Results 41 to 50 of about 60,219 (305)

ATP-binding cassette transporter 1 and Transglutaminase 2 act on the same genetic pathway in the apoptotic cell clearance [PDF]

Cell Death & Differentiation, 2006
ATP-binding cassette transporter 1 and Transglutaminase 2 act on the same genetic pathway in the apoptotic cell ...
Iadevaia, V., Rinaldi, A., Falasca, L., Pucillo, L. P., Alonzi, T., Chimini, G., Piacentini, M.   +6 more
openaire   +3 more sources

Conformational changes in the catalytically inactive nucleotide-binding site of CFTR. [PDF]

, 2013
A central step in the gating of the cystic fibrosis transmembrane conductance regulator (CFTR) chloride channel is the association of its two cytosolic nucleotide-binding domains (NBDs) into a head-to-tail dimer, with two nucleotides bound at the ...
Mihályi Csaba, Vergani P, Töröcsik, B, Csanády, László, Csanády László, Mihályi, C, Csaba Mihályi, Paola Vergani, Vergani, Paola, Beáta Töröcsik, Szollosi, A, László Csanády, Szőllősi, András, Szöllősi András, Törőcsik, Beáta, Mihályi, Csaba, Andras Szollosi, Vergani, P, Törőcsik Beáta, Csanády, L   +19 more
core   +1 more source

Structural and functional fingerprint of the mitochondrial ATP-binding cassette transporter Mdl1 from Saccharomyces cerevisiae

, 2021
The ATP-binding cassette half-transporter Mdl1 from Saccharomyces cerevisiae has been proposed to be involved in the quality control of misassembled respiratory chain complexes by exporting degradation products generated by the m-AAA proteases from the ...
Hofacker, Matthias, Tampé, Robert, Gompf, Simone, Haase, Winfried, Model, Kirstin, Presenti, Chiara, Zutz, Ariane, Does, Chris van der   +7 more
core   +2 more sources

A single high-dose irradiation changes accumulation of methotrexate and gene expression levels of SLC and ABC transporters in cancer cells

Frontiers in Pharmacology, 2023
Chemoradiotherapy is frequently used to treat cancer. Stereotactic body radiotherapy (SBRT) is a single high-dose radiotherapy used to treat a variety of cancers.
Kakeru Sato, Tatsuya Seki, Asuka Mizutani, Yuka Muranaka, Shiho Hirota, Kodai Nishi, Kana Yamazaki, Ryuichi Nishii, Takeo Nakanishi, Ikumi Tamai, Keiichi Kawai, Keiichi Kawai, Masato Kobayashi   +12 more
doaj   +1 more source

Influence of (ATP)-Binding Cassette Transporter Subfamily B Member 1 (ABCB1) Gene Polymorphism on the Efficacy of Remifentanil [PDF]

Medical Science Monitor, 2019
BACKGROUND The aim of this study was to investigate the influence of adenosine triphosphate (ATP)-binding cassette transporter subfamily B member 1 (ABCB1) gene polymorphism on the efficacy of Remifentanil. MATERIAL AND METHODS A total of 276 patients undergoing elective surgeries were included to collect general clinical information and detect the ...
Wang, Wenzhu, Zhou, Qinghua, Yuan, Changxiu   +2 more
openaire   +2 more sources

Therapeutic drugs modulate ATP-Binding cassette transporter-mediated transport of amyloid beta(1–42) in brain microvascular endothelial cells [PDF]

European Journal of Pharmacology, 2020
Deposition of amyloid-β peptide (Aβ(1-42)) is a hallmark of Alzheimer's disease. Clearance of Aβ(1-42), across the blood-brain barrier (BBB), is mediated by ATP-binding Cassette (ABC) efflux transporters. Many therapeutic drugs inhibit ABC transporters, but little is known of the effect of therapeutic drugs on Aβ(1-42) transport across BBB endothelial ...
Shubbar, Maryam, Penny, Jeffrey
openaire   +3 more sources

Amentoflavone-Enriched Selaginella rossii Warb. Suppresses Body Weight and Hyperglycemia by Inhibiting Intestinal Lipid Absorption in Mice Fed a High-Fat Diet

Life, 2022
Many Selaginellaceae species are used as traditional medicines in Asia. This study is the first to investigate the anti-obesity and anti-diabetic effects of Selaginella rossii (SR) in high-fat diet (HFD)–fed C57BL/6J mice.
Hwa Lee, Seona Cho, Soo-Yong Kim, Jeongha Ju, Sang Woo Lee, Sangho Choi, Hulin Li, Renzhe Piao, Ho-Yong Park, Tae-Sook Jeong   +9 more
doaj   +1 more source

Up-regulation of ATP-binding cassette transporters in the THP-1 human macrophage cell line by the antichagasic benznidazole [PDF]

Memórias do Instituto Oswaldo Cruz, 2016
تم تقييم تأثير البنزنيدازول (BZL) على تعبير ونشاط البروتين السكري P (P - gp، ABCB1) والبروتين المرتبط بمقاومة الأدوية المتعددة 2 (MRP2، ABCC2)، وهما الناقلان الرئيسيان للمركبات الداخلية والخارجية، في خلايا THP -1 المتمايزة. قام Bzl بتحفيز بروتينات P - gp و MRP2 بطريقة تعتمد على التركيز.
Virginia Perdomo, Juan Pablo Rigalli, Marcelo G. Luquita, José M Pellegrino, María Laura Ruiz, Viviana A. Catania   +5 more
openaire   +4 more sources

Inhibition of Mitogen-Activated Protein Kinase Erk1/2 Promotes Protein Degradation of ATP Binding Cassette Transporters A1 and G1 in CHO and in HuH7 cells.

, 2013
Signal transduction modulates expression and activity of cholesterol transporters. We recently demonstrated that the Ras/mitogen-activated protein kinase (MAPK) signaling cascade regulates protein stability of Scavenger Receptor BI (SR-BI) through ...
Enrich Bastús, Carles, Enrich Carlos, Karen Cecilia Chan, Monira Hoque, Darabi, Masoud, Reverter Martín, Meritxell, Hoque, Monira, Rentero Alfonso, Carles, Meritxell Reverter, Rentero Carles, Melanie Manetsch, Masoud Darabi, Mulay, Vishwaroop, Peta Wood, Grewal Thomas, Álvarez-Guaita, Anna, Heeren, Joerg, Anna Alvarez-Guaita, Kerry-Anne Rye, Darabi Masoud, Rye Kerry-Anne, Chan, Karen Cecilia, Manetsch, Melanie, Mulay Vishwaroop, Manetsch Melanie, Heeren Joerg, Carlos Enrich, Cairns, Rose, Reverter Meritxell, Joerg Heeren, Carles Rentero, Vishwaroop Mulay, Rose Cairns, Wood Peta, Wood, Peta, Grewal, Thomas, Rye, Kerry-Anne, Chan Karen Cecilia, Álvarez-Guaita Anna, Thomas Grewal, Hoque Monira, Cairns Rose   +41 more
core   +1 more source

Structure and Function of the Bacterial Heterodimeric ABC Transporter CydDC: Stimulation of the ATPase Activity by Thiol and Heme Compounds [PDF]

, 2014
In Escherichia coli, the biogenesis of both cytochrome bd-type quinol oxidases and periplasmic cytochromes requires the ABC- type cysteine/glutathione (GSH) transporter, CydDC.
Xie, H, Poole, Robert K,, Nyathi, Yvonne, Booth, WI, Nyathi, Y, Bullough, PA, Booth, Wesley I., Xie, Hua, Postis, Vincent; id_orcid, Poole, R. K., Tzokov, Svetomir B., Booth, W.I., Postis, Vincent, Yamashita, M., Booth, W. I., Baldwin, SA, Tzokov, S, Baldwin, Stephen A., Bullough, Per A, Postis, V, Postis, V., Yamashita, Masao, Yamashita, M, Bullough, Per A., Tzokov, Svetomir, Shepherd, M., Poole, RK, Bullough, P.A., Xie, Hao, Bullough, P. A., Poole, Robert K, Poole, R.K., Booth, Wesley I, Nyathi, Y., Tzokov, S. B., Xie, H., Baldwin, Stephen A, Baldwin, S.A., Tzokov, SB, Baldwin, S. A., Shepherd, Mark, Tzokov, S.B., Shepherd, M   +42 more
core   +1 more source