Pharmaceutical and Biomedical Research, 2020 Background: Multi drug resistance (MDR) is known to defeat most chemotherapies as one of the main anticancer strategies. The role of overexpression or overactivation of ATP-binding cassette (ABC) transporters, especially P-glycoprotein (P-gp), in the ...
Morteza Ghandadi
doaj
Beauvericin potentiates the activity of pesticides by neutralizing the ATP-binding cassette transporters in arthropods. [PDF]
Sci Rep, 2021 Al Khoury C, Nemer N, Nemer G.
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The Methods to Overcome ATP-binding Cassette Transporters-mediated Multi-drug Resistance
مجله دانشکده پزشکی اصفهان, 2013 Background: Multi-drug resistance (MDR) is a prevalent phenomenon occurred in tumor cells in response to chemotherapy. The main cause of MDR is the efflux of drugs by ATP-binding Cassette (ABC) transporters.
Mansoureh Entezar-e-Ghaem +2 more
doaj
Identification and Validation of Prognostic Related Hallmark ATP-Binding Cassette Transporters Associated With Immune Cell Infiltration Patterns in Thyroid Carcinoma. [PDF]
Front Oncol, 2022 Wang L, Sun X, He J, Liu Z.
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, 2009 Human ATP-binding cassette transporters (ABC transporter) belong to an extremely important superfamily of membrane transporters. They use energy from ATP hydrolysis to transport a wide variety of substrates across the cellular membrane.
Mo, Wei, Zhang, Jian-Ting
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Interdisciplinary Medicine, EarlyView.This review explores how Fusobacterium nucleatum extracellular vesicles drive local oral diseases and distal pathologies via sophisticated cross‐compartment cross talk. It highlights the transformative potential of these “tiny carriers” as next‐generation molecular intermediaries for advanced health monitoring and innovative bio‐interventions by ...
Rongyang Ma +6 more
wiley +1 more source
Growth hormone receptor antagonism downregulates ATP-binding cassette transporters contributing to improved drug efficacy against melanoma and hepatocarcinoma in vivo. [PDF]
Front Oncol, 2022 Basu R +22 more
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Pharmacogenetics of ATP-binding cassette transporters in cancer and chemotherapy
, 2003 The ATP-binding cassette (ABC) transporters belong to the largest known transporter gene family and translocate a variety of substrates including chemotherapy agents.
Tirona, Rommel G +2 more
core
Interdisciplinary Medicine, EarlyView.Hydrogel‐based drug delivery systems offer a promising approach for treating intracerebral hemorrhage (ICH) by overcoming blood‐brain barrier limitations, enabling precise, sustained release of neuroprotective and anti‐inflammatory agents. These systems enhance treatment efficacy, but challenges remain in biosafety, drug penetration, and scalability ...
Haojun Shi +18 more
wiley +1 more source
New and Emerging Research on Solute Carrier and ATP Binding Cassette Transporters in Drug Discovery and Development: Outlook From the International Transporter Consortium. [PDF]
Clin Pharmacol Ther, 2022 Giacomini KM +9 more
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