Results 141 to 150 of about 105,814 (267)

The role of Coenzyme Q10 in statin-associated myopathy [PDF]

open access: yes, 2009
Statins, or 3-hydroxyl-3-methylglutaryl coenzyme HMG-CoA reductase inhibitors,\ud are cholesterol-lowering drugs which are frequently used in the primary and secondary\ud prevention of coronary artery disease. Current research and recommendations support\
Kalra, Dr Sanjay
core  

High levels of serum cholesterol increase the risk of developing vessel co‐opting tumors in colorectal cancer liver metastases

open access: yesThe FEBS Journal, EarlyView.
High serum cholesterol is linked to colorectal cancer liver metastases (CRCLM) subtypes with poor survival (replacement pattern). Levels of cholesterol under 4 mmol·L−1 correlated with better survival and a desmoplastic pattern subtype. Furthermore, in vivo PCSK9 inhibitor evolocumab, which lowers cholesterol, reduced liver metastases.
Amatzia Gantz   +9 more
wiley   +1 more source

A Validated Reversed-Phase HPLC Method for the Determination of Atorvastatin Calcium in Tablets [PDF]

open access: yes, 2014
A Reversed-Phase Liquid Chromatographic (RP-LC) assay method was developed for the quantitative determination of atorvastatin calcium in the presence of its degradation products.
Ferello, L.   +5 more
core  

Reducing Medication‐Related Harm Through Home‐Based Primary Care

open access: yesJournal of the American Geriatrics Society, EarlyView.
This figure illustrates teaching strategies for the five domains of geriatric care, represented as the “5 M's”: Medication, Mentation, Mobility, Multi‐Complexity, and Matters Most. For each domain, Ms. T's clinical problems are listed with corresponding interventions.
Thomas J. Haferkamp   +2 more
wiley   +1 more source

Myasthenia gravis following the initiation of statin therapy: A multinational self‐controlled case series study

open access: yesJournal of Internal Medicine, EarlyView.
Abstract Background Evidence regarding the risk of new‐onset myasthenia gravis (MG) following statin therapy initiation is limited. Objectives To investigate this potential adverse effect using multinational real‐world population‐based data. Methods A self‐controlled case series (SCCS) study was conducted using electronic medical records and claims ...
Vincent Ka Chun Yan   +16 more
wiley   +1 more source

The reduced cost of providing a nationally recognised service for familial hypercholesterolaemia

open access: yes, 2014
OBJECTIVE: Familial hypercholesterolaemia (FH) affects 1 in 500 people in the UK population and is associated with premature morbidity and mortality from coronary heart disease.
Bacon, S.   +7 more
core   +1 more source

Parasomnias and sleep‐related movement disorders induced by drugs in the adult population: a review about iatrogenic medication effects

open access: yesJournal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary Parasomnias and sleep‐related movement disorders (SRMD) are major causes of sleep disorders and may be drug induced. The objective of this study was to conduct a systematic review of the literature to examine the association between drug use and the occurrence of parasomnias and SRMD.
Sylvain Dumont   +5 more
wiley   +1 more source

Correlation of atorvastatin with subjective memory deficits: a study from the NHANES and FAERS databases

open access: yesFrontiers in Neurology
BackgroundPost-marketing regulatory data suggest a potential association between atorvastatin use and memory protection; however, findings from observational studies have been inconsistent and remain a subject of controversy.ObjectiveThis study aims to ...
Hao Zhang, Hua Huang, Panli Zhao
doaj   +1 more source

Sleep characteristics and self‐reported sleep quality in the oldest‐old: Results from a prospective longitudinal cohort study

open access: yesJournal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary Little is known about the correlation between subjective perception and objective measures of sleep quality in particular in the oldest‐old. The aim of this study was to perform longitudinal home sleep monitoring in this age group, and to correlate results with self‐reported sleep quality.
Hugo Saner   +4 more
wiley   +1 more source

Is Atorvastatin Associated with New Onset Diabetes or Deterioration of Glycemic Control? Systematic Review Using Data from 1.9 Million Patients

open access: yesInternational Journal of Endocrinology, 2018
Background. Current evidence indicates that statins increase the risk of new onset diabetes mellitus (NOD) and also deteriorate the glycemic control in patients with known diabetes mellitus (DM) after high-dose statin therapy. Aims.
Angeliki M. Angelidi   +3 more
doaj   +1 more source

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