Results 101 to 110 of about 105,612 (201)

Association of Genetic Variants With Rivaroxaban Pharmacokinetics and Pharmacodynamics and Hemorrhage Risk Factors in Patients With Venous Thromboembolism

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Rivaroxaban is a first‐line agent for venous thromboembolism prophylaxis and treatment. However, its pharmacokinetics, pharmacodynamics, and bleeding risk exhibit significant interindividual variability.
Hui Li, Xiaoshuang He, Yingyun Guan, Qiuya Lu, Jie Fang, Xiaolan Bian   +5 more
doaj   +1 more source

Bidirectional communication between nucleotide and substrate binding sites in a type IV multidrug ABC transporter

Nature Communications
ATP-binding cassette (ABC) transporters use ATP to transport substrates across membranes. In type IV ABC transporters, which include many multidrug resistance (MDR) pumps, communication between nucleotide-binding domains (NBDs) and transmembrane domains (
Victor Hugo Pérez Carrillo, Margot Di Cesare, Dania Rose-Sperling, Waqas Javed, Hannes Neuweiler, Julien Marcoux, Cédric Orelle, Jean-Michel Jault, Ute A. Hellmich   +8 more
doaj   +1 more source

Genome-wide identification of ATP-binding cassette transporter B subfamily, focusing on its structure, evolution and rearrangement in ciliates. [PDF]

Open Biol, 2023
Zhang X, Zhao Y, Zheng W, Nan B, Fu J, Qiao Y, Zufall RA, Gao F, Yan Y.   +8 more
europepmc   +1 more source

Drug resistance of hepatoma cells induced by ATP‑binding cassette transporter G2 by reducing intracellular drug concentration. [PDF]

Exp Ther Med, 2023
Li Y, Ding B, Liu J, Li X, He C, Wang J, Liu L.   +6 more
europepmc   +1 more source

The Impact of Polymorphisms in ATP-Binding Cassette Transporter Genes on Anthracycline-Induced Early Cardiotoxicity in Patients with Breast Cancer. [PDF]

J Cardiovasc Dev Dis, 2023
Muckiene G, Vaitiekus D, Zaliaduonyte D, Bartnykaite A, Plisiene J, Zabiela V, Juozaityte E, Jurkevicius R.   +7 more
europepmc   +1 more source

Structural Insights into Porphyrin Recognition by the Human ATP-Binding Cassette Transporter ABCB6. [PDF]

Mol Cells, 2022
Kim S, Lee SS, Park JG, Kim JW, Ju S, Choi SH, Kim S, Kim NJ, Hong S, Kang JY, Jin MS.   +10 more
europepmc   +1 more source

ATP-binding cassette transporter expression is widely dysregulated in frontotemporal dementia with TDP-43 inclusions. [PDF]

Front Mol Neurosci, 2022
Katzeff JS, Lok HC, Bhatia S, Fu Y, Halliday GM, Kim WS.   +5 more
europepmc   +1 more source

The role of ATP-binding cassette transporter genes expression in treatment failure cutaneous leishmaniasis. [PDF]

AMB Express, 2022
Boozhmehrani MJ, Eslami G, Khamesipour A, Jafari AA, Vakili M, Hosseini SS, Askari V.   +6 more
europepmc   +1 more source

A curated binary pattern multitarget dataset of focused ATP-binding cassette transporter inhibitors. [PDF]

Sci Data, 2022
Stefan SM, Jansson PJ, Pahnke J, Namasivayam V.   +3 more
europepmc   +1 more source

Role of nanostructured lipid carriers in the expression alterations of ATP-binding cassette transporter genes in fluconazole-resistant Candida glabrata. [PDF]

Bioimpacts, 2022
Moazeni M, Saeedi M, Kelidari H, Roohi B, Hedayati MT, Shokohi T, Nabili M, Asare-Addo K, Nokhodchi A.   +8 more
europepmc   +1 more source