Results 171 to 180 of about 156,745 (364)

Single-molecule visualization of ATP-induced dynamics of the subunit composition of an ECF transporter complex under turnover conditions

open access: yesNature Communications
Energy-Coupling Factor (ECF) transporters are ATP-binding cassette (ABC) transporters essential for uptake of vitamins and cofactors in prokaryotes. They have been linked to pathogen virulence and are potential targets for antimicrobials.
Solène N. Lefebvre   +3 more
doaj   +1 more source

Data-Driven Prediction of CRISPR-Based Transcription Regulation for Programmable Control of Metabolic Flux [PDF]

open access: yesarXiv, 2017
Multiplex and multi-directional control of metabolic pathways is crucial for metabolic engineering to improve product yield of fuels, chemicals, and pharmaceuticals. To achieve this goal, artificial transcriptional regulators such as CRISPR-based transcription regulators have been developed to specifically activate or repress genes of interest.
arxiv  

Photoaffinity labeling coupled to MS to identify peptide biological partners: Secondary reactions, for better or for worse?

open access: yesMass Spectrometry Reviews, EarlyView.
Abstract Affinity photolabeling is a smart method to study noncovalent and transient interactions and provide a submolecular picture of the contacts between interacting partners. In this review, we will focus on the identification of peptide partners using photoaffinity labeling coupled to mass spectrometry in different contexts such as in vitro with a
Astrid Walrant, Emmanuelle Sachon
wiley   +1 more source

Inhibitory Effects of Salinispora-derived Metabolites Against Multidrug Resistance: An In-silico Study

open access: yesPharmaceutical and Biomedical Research, 2020
Background: Multi drug resistance (MDR) is known to defeat most chemotherapies as one of the main anticancer strategies. The role of overexpression or overactivation of ATP-binding cassette (ABC) transporters, especially P-glycoprotein (P-gp), in the ...
Morteza Ghandadi
doaj  

Cloning, characterization and tissue distribution of the rat ATP-binding cassette (ABC) transporter ABC2/ABCA2 [PDF]

open access: green, 2000
Lixia Zhao   +8 more
openalex   +1 more source

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