Results 211 to 220 of about 84,320 (339)

Multidrug efflux pumps: The structures of prokaryotic ATP‐binding cassette transporter efflux pumps and implications for our understanding of eukaryotic P‐glycoproteins and homologues [PDF]

, 2009
Ian D. Kerr, Peter M. Jones, Anthony M. George   +2 more
openalex   +1 more source

Nanomedicine Meets Immunotherapy: Transforming Chimeric Antigen Receptor T Cell Treatment for Solid Tumors

Small Science, EarlyView.
This review highlights recent advances in nanomedicine that enhance chimeric antigen receptor (CAR) T cell therapy against solid tumors. It discusses key barriers to CAR T cell efficacy and outlines nanotechnology‐based strategies to improve tumor targeting, remodel the immunosuppressive microenvironment, and integrate nanomaterials into CAR T cell ...
Stephen O’Rourke, Nuo Xu, Hongjun Wang, Hexin Chen   +3 more
wiley   +1 more source

Brain Pericytes and Wnt/β‐Catenin Signaling Induce Functional Blood–Brain Barrier Phenotype in Human iPSC‐Derived Model

Small Methods, EarlyView.
This study shows that human iPSC‐derived endothelial cells acquire a functional blood–brain barrier phenotype when co‐cultured with brain pericytes and stimulated with CHIR‐99021, a Wnt/β‐catenin activator. This model recapitulates key barrier properties, inflammatory responses, and transcriptomic features of the native human BBB, offering new ...
Henrique Nogueira Pinto, Nine R. Kok, Philipp C. Hauger, Manon Karsten‐van Diepen, Michael de Kok, Nanne J. Paauw, Susanne M. A. van der Pol, Joline P. Nugteren‐Boogaard, Peter L. Hordijk, Stephanie D. Beekhuis‐Hoekstra, Susan Gibbs, Nienke M. de Wit, Helga E. de Vries   +12 more
wiley   +1 more source

Multidrug ATP‐binding cassette transporters are essential for hepatic development of Plasmodium sporozoites [PDF]

, 2015
Sanna R. Rijpma, Maarten van der Velden, María González‐Pons, Takeshi Annoura, Ben C. L. van Schaijk, Geert‐Jan van Gemert, Jeroen J. M. W. van den Heuvel, Jai Ramesar, Séverine Chevalley‐Maurel, Ivo Ploemen, Shahid M. Khan, Jean‐François Franetich, Dominique Mazier, Johannes H. W. de Wilt, Adelfa E. Serrano, Frans G. M. Rüssel, Chris J. Janse, Robert W. Sauerwein, Jan J. Koenderink, Blandine Franke‐Fayard   +19 more
openalex   +1 more source

Disruption oflolCDE, Encoding an ATP-Binding Cassette Transporter, Is Lethal forEscherichia coliand Prevents Release of Lipoproteins from the Inner Membrane

, 2002
Shin‐ichiro Narita, Kimie Tanaka, Shin‐ichi Matsuyama, Hajime Tokuda   +3 more
openalex   +2 more sources

Hydrogen Activates ATP-Binding Cassette Transporter A1-Dependent Efflux Ex Vivo and Improves High-Density Lipoprotein Function in Patients With Hypercholesterolemia: A Double-Blinded, Randomized, and Placebo-Controlled Trial [PDF]

, 2015
Guohua Song, Quanqiang Lin, Hui Zhao, Mei‐Yuan Liu, Fenglong Ye, Yujuan Sun, Yang Yu, Shoudong Guo, Peng Jiao, Yun Wu, Guoyong Ding, Qiang Xiao, Shucun Qin   +12 more
openalex   +1 more source

Exploring the Impact of Polystyrene Microplastic Beads on Male Gonads of the Marine Mussel, Mytilus galloprovincialis

Environmental Toxicology, EarlyView.
ABSTRACT Plastic, with its remarkable versatility and numerous applications, has greatly benefited humanity. However, its extreme resistance to natural degradation means it persists in the environment for long periods, causing global environmental problems.
Teresa Chianese, Mariachiara Galati, Tiziana Cappello, Maria Maisano, Gennaro Lettieri, Carmela Marinaro, Marina Piscopo, Gianluca Fasciolo, Carlos Gravato, Gaetana Napolitano, Giulia Paolella, Annamaria Locascio, Rosaria Scudiero, Luigi Rosati   +13 more
wiley   +1 more source

The Effect of Nanosystems on ATP-Binding Cassette Transporters: Understanding the Influence of Nanosystems on Multidrug Resistance Protein-1 and P-glycoprotein. [PDF]

Int J Mol Sci, 2020
Mello FVC, de Moraes GN, Maia RC, Kyeremateng J, Iram SH, Santos-Oliveira R.   +5 more
europepmc   +1 more source

Intracellular cholesterol transporters and modulation of hepatic lipid metabolism: implications for diabetic dyslipidaemia and steatosis [PDF]

, 2014
Caridis, Anna-Maria, Dolan, Sharron, Graham, Annette, Soffientini, Ugo   +3 more
core   +1 more source

369 – Targeted Deletion of the Atp-Binding Cassette Sterol Transporter G8 (ABCG8) Gene Enhances Susceptibility to Nonalcoholic Fatty Liver Disease (NAFLD) and Nonalcoholic Steatohepatitis (NASH) by Reducing Hepatic Cholesterol (CH) Secretion and Increasing Intestinal CH Absorption in Mice

, 2019
Helen H. Wang, David Q. Wang
openalex   +1 more source