Results 21 to 30 of about 3,499 (203)

Hair concentrations of anti-malarials in returned travellers-the HAIR study: Proof of principle analysis

Travel Medicine and Infectious Disease, 2023
Background: Hair analysis to identify substance use is an established methodology. This could also be a method to monitor adherence to antimalarial drugs.
Regula Steiner, Anne Kaulich, Daniel Müller, Patricia Schlagenhauf   +3 more
doaj   +1 more source

Treatment Failure and Post-Artesunate Delayed Haemolysis in a Returned Traveller From Uganda With Partially Drug-Resistant Severe Plasmodium falciparum Malaria. [PDF]

Med J Aust
ABSTRACT A man aged in his 40s, recently returned from Uganda, was hospitalised with Plasmodium falciparum malaria, with hyperparasitaemia of ~1.5 × 106 parasites/μL (26%). He received intravenous artesunate followed by artemether–lumefantrine. However, parasite clearance was delayed, and despite a negative blood film following treatment, the patient ...
Travis J, McCarthy K, Chapman P, Huang L, Tan A, Cheng Q, Barber BE.   +6 more
europepmc   +2 more sources

Malaria Screening and Treatment in Hematopoietic Cell Transplant Donors and Sickle Cell Disease Candidates/Recipients: A Case Series Using Malaria Polymerase Chain Reaction Testing and a Literature Review. [PDF]

Transpl Infect Dis
Malaria polymerase chain reaction (PCR) testing is more sensitive than conventional diagnostics. Routine PCR screening of at‐risk asymptomatic hematopoietic cell donors and transplant candidates may prevent unnecessary deferrals or treatment. In our experience, PCR negativity during screening or after treatment supports donor/candidate eligibility ...
Czech MM, Das S, Limerick E, Fitzhugh C, Hsieh M, Cuellar-Rodriguez J.   +5 more
europepmc   +2 more sources

Investigation of pre-clinical pharmacokinetic parameters of atovaquone nanosuspension prepared using a pH-based precipitation method and its pharmacodynamic properties in a novel artemisinin combination

Journal of Global Antimicrobial Resistance, 2020
Objectives: Recently, a growing resistance to antimalarial drugs such as chloroquine, sulfadoxine–pyrimethamine, artemisinin derivatives and mefloquine has been observed. The pharmacokinetic limitation of the current therapy and multi-drug resistance has
Harsha Kathpalia, Siddhesh Juvekar, Krishnapriya Mohanraj, Mrunal Apsingekar, Supriya Shidhaye   +4 more
doaj   +1 more source

Plasmodium knowlesi Infection in Traveler Returning to Canada from the Philippines, 2023

Emerging Infectious Diseases, 2023
A 55-year-old man sought treatment for an uncomplicated febrile illness after returning to Canada from the Philippines. A suspected diagnosis of Plasmodium knowlesi infection was confirmed by PCR, and treatment with atovaquone/proguanil brought ...
Calvin Ka-Fung Lo, Katherine Plewes, Sakuntla Sharma, Alicia Low, LingHui D. Su, Sara Belga, Ferdinand V. Salazar, Jan Hajek, Muhammad Morshed, Catherine A. Hogan   +9 more
doaj   +1 more source

Cost-effectiveness analysis of malaria chemoprophylaxis for travellers to West-Africa [PDF]

, 2010
Background: The importation of malaria to non-endemic countries remains a major cause of travel-related morbidity and a leading cause of travel-related hospitalizations. Currently they are three priority medications for malaria prophylaxis to West Africa:
Widmer, Lukas L, Blank, Patricia R, Van Herck, Koen, Hatz, Christoph, Schlagenhauf, Patricia   +4 more
core   +3 more sources

In vitro atovaquone/proguanil susceptibility and characterization of the cytochrome b gene of Plasmodium falciparum from different endemic regions of Thailand

Malaria Journal, 2008
Background The emergence of Plasmodium falciparum resistant to most currently used antimalarial drugs is the major problem in malaria control along the Thai-Myanmar and Thai-Cambodia borders.
Mungthin Mathirut, Tan-ariya Peerapan, Khositnithikul Rommanee   +2 more
doaj   +1 more source

Lord of the “rings”: A case of Plasmodium falciparum

IDCases, 2022
Plasmodium falciparum is the most common species to result in severe malaria infection. Examination of blood sample with thick and thin smear is the gold standard diagnostic test and repeat peripheral smear monitoring every 12–24 h should be performed ...
Marissa Li, Isin Y. Comba, Allison R. Eberly, Omar M. Abu Saleh   +3 more
doaj   +1 more source

Mutations in the Plasmodium falciparum cytochrome b gene are associated with delayed parasite recrudescence in malaria patients treated with atovaquone-proguanil

Malaria Journal, 2008
Background Fixed-dose combination antimalarial drugs have played an increasingly important role in the treatment and chemoprophylaxis of falciparum malaria since the worldwide failure of monotherapy with chloroquine.
Fivelman Quinton L, Burke Martina, Price Nicholas, Laundy Matt, Sutherland Colin J, Pasvol Geoffrey, Klein John L, Chiodini Peter L   +7 more
doaj   +1 more source

A review on characteristics and analytical methods of atovaquone – a potent antimalarial agent

Journal of Applied Pharmaceutical Research, 2020
Drugs used in the treatment of malaria that is caused by various plasmosium species i.e. P. falciparum, P. vivax are most irresistible disease throughout the world.
Sanyam Sharma, Rahul Sharma, Arti Devi, Shammy Jindal, Kamya Goyal   +4 more
doaj   +1 more source