldt   +2 more
wiley   +1 more source