Results 121 to 130 of about 59,687 (251)

Mosaic activation of the zebrafish hsp70l heat shock promoter: Implications for interpreting transgenes

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background The promoters and enhancers of heat shock genes, such as the 1.5‐kb promoter of the zebrafish hsp70l gene, are valuable tools for temporal activation of transgenes. It has been widely purported that heat shock treatments result in ubiquitous expression of hsp70l‐driven transgenes.
Jong‐Su Park, Xiangyun Wei
wiley   +1 more source

Climatic niche divergence and high‐elevation adaptation promoted rapid diversification of Pimoa spiders in Pan‐Himalaya

open access: yesEcography, EarlyView.
The Pan‐Himalayan region harbors exceptional biodiversity, yet the origins and underlying mechanisms driving this remarkable diversity remain poorly understood, especially among species‐rich invertebrates. Pimoa spiders exhibit an intercontinental disjunct distribution across three major mountain regions: the Rockies, the Alps, and the Pan‐Himalaya ...
Xiaoqing Zhang   +9 more
wiley   +1 more source

The gut microbiome and drug‐resistant epilepsy: Microbiome–antiseizure medication interactions and implications for pharmacoresistance

open access: yesEpilepsia Open, EarlyView.
Abstract Drug‐resistant epilepsy (DRE) affects approximately one‐third of patients with epilepsy and represents a major unmet clinical need. While traditional hypotheses of pharmacoresistance have focused on alterations in drug targets, efflux transporter overexpression, and intrinsic disease severity, the gut microbiome has recently emerged as a ...
Khaled Zammar   +4 more
wiley   +1 more source

A Plasmodium falciparum ATP-binding cassette transporter is essential for liver stage entry into schizogony. [PDF]

open access: yesiScience, 2022
Goswami D   +10 more
europepmc   +1 more source

Inconsistent Transcriptomic Responses to Hexabromocyclododecane in Japanese Quail: A Comparative Analysis of Results From Four Different Study Designs

open access: yesEnvironmental Toxicology and Chemistry, EarlyView.
Abstract Efforts to use transcriptomics for toxicity testing have classically relied on the assumption that chemicals consistently produce characteristic transcriptomic signatures that are reflective of their mechanism of action. However, the degree to which transcriptomic responses are conserved across different test methodologies has seldom been ...
Paul Béziers   +10 more
wiley   +1 more source

Home - About - Disclaimer - Privacy