Results 171 to 180 of about 12,429 (225)

Macrophage-activating lipopeptide-2 downregulates the expression of ATP-binding cassette transporter A1 by activating the TLR2/NF-кB/ZNF202 pathway in THP-1 macrophages.

Acta Biochim Biophys Sin (Shanghai), 2016
Peng L, Zhang Z, Zhang M, Yu X, Yao F, Tan Y, Liu D, Gong D, Chong H, Liu X, Zheng X, Tian G, Tang C.   +12 more
europepmc   +1 more source

Knowing Your ABCs

JACC: Basic to Translational Science
George A. Karpouzas, MD, Nicoletta Ronda, MD, PhD   +1 more
doaj   +1 more source

Comprehensive in silico characterization of proteins associated with light responses, transport, and stress-related processes in the gametophyte of the fern Dryopteris affinis ssp. affinis. [PDF]

BMC Genomics
Fernández H, Ojosnegros S, Álvarez JM, Vázquez F, Goya N, Quintanilla LG, Flexas J, Peña A, Grossniklaus U.   +8 more
europepmc   +1 more source

Current Understanding of Circulating Apolipoprotein E-Containing High-Density Lipoproteins and Their Clinical Utility in Cardiovascular Disease Risk Assessment. [PDF]

Yonago Acta Med
Usui S.
europepmc   +1 more source

Cholesterol-Inflammation Fusion Hypothesis in Atherosclerosis: An Evolving Paradigm in Pathogenesis and Therapy. [PDF]

JACC Asia
Zeng RX, Li S, Li JJ.
europepmc   +1 more source

Glycaemic Influences on the ATP-Binding Cassette Transporter A1 (ABCA1) [PDF]

, 2010
Increased glucose levels are associated with increased risk of vascular disease. The risk is elevated 2-4 fold in type 2 diabetes and there is a positive relationship between glucose (or HbA1c) levels and vascular disease in the general population. We tested the hypothesis that there is a glycaemia-mediated impairment of reverse cholesterol transport ...
Valabhji, Jonathan, Patel, Dipesh C, Johnston, Des   +2 more
core   +4 more sources

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Statins downregulate ATP-binding-cassette transporter A1 gene expression in macrophages

Biochemical and Biophysical Research Communications, 2004
The ATP-binding-cassette transporter A1 (ABCA1) plays an essential role in cellular cholesterol efflux and helps prevent macrophages from becoming foam cells. The statins are widely used as cholesterol-lowering agents and have other anti-atherogenic actions.
Hirohito Sone, Hitoshi Shimano, Masanori Nakakuki   +2 more
exaly   +3 more sources

Increased ATP-Binding Cassette Transporter A1 Expression in Alzheimer's Disease Hippocampal Neurons

Journal of Alzheimer's Disease, 2010
ATP-binding cassette transporter A1 (ABCA1) reduces amyloid-β burden in transgenic mouse models of Alzheimer's disease (AD). Associations between ABCA1 polymorphisms and AD risk are also established. Little is known regarding the regulation of ABCA1 expression in the brain and how this may be affected by AD.
Garner, Brett, McCann, H, Halliday, Glenda, Barnham, K J, Elliott, David, Kim, Woojin Scott, Agholme, Lotta, Kgedal, Katarina, Bhatia, Surabhi   +8 more
openaire   +4 more sources

Effects of Pravastatin on the Expression of ATP-Binding Cassette Transporter A1

The Journal of Pharmacology and Experimental Therapeutics, 2004
In vitro inhibition of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase causes the suppression of liver X receptor (LXR) activity. Because LXR regulates the expression of ATP-binding cassette transporter (ABC) A1, which is involved in the high-density lipoprotein-related reverse cholesterol transport pathway, we examined the effects of an HMG ...
Hitoshi, Ando, Shuichi, Tsuruoka, Hisashi, Yamamoto, Toshinari, Takamura, Shuichi, Kaneko, Akio, Fujimura   +5 more
openaire   +2 more sources