Results 71 to 80 of about 3,499 (203)

Malaria and the traveller [PDF]

open access: yes, 2005
Malaria has reached epidemic proportions. About 40% of the world’s population live in malarious areas. It is estimated that 400 million people are infected by malaria each year and of these, 1-3 million die, mostly children under five years of age.
Tonna, Antonella, Tonna, Ivan
core  

The Effect of Malaria on Responses to Unrelated Vaccines in Animals and Humans: A Systematic Review and Meta‐Analysis

open access: yesParasite Immunology, Volume 46, Issue 10, October 2024.
ABSTRACT Vaccine efficacy varies globally, often showing reduced immune responses in low‐ and middle‐income countries, possibly due to the immunomodulatory effects of parasitic infections like malaria. This systematic review evaluates the impact of malaria on immune responses to unrelated vaccines in humans and animals.
Ludoviko Zirimenya   +6 more
wiley   +1 more source

Clinical pharmacology considerations and drug–drug interactions with long‐acting cabotegravir and rilpivirine relevant to sub‐Saharan Africa

open access: yesBritish Journal of Clinical Pharmacology, Volume 90, Issue 9, Page 2079-2091, September 2024.
Long‐acting injectable (LAI) cabotegravir and rilpivirine for HIV treatment and LAI cabotegravir for pre‐exposure HIV prophylaxis are being rolled out in a multitude of countries worldwide. Due to the prolonged exposure, it can be challenging to undertake ‘traditional’ pharmacokinetic studies and current guidance is derived from their oral equivalents ...
Adrian Steulet   +5 more
wiley   +1 more source

Artenimol–piperaquine in children with uncomplicated imported falciparum malaria: experience from a prospective cohort

open access: yesMalaria Journal, 2019
Background Although malaria remains one of the major public health threats in inter-tropical areas, there is limited understanding of imported malaria in children by paediatricians and emergency practitioners in non-endemic countries, often resulting in ...
Lauren Pull   +6 more
doaj   +1 more source

Malaria prevention in travelling children

open access: yesSouth African Family Practice, 2012
Preventing malaria in children is often neglected. Prevention is very important, as malaria is still a significant cause of childhood mortality. Parents must be aware that the same measures must be taken by children to avoid being bitten by mosquitoes ...
S. Mathijs
doaj   +1 more source

Acute acalculous cholecystitis due to Plasmodium falciparum malaria

open access: yesJournal of Pediatric Surgery Case Reports, 2020
Acalculous cholecystitis is a rare entity, typically only presenting in patients with chronic illness and other comorbidities. For this reason, it is very rare in children and upon diagnosis, efforts should be made to search for an underlying cause or ...
Madison Greer   +2 more
doaj   +1 more source

A Poisson hierarchical modelling approach to detecting copy number variation in sequence coverage data. [PDF]

open access: yes, 2013
BACKGROUND: The advent of next generation sequencing technology has accelerated efforts to map and catalogue copy number variation (CNV) in genomes of important micro-organisms for public health.
Assefa, Samuel A   +5 more
core   +1 more source

Drugs associated with epidermal necrolysis in children: A World Health Organization pharmacovigilance database analysis

open access: yesJournal of the European Academy of Dermatology and Venereology, Volume 38, Issue 9, Page 1791-1798, September 2024.
Abstract Background Stevens–Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are rare life‐threatening mucocutaneous reactions most often induced by drugs. To date, no large pharmacovigilance study has been conducted in the paediatric population.
Pauline Bataille   +6 more
wiley   +1 more source

Identification of Orthosteric and Allosteric Pharmacological Chaperones for Mucopolysaccharidosis Type IIIB

open access: yesChemBioChem, Volume 25, Issue 15, August 1, 2024.
We modeled substrate interactions in NAGLU′s active site and predicted allosteric sites. Virtual screening against a human‐tested molecule database identified potential pharmacological chaperones (PCs). In vitro evaluations confirmed their binding to NAGLU and ability to restore enzymatic activity in MPS IIIB fibroblasts with mutant enzymes.
Juan Camilo Losada   +6 more
wiley   +1 more source

Malaria in the Australian refugee population [PDF]

open access: yes, 2007
Copyright to Australian Family Physician. Reproduced with permission. Permission to reproduce must be sought from the publisher, The Royal Australian College of General Practitioners.Malaria is a serious health problem in many of the countries from which
Benson, J., Davis, J.
core  

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