Results 181 to 190 of about 84,320 (339)

Cellular Export of Drugs and Signaling Molecules by the ATP-binding Cassette Transporters MRP4 (ABCC4) and MRP5 (ABCC5)

, 2005
Christoph A. Ritter, Gabriele Jedlitschky, Henriette E. Meyer zu Schwabedissen, Markus Grube, Kathleen Köck, Heyo K. Kroemer   +5 more
openalex   +1 more source

Supplementary Figure Legends 1-3 from Apatinib (YN968D1) Reverses Multidrug Resistance by Inhibiting the Efflux Function of Multiple ATP-Binding Cassette Transporters [PDF]

, 2023
Yanjun Mi, Yong-ju Liang, Hongbing Huang, Hongyun Zhao, Chung‐Pu Wu, Fang Wang, Li-yang Tao, Chuan-zhao Zhang, Chun‐Ling Dai, Amit K. Tiwari, Xiaoxu Ma, Kenneth K.W. To, Suresh V. Ambudkar, Zhe‐Sheng Chen, Liwu Fu   +14 more
openalex   +1 more source

Mixed‐mode membrane chromatography: mechanistic‐modeling‐based optimization and scale‐up of antibody charge variant separation using a novel membrane adsorber

Journal of Chemical Technology &Biotechnology, EarlyView.
Abstract BACKGROUND Efficient manufacturing of complex biopharmaceuticals increasingly relies on innovative downstream processing strategies. Membrane chromatography offers a promising alternative to resin‐based systems by enabling high‐throughput separations at elevated flow rates. Typically used in flow‐through mode, its industrial applications range
Jan Hedrich, Rita Steigmiller, Viktor Simaev, Romas Skudas, Michael Schulte, Mathias Hafner, Christian Frech   +6 more
wiley   +1 more source

Role of ATP-binding cassette transporters, apoptosis, and long non-coding RNAs in gastric cancer multidrug resistance

, 2017
Zhaoying Fu
openalex   +1 more source

CCAAT/Enhancer-binding protein delta mediates glioma stem-like cell enrichment and ATP-binding cassette transporter ABCA1 activation for temozolomide resistance in glioblastoma [PDF]

, 2021
Shao‐Ming Wang, Wen-chi Lin, Hong-Yi Lin, Yen‐Lin Chen, Chiung‐Yuan Ko, Ju-Ming Wang   +5 more
openalex   +1 more source

The roles of the human ATP-binding cassette transporters P-glycoprotein and ABCG2 in multidrug resistance in cancer and at endogenous sites: future opportunities for structure-based drug design of inhibitors. [PDF]

Cancer Drug Resist, 2021
Goebel J, Chmielewski J, Hrycyna CA.
europepmc   +1 more source

Investigating the Role of ATP-Binding Cassette Transporters in Drosophila melanogaster Testis Stem Cells

, 2021
Israel J Wipf
openalex   +1 more source

Molecular Insights Into Canine Hepatocellular Carcinoma: A Cross‐Species Transcriptomic Comparison With Human HCC

Molecular Carcinogenesis, EarlyView.
ABSTRACT Canine hepatocellular carcinoma (HCC) requires further molecular characterization to identify diagnostic and therapeutic targets, and to establish whether dogs with this condition can model the human disease. Accordingly, we aimed to identify differentially expressed genes (DEGs) in canine HCC and evaluate cross‐species transcriptomic ...
Mohammad Arif, MD Nazmul Hasan, Nobuhiro Nozaki, Yutaro Ide, Yoshiyuki Akiyama, Shaohsu Wang, Most Shumi Akhter Shathi, Osamu Yamato, Naoki Miura   +8 more
wiley   +1 more source

ATP-binding cassette transporters restrict drug delivery and efficacy against brain tumors even when blood-brain barrier integrity is lost. [PDF]

Cell Rep Med, 2021
de Gooijer MC, Kemper EM, Buil LCM, Çitirikkaya CH, Buckle T, Beijnen JH, van Tellingen O.   +6 more
europepmc   +1 more source

The ketogenic diet alters microbiome‐metabolome profiles to improve West syndrome therapy

Pediatric Investigation, EarlyView.
The ketogenic diet alleviates West syndrome by reshaping gut microbiota (increasing Bacteroides, Parabacteroides, and reducing Escherichia and Bifidobacterium), and modulating metabolites—including anticonvulsant lipids (e.g., capric acid), suppressed harmful lipids (e.g., 2‐methylbutyroylcarnitine), and amino acids and analogs (e.g., 3‐sulfinoalanine)—
Gan Xie, Qian Zhou, Jianxiang Liao, Yuejie Zheng, Wenjian Wang, Kunling Shen   +5 more
wiley   +1 more source