Acute Hepatitis and Atovaquone/Proguanil [PDF]
Journal of Travel Medicine, 2006 A 31-year-old healthy man developed acute hepatitis after receiving atovaquone (250 mg) and proguanil (100 mg) for malaria prophylaxis daily for 25 days. Although atovaquone/proguanil is generally well-tolerated, this case highlights the hepatotoxic potential with considerable morbidity and should alert physicians to this harmful side effect.
Matthias, Grieshaber +2 more
openaire +2 more sources
Genetic and genomic approaches for the discovery of parasite genes involved in antimalarial drug resistance [PDF]
, 2013 The biggest threat to the war on malaria is the continued evolution of drug resistance by the parasite. Resistance to almost all currently available antimalarials now exists in Plasmodium falciparum which causes the most suffering among all human malaria
Mwangi, J.M., Ranford-Cartwright, L.C.
core +1 more source
Improved synchronous production of Plasmodium falciparum gametocytes in vitro.
, 2007 The sexual stages of the Plasmodium falciparum life cycle are attractive targets for vaccines and transmission blocking drugs. Difficulties in culturing and obtaining large amounts of sexual stage P.
Baker, David A +7 more
core +1 more source
Economics of Malaria Prevention in US Travelers to West Africa [PDF]
, 2013 Background. Pretravel health consultations help international travelers manage travel-related illness risks through education, vaccination, and medication. This study evaluated costs and benefits of that portion of the health consultation associated with
Adachi, Kenji +11 more
core +1 more source
Malaria Journal, 2006 Background Atovaquone is part of the antimalarial drug combination atovaquone-proguanil (Malarone®) and inhibits the cytochrome bc1 complex of the electron transport chain in Plasmodium spp.
Kremsner Peter G +4 more
doaj +1 more source
INNOVATIONS in Pharmacy, 2021 Purpose: This case report details the influence of media on patients and the responsibility of health care providers to educate their patients on proper use of medications, and to be aware of potential misadventures based on messages in popular media ...
Shaylee Anderson +2 more
doaj +1 more source
A longitudinal trial comparing chloroquine as monotherapy or in combination with artesunate, azithromycin or atovaquone-proguanil to treat malaria. [PDF]
PLoS ONE, 2012 The predominance of chloroquine-susceptible falciparum malaria in Malawi more than a decade after chloroquine's withdrawal permits contemplation of re-introducing chloroquine for targeted uses.
Miriam K Laufer +8 more
doaj +1 more source
An atypical presentation of malaria in a 19-year-old woman
IDCases, 2022 We describe an atypical presentation of malaria in a 19-year-old female who emigrated from Nigeria to the United States one year prior to presentation. Her primary complaint was fever and occipital headache radiating down to the neck.
Radhika Malhotra +3 more
doaj +1 more source
Safety, Immunogenicity, and Protective Efficacy of Intradermal Immunization with Aseptic, Purified, Cryopreserved Plasmodium falciparum Sporozoites in Volunteers Under Chloroquine Prophylaxis [PDF]
, 2016 Immunization of volunteers under chloroquine prophylaxis by bites of *Plasmodium falciparum* sporozoite (PfSPZ)–infected mosquitoes induces > 90% protection against controlled human malaria infection (CHMI).
Baestians, G.J.H. (Guido) +18 more
core +5 more sources
Progression of Malaria in the Human Body, Its Effects on the Liver and Its Various Aspects
Advanced Gut &Microbiome Research, Volume 2026, Issue 1, 2026.Malaria, an infectious disease caused by Plasmodium parasites, is a significant global health issue, particularly in tropical and subtropical regions. Understanding the development of malaria in the human body and its effects on vital organs like the liver is crucial for effective control and prevention.
Avishek Mandal +7 more
wiley +1 more source