Results 181 to 190 of about 156,745 (364)

Mediterranean Diet Modulates Gene Expression of Cholesterol Efflux Receptors in High‐Risk Cardiovascular Patients

Molecular Nutrition &Food Research, EarlyView.
The graphical abstract (GA) displays the study of two randomized trials studying the molecular mechanisms of cholesterol efflux‐related genes analyzed via transcriptomics after two Mediterranean diet interventions. Cholesterol efflux molecules include ATP‐binding cassette transporters ABCA1 and ABCG1 in cholesterol transport to HDL. It also depicts the
Javier Hernando‐Redondo, Álvaro Hernáez, Albert Sanllorente, Xavier Pintó, Ramón Estruch, Jordi Salas‐Salvadó, Dolores Corella, Fernando Arós, Miguel Ángel Martínez‐González, Isaac Subirana, Daniel Muñoz‐Aguayo, Mireia Malcampo, Lluis Serra‐Majem, Dora Romaguera, Jose Lapetra, Emilio Ros, Francisco Tinahones, Rosa Maria Lamuela‐Raventós, Enrique Gómez‐Gracia, Montserrat Fitó, Olga Castañer   +20 more
wiley   +1 more source

The Methods to Overcome ATP-binding Cassette Transporters-mediated Multi-drug Resistance

مجله دانشکده پزشکی اصفهان, 2013
Background: Multi-drug resistance (MDR) is a prevalent phenomenon occurred in tumor cells in response to chemotherapy. The main cause of MDR is the efflux of drugs by ATP-binding Cassette (ABC) transporters.
Mansoureh Entezar-e-Ghaem, Soheila Rahgozar, Ali Reza Moafi   +2 more
doaj  

Beauvericin potentiates the activity of pesticides by neutralizing the ATP-binding cassette transporters in arthropods. [PDF]

Sci Rep, 2021
Al Khoury C, Nemer N, Nemer G.
europepmc   +1 more source

Fast Antibiotic resistance-Based gene editing of mammalian cells with CRISPR-Cas9 (FAB-CRISPR) [PDF]

arXiv
Protein tagging with CRISPR-Cas9 enables the investigation of protein function in its native environment but is limited by low homology-directed repair (HDR) efficiency causing low knock-in rates. We present a detailed pipeline using HDR donor plasmids containing antibiotic resistance cassettes for rapid selection of gene-edited cells.
arxiv  

The homodimeric ATP-binding cassette transporter LmrA mediates multidrug transport by an alternating two-site (two-cylinder engine) mechanism [PDF]

, 2000
Hendrik W. van Veen
openalex   +1 more source

PGC‐1α Activation by Polyphenols: A Pathway to Thermogenesis

Molecular Nutrition &Food Research, EarlyView.
Polyphenols, derived from dietary sources such as berries, undergo digestion and interact with gut microbiota, leading to their metabolization in the liver. This process influences bile acid composition, which in turn activates PGC1α, a key regulator of mitochondrial biogenesis and thermogenesis.
Nicholas Vannuchi, Luciana Pisani
wiley   +1 more source

Growth hormone receptor antagonism downregulates ATP-binding cassette transporters contributing to improved drug efficacy against melanoma and hepatocarcinoma in vivo. [PDF]

Front Oncol, 2022
Basu R, Qian Y, Mathes S, Terry J, Arnett N, Riddell T, Stevens A, Funk K, Bell S, Bokal Z, Batten C, Smith C, Mendez-Gibson I, Duran-Ortiz S, Lach G, Mora-Criollo PA, Kulkarni P, Davis E, Teaford E, Berryman DE, List EO, Neggers S, Kopchick JJ.   +22 more
europepmc   +1 more source

Early Commissioning Results of Slit Mask Integral Field Units on the Southern African Large Telescope [PDF]

arXiv
Three fibre feed integral field units (IFUs), called Slit Mask IFUs (SMI), are being developed in the SAAO fibre-lab for the Robert Stobie Spectrograph (RSS). The smaller, 200 micron fibre IFU (SMI-200) has 309 x 0.9 arcsec diameter spatial elements covering an elongated hexagonal footprint of 18 $\times$ 23 arcsec is now being commissioned. The larger,
arxiv  

Resveratrol Prevents Weight Gain, Counteracts Visceral Adipose Tissue Dysfunction, and Improves Hypothalamic Leptin Sensitivity in Diet‐Induced Obese Rats

Molecular Nutrition &Food Research, EarlyView.
Resveratrol improves hypothalamic leptin sensitivity and prevents body weight gain in obese animals, while mitigating adipocyte hypertrophy and promoting adipocyte hyperplasia in the retroperitoneal fat depot. ABSTRACT In obesity, increased adipocyte size is associated with metabolic complications, while elevated adipocyte numbers are considered a ...
Maria Ibars‐Serra, Aïda Pascual‐Serrano, Andrea Ardid‐Ruiz, Núria Doladé, Sonia Aguilar‐González, Julieta Cirasino, Begoña Muguerza, Manuel Suárez, Jaap Keijer, Anna Arola‐Arnal, Gerard Aragonès   +10 more
wiley   +1 more source

Characterization of a Sinorhizobium meliloti ATP-Binding Cassette Histidine Transporter Also Involved in Betaine and Proline Uptake [PDF]

, 2000
Éric Boncompagni, Laurence Dupont, Tâm Mignot, Magne Østerås, Annie Lambert, Marie-Christine Poggi, Daniel Le Rudulier   +6 more
openalex   +1 more source