Results 61 to 70 of about 3,667 (197)
Parasite Immunology, Volume 46, Issue 10, October 2024.ABSTRACT Vaccine efficacy varies globally, often showing reduced immune responses in low‐ and middle‐income countries, possibly due to the immunomodulatory effects of parasitic infections like malaria. This systematic review evaluates the impact of malaria on immune responses to unrelated vaccines in humans and animals.
Ludoviko Zirimenya +6 more
wiley +1 more source
British Journal of Clinical Pharmacology, Volume 90, Issue 9, Page 2079-2091, September 2024.Long‐acting injectable (LAI) cabotegravir and rilpivirine for HIV treatment and LAI cabotegravir for pre‐exposure HIV prophylaxis are being rolled out in a multitude of countries worldwide. Due to the prolonged exposure, it can be challenging to undertake ‘traditional’ pharmacokinetic studies and current guidance is derived from their oral equivalents ...
Adrian Steulet +5 more
wiley +1 more source
Medicines for the prevention of malaria while traveling - Atovaquone-proguanil (Malarone\u2122) [PDF]
Atovaquone-proguanil is a combination of two drugs, atovaquone and proguanil, in a single tablet. It is available in the United States by prescription only.
core +2 more sources
Malaria Journal, 2019 Background Although malaria remains one of the major public health threats in inter-tropical areas, there is limited understanding of imported malaria in children by paediatricians and emergency practitioners in non-endemic countries, often resulting in ...
Lauren Pull +6 more
doaj +1 more source
Acute acalculous cholecystitis due to Plasmodium falciparum malaria
Journal of Pediatric Surgery Case Reports, 2020 Acalculous cholecystitis is a rare entity, typically only presenting in patients with chronic illness and other comorbidities. For this reason, it is very rare in children and upon diagnosis, efforts should be made to search for an underlying cause or ...
Madison Greer +2 more
doaj +1 more source
Journal of the European Academy of Dermatology and Venereology, Volume 38, Issue 9, Page 1791-1798, September 2024.Abstract Background Stevens–Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are rare life‐threatening mucocutaneous reactions most often induced by drugs. To date, no large pharmacovigilance study has been conducted in the paediatric population.
Pauline Bataille +6 more
wiley +1 more source
Malaria Journal, 2012 Background Malaria continues to be amongst the most frequent infectious diseases imported to Europe. Whilst European treatment guidelines are based on data from studies carried out in endemic areas, there is a paucity of original prospective treatment ...
Bouchaud Olivier +18 more
doaj +1 more source
Investigating antimalarial drug interactions of emetine dihydrochloride hydrate using CalcuSyn-based interactivity calculations. [PDF]
PLoS ONE, 2017 The widespread introduction of artemisinin-based combination therapy has contributed to recent reductions in malaria mortality. Combination therapies have a range of advantages, including synergism, toxicity reduction, and delaying the onset of ...
Holly Matthews +4 more
doaj +1 more source
ChemBioChem, Volume 25, Issue 15, August 1, 2024.We modeled substrate interactions in NAGLU′s active site and predicted allosteric sites. Virtual screening against a human‐tested molecule database identified potential pharmacological chaperones (PCs). In vitro evaluations confirmed their binding to NAGLU and ability to restore enzymatic activity in MPS IIIB fibroblasts with mutant enzymes.
Juan Camilo Losada +6 more
wiley +1 more source
, 2004 Atovaquone-proguanil has been shown to be effective and well tolerated for malaria prophylaxis in residents of countries of endemicity and in nonimmune adult travelers, but data about traveling children are limited.
core +1 more source