Results 151 to 160 of about 105,612 (201)

ATP-Binding Cassette Transporters in Bacteria

Annual Review of Biochemistry, 2004
▪ Abstract  ATP-binding cassette (ABC) transporters couple ATP hydrolysis to the uptake and efflux of solutes across the cell membrane in bacteria and eukaryotic cells. In bacteria, these transporters are important virulence factors because they play roles in nutrient uptake and in secretion of toxins and antimicrobial agents. In humans, many diseases,
Amy L, Davidson, Jue, Chen
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ATP‐binding cassette transporters in liver

BioFactors, 2013
AbstractThe human ATP‐binding cassette (ABC) superfamily consists of 48 members with 14 of them identified in normal human liver at the protein level. Most of the ABC members act as ATP dependent efflux transport systems. In the liver, ABC transporters are involved in diverse physiological processes including export of cholesterol, bile salts, and ...
Katrin, Wlcek, Bruno, Stieger
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Plant ATP-Binding Cassette Transporters

Annual Review of Plant Biology, 2007
The ATP-binding cassette (ABC) protein superfamily is one of the largest known, with over 120 members in both Arabidopsis thaliana and rice (Oryza sativa). Most, but not all, ABC proteins are modularly organized membrane proteins (“ABC transporters”) that mediate MgATP-energized transmembrane transport and/or regulate other transporters.
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ATP-binding cassette transporters and neurodegenerative diseases

Essays in Biochemistry, 2021
Abstract ATP-binding cassette (ABC) transporters are one of the largest groups of transporter families in humans. ABC transporters mediate the translocation of a diverse range of substrates across cellular membranes, including amino acids, nucleosides, lipids, sugars and xenobiotics.
Jared S. Katzeff, Woojin Scott Kim
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ATP-Binding Cassette Transporters in the Heart

Trends in Cardiovascular Medicine, 2006
Members of the ATP-binding cassette (ABC) protein superfamily are integral membrane proteins involved in energy-dependent transport of a wide variety of substrates across biologic membranes. ATP-binding cassette transporters serve as functional barriers against the entry of xenobiotics, for example, in the intestine or at the blood-brain barrier, or ...
Thomas F, Solbach   +3 more
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ATP-binding cassette (ABC) transporters in atherosclerosis

Current Atherosclerosis Reports, 2002
Macrophages play a central role in the initiation and progression of atherosclerotic lesions. In the nascent lesion, macrophages transform into foam cells through the excessive accumulation of cholesteryl esters. Dysfunctional lipid homeostasis in macrophages and foam cells ultimately results in the breakdown of membrane integrity and cell death ...
Gerd, Schmitz, Wolfgang E, Kaminski
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