Results 71 to 80 of about 18,860 (162)

Maternal nutrition as a key determinant of placental and developing blood–brain barrier xenobiotic protective functions

The Journal of Physiology, EarlyView.
Abstract figure legend Suboptimal maternal nutrition alters placental and developing blood–brain barrier (BBB) protective function and is associated with increased fetal brain vulnerability. In the placenta, nutritional adversity may reduce the exchange surface area and promote meta‐inflammation, compromising barrier efficiency in a model‐ and context ...
Kristin L. Connor, Nycolle I. S. Souza, Bruno G. Anjos, Stephen G. Matthews, Enrrico Bloise   +4 more
wiley   +1 more source

Vascular smooth muscle cell mechanotransduction: Pathways, phenotypes and emerging technologies

The Journal of Physiology, EarlyView.
Abstract figure legend Vascular smooth muscle cells are exposed to mechanical stimuli from the blood flow and the extracellular matrix. The cells sense the signals from cyclic stretch, shear stress, hydrostatic pressure and matrix stiffness through specialized mechanosensors, such as mechanosensitive ion channels or cell surface receptors including ...
Nivethitha Kota Lakshminaraasimulu, Rachel E. A. Smyth, Aishwarya Prakash, Thomas Iskratsch   +3 more
wiley   +1 more source

Oxysterols in Cancer: From Biosynthesis and Pathophysiology to Targeted Therapeutics

MedComm – Oncology, Volume 5, Issue 3, September 2026.
Mechanisms by which oxysterol targeting may enhance immunotherapy efficacy. This figure illustrates potential metabolic interventions that may improve antitumor immunity by modulating oxysterol related pathways. CH25H modulation may reduce 25‐HC accumulation, promote the conversion of cold tumors into hot tumors, and increase T cell infiltration and PD‐
Haili Shang, Yongsheng Li
wiley   +1 more source

Inducing Antigen‐Specific and Functional Immune Responses in Mice Toward Bovine Herpesvirus 1 and Bovine Respiratory Syncytial Virus by Chimeric Peptides Delivered by Bovine Herpesvirus 4‐Based Vector

Immunology, Volume 179, Issue 1, Page 54-71, September 2026.
Bovine Alphaherpesvirus 1 (BoHV‐1) and Bovine respiratory syncytial virus (BRSV) are major drivers of respiratory disease in cattle. (A) To target both pathogens, two chimeric antigens—membrane‐linked and secreted—combining BoHV‐1 glycoprotein D and BRSV fusion glycoprotein were designed and expressed using recombinant BoHV‐4‐based vectors.
Antonino Di Lorenzo, Sergio Minesso, Chiara Cossu, Valentina Franceschi, Elisabetta Bolli, Vittorio Madia, Laura Conti, Gaetano Donofrio   +7 more
wiley   +1 more source

Identification of TAP2 as a novel immune target in human cancers: insights from integrated bioinformatics and experimental approaches

European Journal of Medical Research
Background Transporter 2, ATP binding cassette (ABC) subfamily B member (TAP2), encodes a protein within the ABC transporter superfamily. TAP2 plays a role in the progression of cancers, such as cervical, breast, and lung cancers.
Lufei Yang, Jiawei Gui, Yilei Sheng, Junzhe Liu, Chong Wang, Zhansheng Fang, Le Huang, Zewei Tu, Xingen Zhu, Kai Huang   +9 more
doaj   +1 more source

Dual Functions of Dietary Rubber Seed Oil Supplementation: Enriching N‐3 Polyunsaturated Fatty Acids and Enhancing Antioxidant Capacity in Pekin Ducks

Animal Research and One Health, Volume 4, Issue 3, Page 247-260, August 2026.
Dietary RSO supplementation improved growth performance, simultaneously enriched n‐3 polyunsaturated fatty acids (n‐3 PUFA), and enhanced antioxidant capacity in Pekin ducks, which suggested that RSO has the potential to be a novel n‐3 PUFA source and an antioxidant for Pekin ducks to generate animal functional foods.
Lei Zhuang, Yongbao Wu, Zitao Zhao, Junting Cao, Yanhong Guo, Zhanyue Wu, Qimeng Wang, Peilong Yang, Sen Wu, Zhiguo Wen, Shuisheng Hou   +10 more
wiley   +1 more source

Probiotic potential of Lactiplantibacillus plantarum LBK from Koumiss in reducing hyperuricemia through gut microbiota modulation

Frontiers in Microbiology
Hyperuricemia, a metabolic disorder resulting from purine metabolic dysfunction, poses a significant threat to public health. Probiotics, in particular lactic acid bacteria, have the potential to exert therapeutic benefits in the treatment of some ...
Panpan Zhao, Panpan Zhao, Panpan Zhao, Yibo Lu, Yibo Lu, Yibo Lu, Jianchun Xu, Jianchun Xu, Jianchun Xu, Hui Zhong, Hui Zhong, Hui Zhong, Qingqing Yan, Qingqing Yan, Qingqing Yan, Zhifeng Fang, Zhifeng Fang, Zhifeng Fang, Zhifeng Fang, Zhifeng Fang, Zhexin Fan, Zhexin Fan, Zhexin Fan, Zhexin Fan, Zhexin Fan, Qin Wang, Yuhui Li, Baokun Li, Baokun Li, Baokun Li, Baokun Li, Baokun Li, Xian Wang   +32 more
doaj   +1 more source

The power of many: when genetics met yeasts and high‐throughput

Biological Reviews, Volume 101, Issue 4, Page 1662-1682, August 2026.
ABSTRACT In recent years, complex technological capabilities have evolved, driven by the need to solve complex and integrative biological questions through global analyses. New equipment allows the scaling up and automation of processes which previously were carried out on a very limited scale.
Víctor A. Tallada, Víctor Carranco
wiley   +1 more source

Identification and characterization of hub genes underlying salt stress tolerance in rice (Oryza sativa L.)

Discover Plants
Salt-tolerant genes (STGs) play a crucial role in protecting rice against salt-induced stress. Hub genes (HGs), which are connected to other genes in the gene network, have also been found to encode regulators of biological processes that remained ...
Md. Atik Mas-ud, Sadiya Arefin Juthee, Yanchun Zhu, Aman Ullah, Nadeem Rujab, Md. Hosenuzzaman, Sabbir Ahmed, Mohammad Nurul Matin   +7 more
doaj   +1 more source

Familial hypercholesterolemia – Targeted whole gene sequencing as a diagnostic approach

Atherosclerosis Plus
Background and aims: Familial hypercholesterolemia (FH) and other disorders with similar features are common genetic disorders that remain underdiagnosed and undertreated, due in part to the cost of screening.
Emma Adolfsson, Nils Johan Fredriksson, Jon Jonasson, Anna Nordenskjöld, Anna Green   +4 more
doaj   +1 more source