Results 71 to 80 of about 3,667 (197)

Atovaquone/Proguanil: The Need for Family Protection [PDF]

open access: yesJournal of Travel Medicine, 2006
An increasing number of families, including children and the elderly, are seeking more adventurous travel in exotic parts of the world. Holiday destinations now include once-remote regions such as subSaharan Africa and New Guinea. This increase in visits to tropical and subtropical regions, combined with widespread chloroquine-resistant malaria, now ...
openaire   +2 more sources

Characteristics and outcome of patients with malaria presented to a Hong Kong emergency department—A retrospective cohort analysis

open access: yesHong Kong Journal of Emergency Medicine, Volume 31, Issue 2, Page 66-75, April 2024.
In our study of 70 return travellers with malaria, emergency physicians successfully identified 34.3% of cases based on clinical features, while a further 27% were incidentally diagnosed through blood smear analysis. All patients reported to have fever.
Chi Yeung Yeung   +3 more
wiley   +1 more source

Malaria prevention in travelling children

open access: yesSouth African Family Practice, 2012
Preventing malaria in children is often neglected. Prevention is very important, as malaria is still a significant cause of childhood mortality. Parents must be aware that the same measures must be taken by children to avoid being bitten by mosquitoes ...
S. Mathijs
doaj   +1 more source

The Malaria Burden: A South African Perspective

open access: yesJournal of Tropical Medicine, Volume 2024, Issue 1, 2024.
Malaria is a deadly disease caused by protozoan pathogens of the Plasmodium parasite. Transmission to humans occurs through the bite of an infected female Anopheles mosquito. According to the World Health Organization (WHO), an estimated 247 million cases of malaria were recorded worldwide in 2021, with approximately 619 000 malaria deaths. The initial
Marissa Balmith   +3 more
wiley   +1 more source

A unique phosphatidylinositol 4-phosphate 5-kinase is activated by ADP-ribosylation factor in Plasmodium falciparum.

open access: yes, 2009
In eukaryotes, calcium signalling has been linked to hydrolysis of the phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P(2)). The final enzyme in the synthesis of this phosphoinositide, a Type I phosphatidylinositol 4-phosphate 5-kinase (PIP5K), is ...
Leber, Werner   +5 more
core   +1 more source

Myoglobin Cast Nephropathy Diagnosed on Renal Biopsy in a Patient Treated for Malarial Infection

open access: yesCase Reports in Nephrology, Volume 2024, Issue 1, 2024.
Myoglobin cast nephropathy occurs in cases of acute renal injury in which large amounts of myoglobin accumulate in the renal tubules, presenting as muscle pain, reddish‐brown urine, and elevated creatine kinase levels. Our case describes a 60‐year‐old male who came to the emergency department with fevers, mild abdominal pain, and constitutional ...
Ramya Varadarajan   +8 more
wiley   +1 more source

Optimisation of the atovaquone-proguanil treatment regime.

open access: yes, 2017
(a) Trophozoite stage parasites (strain K1) were treated with a 2-fold dose series of atovaquone (ATQ), proguanil (PG) or a constant-ratio combination of both drugs (ATQ+PG) for 48 hours.
Jon Deakin (3813211)   +4 more
core   +1 more source

Artemisinin Combination Therapy Can Result in Clinical Failure If Oral Therapy Is Not Directly Observed

open access: yesCanadian Journal of Infectious Diseases and Medical Microbiology, 2013
Intravenous artesunate therapy is the first-line therapy for severe malaria, and is highly efficacious when used in combination with an oral partner drug such as doxycycline or atovaquone-proguanil.
Wilson W Chan   +2 more
doaj   +1 more source

CalcuSyn output for the combination between atovaquone and proguanil.

open access: yes, 2017
CalcuSyn output for the combination between atovaquone and proguanil.
Jon Deakin (3813211)   +4 more
core   +1 more source

The pharmacokinetics of atovaquone and proguanil in pregnant women with acute falciparum malaria.

open access: yes, 2003
OBJECTIVE: To determine the pharmacokinetic properties of atovaquone, proguanil, and the triazine metabolite cycloguanil in women with recrudescent multi-drug resistant falciparum malaria during the second and third trimesters of pregnancy treated by ...
Gilveray, G   +9 more
core   +1 more source

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