Results 81 to 90 of about 1,728,775 (305)

The motor of the ATP synthase

open access: yesBiochimica et Biophysica Acta (BBA) - Bioenergetics, 1998
A model is presented in which ion translocation through the F0 part of the ATP synthase drives the rotation of the ring of c subunits (rotor) versus the a subunit (stator). The coupling ion binding sites on the rotor are accessible from the cytoplasm of a bacterial cell except for the c subunit at the interface to the stator.
Peter Dimroth   +2 more
openaire   +3 more sources

Extracellular ATP drives systemic inflammation, tissue damage and mortality [PDF]

open access: yes, 2014
Systemic inflammatory response syndromes (SIRS) may be caused by both infectious and sterile insults, such as trauma, ischemia-reperfusion or burns. They are characterized by early excessive inflammatory cytokine production and the endogenous release of ...
Brouckaert, Peter   +4 more
core   +1 more source

Changes in contractile characteristics of rat skeletal muscles associated with P2-receptor activation after spinal cord transection [PDF]

open access: yesАнналы клинической и экспериментальной неврологии
Introduction. Traumatic spinal cord and peripheral-nerve injury is associated with release of proinflammatory cytokines and chemokines, which may stimulate neuronal activity.
Adel E. Khairullin   +6 more
doaj   +1 more source

Persister formation in Staphylococcus aureus is associated with ATP depletion

open access: yesNature Microbiology, 2016
Persisters are dormant phenotypic variants of bacterial cells that are tolerant to killing by antibiotics1. Persisters are associated with chronic infections and antibiotic treatment failure1–3.
Brian P. Conlon   +9 more
semanticscholar   +1 more source

ATP‐Regulated Formation of Transient Peptide Amphiphiles Superstructures

open access: yesSmall, Volume 21, Issue 13, April 2, 2025.
This work reports the formation of peptide amphiphile bundled superstructures through ATP‐driven charge screening. The transient nature of these hierarchical self‐assembled nanostructures is regulated by enzymatic ATP hydrolysis. Using this approach also controls the chemical reactivity and catalytic function of peptide nanostructures.
David Cappelletti   +3 more
wiley   +1 more source

Cryo-EM structure of the mammalian ATP synthase tetramer bound with inhibitory protein IF1

open access: yesScience, 2019
ATP production under lockdown Cellular processes must respond to change, often by speeding up, slowing down, or stopping altogether. Adenosine triphosphate (ATP) synthases use a transmembrane proton gradient to produce ATP, but this reaction can go in ...
Jinke Gu   +8 more
semanticscholar   +1 more source

Enzymatic Reaction Network‐Driven Polymerization‐Induced Transient Coacervation

open access: yesAngewandte Chemie International Edition, Volume 64, Issue 11, March 10, 2025.
An enzymatic reaction network (ERN) for polymerization‐induced transient coacervation (ERN‐PIC), with complete control over the system: polymerization, coacervation, dissolution and selective cargo uptake. Abstract A living cell has a highly complex microenvironment whereas numerous enzyme‐driven processes are active at once.
Surbhi Sharma   +3 more
wiley   +1 more source

ATP signalling in epilepsy

open access: yesPurinergic Signalling, 2008
This paper focuses on a role for ATP neurotransmission and gliotransmission in the pathophysiology of epileptic seizures. ATP along with gap junctions propagates the glial calcium wave, which is an extraneuronal signalling pathway in the central nervous system.
Kumaria, A, Tolias, CM, Burnstock, G
openaire   +4 more sources

Intracellular Adenosine Triphosphate (ATP) Concentration: A Switch in the Decision Between Apoptosis and Necrosis

open access: yesJournal of Experimental Medicine, 1997
Apoptosis and necrosis are considered conceptually and morphologically distinct forms of cell death. Here, we report that demise of human T cells caused by two classic apoptotic triggers (staurosporin and CD95 stimulation) changed from apoptosis to ...
M. Leist   +4 more
semanticscholar   +1 more source

TRPV4 stimulates colonic afferents through mucosal release of ATP and glutamate

open access: yesBritish Journal of Pharmacology, Volume 182, Issue 6, Page 1324-1340, March 2025.
Background and Purpose Abdominal pain is a leading cause of morbidity for people living with gastrointestinal disease. Whereas the transient receptor potential vanilloid 4 (TRPV4) ion channel has been implicated in the pathogenesis of abdominal pain, the relative paucity of TRPV4 expression in colon‐projecting sensory neurons suggests that non‐neuronal
Michelle Y. Meng   +14 more
wiley   +1 more source

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