Results 1 to 10 of about 34,643 (109)
Twenty years of ATP-binding cassette (ABC) transporters [PDF]
Pflügers Archiv - European Journal of Physiology, 2018 ATP-binding cassette (ABC) transporters constitute a large superfamily of primary active transport systems, which play a diversity of physiological roles, and are found in all cells of all kingdoms [3]. The year 2006 marks the 20th anniversary of the identification of this superfamily of proteins in 1986 [4].
Higgins, Christopher, Stieger, Bruno
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ATP‐binding cassette transporters in nonmodel plants [PDF]
New Phytologist, 2021 SummaryKnowledge about plant ATP‐binding cassette (ABC) proteins is of great value for sustainable agriculture, economic yield, and the generation of high‐quality products, especially under unfavorable growth conditions. We have learned much about ABC proteins in model organisms, notably Arabidopsis thaliana; however, the importance of research ...
Joanna Banasiak, Michał Jasiński
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Thermodynamics of the ATPase Cycle of GlcV, the Nucleotide-Binding Domain of the Glucose ABC Transporter of Sulfolobus solfataricus [PDF]
, 2006 ATP-binding cassette transporters drive the transport of substrates across the membrane by the hydrolysis of ATP. They typically have a conserved domain structure with two membrane-spanning domains that form the transport channel and two cytosolic ...
Albers, Sonja-Verena, +5 more
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Peptides and ATP binding cassette peptide transporters [PDF]
Research in Microbiology, 2001 In this review our knowledge of ATP binding cassette (ABC) transporters specific for peptides is discussed. Besides serving a role in nutrition of the cell, the systems participate in various signaling processes that allow (micro)organisms to monitor the local environment. In bacteria, these include regulation of gene expression, competence development,
Detmers, F.J.M. +2 more
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The Human ATP-Binding Cassette (ABC) Transporter Superfamily [PDF]
Genome Research, 2001 The ATP-binding cassette (ABC) transporter superfamily comprises membrane proteins that efflux various substrates across extra- and intra-cellular membranes. Mutations in ABC genes cause 21 human disorders or phenotypes with Mendelian inheritance, including cystic fibrosis, adrenoleukodystrophy, retinal degeneration, cholesterol, and bile ...
Michael Dean +2 more
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ECF-Type ATP-Binding Cassette Transporters [PDF]
Annual Review of Biochemistry, 2019 Energy-coupling factor (ECF)–type ATP-binding cassette (ABC) transporters catalyze membrane transport of micronutrients in prokaryotes. Crystal structures and biochemical characterization have revealed that ECF transporters are mechanistically distinct from other ABC transport systems.
Weronika K. Stanek +2 more
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The impact of ATP-binding cassette transporters on metabolic diseases [PDF]
Nutrition & Metabolism, 2020 AbstractCurrently, many people worldwide suffer from metabolic diseases caused by heredity and external factors, such as diet. One of the symptoms of metabolic diseases is abnormal lipid metabolism. ATP binding cassette (ABC) transporters are one of the largest transport protein superfamilies that exist in nearly all living organisms and are mainly ...
Zixiang Ye, Yifei Lu, Tao Wu
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ATP-Binding Cassette Transporters, Atherosclerosis, and Inflammation [PDF]
Circulation Research, 2014 Although recent genome-wide association studies have called into question the causal relationship between high-density lipoprotein (HDL) cholesterol levels and cardiovascular disease, ongoing research in animals and cells has produced increasing evidence that cholesterol efflux pathways mediated by ATP-binding cassette (ABC) transporters and HDL ...
Nan Wang +5 more
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Conservation of structure and mechanism in primary and secondary transporters exemplified by SiaP, a sialic acid binding virulence factor from Haemophilus influenzae [PDF]
, 2006 Extracytoplasmic solute receptors (ESRs) are important components of solute uptake systems in bacteria, having been studied extensively as parts of ATP binding cassette transporters.
Kelly, D.J. +7 more
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ABC transporters: the power to change [PDF]
, 2009 ATP-binding cassette (ABC) transporters constitute a ubiquitous superfamily of integral membrane proteins that are responsible for the ATP-powered translocation of many substrates across membranes.
Johnson, Eric +2 more
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