Results 121 to 130 of about 82,297 (250)

Is Atorvastatin Associated with New Onset Diabetes or Deterioration of Glycemic Control? Systematic Review Using Data from 1.9 Million Patients

open access: yesInternational Journal of Endocrinology, 2018
Background. Current evidence indicates that statins increase the risk of new onset diabetes mellitus (NOD) and also deteriorate the glycemic control in patients with known diabetes mellitus (DM) after high-dose statin therapy. Aims.
Angeliki M. Angelidi   +3 more
doaj   +1 more source

Novel and emerging antimicrobial strategies in the management of oral infections

open access: yesPeriodontology 2000, EarlyView.
Abstract Background Antibiotics marked a pivotal turning point in human civilization, enhancing social interactions and extending human life expectancy. In addition to their success in treating systemic infectious diseases, they have significantly improved periodontal treatment outcomes as an adjunct therapy.
Ozge Unlu, Nil Yakar, Alpdogan Kantarci
wiley   +1 more source

Correlation of atorvastatin with subjective memory deficits: a study from the NHANES and FAERS databases

open access: yesFrontiers in Neurology
BackgroundPost-marketing regulatory data suggest a potential association between atorvastatin use and memory protection; however, findings from observational studies have been inconsistent and remain a subject of controversy.ObjectiveThis study aims to ...
Hao Zhang, Hua Huang, Panli Zhao
doaj   +1 more source

The effects of uninterrupted and interrupted sitting on blood pressure and arterial stiffness in patients with established coronary heart disease

open access: yesExperimental Physiology, EarlyView.
Abstract Sedentary behaviour is an independent risk factor for cardiovascular disease. In healthy adults, prolonged uninterrupted sitting acutely increases blood pressure (BP) and aortic stiffness; however, these effects can be mitigated with light physical activity interruptions.
Simon Fryer   +7 more
wiley   +1 more source

Cardiac remodelling in type 2 diabetes: Pathophysiological mechanisms and opportunities for multiscale computational modelling and simulation

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Overview of multiscale cardiac remodelling in type 2 diabetes and how to model and simulate these changes using a human‐based, multiscale computational framework. Cardiac remodelling in type 2 diabetes occurs at ionic channel, protein, cellular, tissue and whole‐organ level, affecting the electrophysiological function, mechanical
Ambre Bertrand   +2 more
wiley   +1 more source

Evaluation of periodontal health in patients taking atorvastatin

open access: yesCaspian journal of dental research, 2018
Introduction: Periodontal disease as a chronic inflammatory condition is more prevalent in adults. Considering the anti-inflammatory effect of statins and the need to find out the effects of these drugs on the prevention and treatment of periodontal ...
Kosar Rezaei Talarposhti   +3 more
doaj  

Maternal nutrition as a key determinant of placental and developing blood–brain barrier xenobiotic protective functions

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Suboptimal maternal nutrition alters placental and developing blood–brain barrier (BBB) protective function and is associated with increased fetal brain vulnerability. In the placenta, nutritional adversity may reduce the exchange surface area and promote meta‐inflammation, compromising barrier efficiency in a model‐ and context ...
Kristin L. Connor   +4 more
wiley   +1 more source

Pharmacokinetic Drug–Drug Interaction Potential of Oral Anticancer Drugs

open access: yesClinical Pharmacology &Therapeutics, Volume 119, Issue 6, Page 1614-1627, June 2026.
Drug–drug interaction (DDI) management is critical for safe and effective use of oral anticancer drugs (OADs). Our study objectives were to (i) compile clinically relevant pharmacokinetic (PK) DDI mechanisms for OADs and (ii) assess the prevalence of PK potential DDIs (PDDIs) in patients with advanced solid cancers.
Fatimah Alhurayri   +10 more
wiley   +1 more source

The Blue Delirium: Serotonin and Anticholinergic Toxicity in a 95‐Year‐Old Woman

open access: yes
Journal of the American Geriatrics Society, EarlyView.
Camila S. Badell   +3 more
wiley   +1 more source

Molecular Quantification of Fibrogenesis and Macrophage Activation Associate With Clinical Worsening in Patients With Cirrhosis

open access: yesLiver International Communications, Volume 7, Issue 2, June 2026.
ABSTRACT Knowledge of the potential of biomarkers for monitoring clinical improvement, assessing trajectory or disease progression in advanced chronic liver disease is still insufficient. This study investigated biomarkers of fibrosis and macrophage activation over time in newly diagnosed patients with cirrhosis and their potential association with ...
Emilie Toft Skovgaard   +8 more
wiley   +1 more source

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