Patients homozygous for Tangier disease have a near absence of plasma HDL as a result of mutations in ABCA1 and hypercatabolize normal HDL particles. To determine the relationship between ABCA1 expression and HDL catabolism, we investigated intravascular
Ji-Young Lee +8 more
doaj +1 more source
Delivery of human apolipoprotein (apo) E to liver by an [E1(-), E3(-), polymerase(-), pTP(-)] adenovirus vector containing a liver-specific promoter inhibits atherogenesis in immunocompetent apoE-deficient mice [PDF]
Recombinant adenovirus (rAd)-mediated apoE gene transfer to the liver of apoE(-/-) mice is anti-atherogenic. However, first generation rAd vectors were associated with immune clearance of transduced hepatocytes, while an improved [E1(-), E3(-) polymerase(
Amalfitano, A +4 more
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Deficiency of ATP-Binding Cassette Transporters A1 and G1 in Macrophages Increases Inflammation and Accelerates Atherosclerosis in Mice [PDF]
Marit Westerterp +15 more
openalex +1 more source
Der Einfluss der Nikotinsäure auf die Expression von PPARgamma, Scavenger Rezeptoren und ABCA-1 auf monozytoiden und hepatischen Zellen [PDF]
Das natürliche Vitamin Nikotinsäure wird seit 1955 in pharmakologischer Dosierung als Medikament zur Behandlung von Dyslipidämien und bei arteriosklerotischen Gefäßveränderungen verwendet.
Trottmann, Matthias
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Intracellular cholesterol transporters and modulation of hepatic lipid metabolism: implications for diabetic dyslipidaemia and steatosis [PDF]
Caridis, Anna-Maria +3 more
core +1 more source
Physiologically regulated transgenic ABCA1 does not reduce amyloid burden or amyloid‐beta peptide levels in vivo [PDF]
J Lipid Res. 2007 Apr;48(4):914-23. Epub 2007 Jan 18. Physiologically regulated transgenic ABCA1 does not reduce amyloid burden or amyloid-beta peptide levels in vivo.
CHAN, J.Y. +9 more
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