Urinary ATP as an indicator of infection and inflammation of the urinary tract in patients with lower urinary tract symptoms [PDF]
BACKGROUND: Adenosine-5'-triphosphate (ATP) is a neurotransmitter and inflammatory cytokine implicated in the pathophysiology of lower urinary tract disease. ATP additionally reflects microbial biomass thus has potential as a surrogate marker of urinary
A Kupelian+39 more
core +2 more sources
Fondová schémata jako možná řešení finanční udržitelnosti dánského penzijního systému
The financial sustainability of pension systems is one of the crucial topics in the context of population aging. The issue of financial sustainability is primarily associated with public unfunded pension schemes, where there is an increase in future ...
Jan Pokorný, Pavlína Hejduková
doaj +1 more source
Dynamics of Neuronal and Astrocytic Energy Molecules in Epilepsy
The dynamics of energy molecules in the mouse brain during metabolic challenges induced by epileptic seizures were studied using transgenic mice with FRET‐based pyruvate or ATP sensors selectively expressed in astrocytes or neurons, respectively. In response to epileptic neuronal hyperactivity, astrocytic cytosolic pyruvate levels increased, while ...
Kota Furukawa+7 more
wiley +1 more source
Energy requirements for unfolding and membrane translocation of precursor proteins during import into mitochondria [PDF]
ATP is involved in conferring transport competence to numerous mitochondrial precursor proteins in the cytosol. Unfolded precursor proteins were found not to require ATP for import into mitochondria, suggesting a role of ATP in the unfolding of ...
Guiard, Bernard+5 more
core
Principal factors that determine the extension of detection range in molecular beacon aptamer/conjugated polyelectrolyte bioassays. [PDF]
A strategy to extend the detection range of weakly-binding targets is reported that takes advantage of fluorescence resonance energy transfer (FRET)-based bioassays based on molecular beacon aptamers (MBAs) and cationic conjugated polyelectrolytes (CPEs).
Bazan, Guillermo C+5 more
core +1 more source
Partitioning of ATP generation between glycolysis and oxidative phosphorylation is central to cellular bioenergetics but cumbersome to measure. We describe here how rates of ATP generation by each pathway can be calculated from simultaneous measurements ...
S. Mookerjee+3 more
semanticscholar +1 more source
Once a saint, now a sinner: An appropriate or inappropriate shock?
Critical analysis of electrograms of any therapy delivery event is paramount to identify the etiology, specificity, and sensitivity of the programmed algorithms to differentiate supraventricular versus ventricular tachycardia, its effectiveness, and potential interventions to prevent recurrence.
Sudipta Mondal+3 more
wiley +1 more source
ATP-consuming and ATP-generating Enzymes Secreted by Pancreas [PDF]
Pancreatic acini release ATP in response to various stimuli, including cholecystokinin octapeptide (CCK-8), as we show in the present study. There were indications that pancreatic juice also contains enzymes that could hydrolyze ATP during its passage through the ductal system. The aim of this study was to determine which ATP-degrading and possibly ATP-
Yegutkin, Gennady G+3 more
openaire +3 more sources
ATP mediates both activation and inhibition of K(ATP) channel activity via cAMP-dependent protein kinase in insulin-secreting cell lines. [PDF]
The single-channel recording technique was employed to investigate the mechanism conferring ATP sensitivity to a metabolite-sensitive K channel in insulin-secreting cells.
Ciani, S, Eddlestone, GT, Ribalet, B
core
Time‐restricted feeding (TRF) impacts skeletal muscle physiology and metabolism through microbiome modulation. In Drosophila models, TRF altered microbiota composition, increasing beneficial Acetobacter pasteurianus (AP) and reducing harmful Staphylococcus aureus (SA).
Christopher Livelo+4 more
wiley +1 more source