Results 21 to 30 of about 40,880 (280)

Association of ATP-Binding Cassette Transporter A1 Gene Polymorphisms in Type 2 Diabetes Mellitus among Malaysians [PDF]

Journal of Diabetes Research, 2015
Background. Type 2 diabetes mellitus (T2DM) is a complex polygenic disorder characterized by impaired insulin resistance, insulin secretion, and dysregulation of lipid and protein metabolism with environmental and genetic factors.
Polin Haghvirdizadeh, Vasudevan Ramachandran, Ali Etemad, Farzad Heidari, Nooshin Ghodsian, Norzian Bin Ismail, Patimah Ismail   +6 more
doaj   +2 more sources

A pan-cancer analysis targeting the oncogenic role of ATP-binding cassette transporter A1 in human tumors. [PDF]

Front Oncol
Wu H, Gu S, Xie S, Li X, Wang B, Liu Y, Huang Q.   +6 more
europepmc   +3 more sources

Lipid absorption defects in intestine-specific microsomal triglyceride transfer protein and ATP-binding cassette transporter A1-deficient mice. [PDF]

J Biol Chem, 2013
Background: The combined roles of intestinal MTP and ABCA1 in tissue and plasma lipid homeostasis are unknown. Results: Intestine-specific ablation of MTP and ABCA1 severely impairs acute fat and cholesterol absorption.
Iqbal J, Parks JS, Hussain MM.
europepmc   +2 more sources

Association of the ATP-Binding Cassette Transporter A1 R230C Variant With Early-Onset Type 2 Diabetes in a Mexican Population [PDF]

Diabetes, 2007
Teresa Villarreal‐Molina, María Teresa Flores-Dorantes, Olimpia Arellano‐Campos, Marisela Villalobos‐Comparán, Maricela Rodríguez‐Cruz, Ángel Miliar-García, Adriana Huertas‐Vázquez, Marta Menjívar, Sandra Romero‐Hidalgo, Niels H. Wacher, Marı́a Teresa Tusié-Luna, Miguel Cruz, Carlos A. Aguilar‐Salinas, Samuel Canizales‐Quinteros, the Metabolic Study Group   +14 more
openalex   +2 more sources

ATP-Binding Cassette Transporter A1 Modulates Apolipoprotein A-I Transcytosis Through Aortic Endothelial Cells [PDF]

Circulation Research, 2006
High-density lipoproteins and their major protein constituent apolipoprotein A-I (apoA-I) possess diverse atheroprotective properties. Most of them must be exerted within the arterial wall. Actually, high-density lipoproteins are the most abundant lipoproteins within the arterial intima.
Clara Cavelier, Lucia Rohrer, Arnold von Eckardstein   +2 more
openalex   +4 more sources

ATP-binding Cassette Transporter A1 (ABCA1) Functions as a Cholesterol Efflux Regulatory Protein* [PDF]

Journal of Biological Chemistry, 2001
ABCA1, an ATP-binding cassette transporter mutated in Tangier disease, promotes cellular phospholipid and cholesterol efflux by loading free apoA-I with these lipids. This process involves binding of apoA-I to the cell surface and phospholipid translocation by ABCA1.
Nan Wang, D. Silver, C. Thiele, A. Tall
semanticscholar   +3 more sources

Hydrogen Activates ATP-Binding Cassette Transporter A1-Dependent Efflux Ex Vivo and Improves High-Density Lipoprotein Function in Patients With Hypercholesterolemia: A Double-Blinded, Randomized, and Placebo-Controlled Trial [PDF]

Journal of Clinical Endocrinology and Metabolism, 2015
Guohua Song, Quanqiang Lin, Hui Zhao, Mei‐Yuan Liu, Fenglong Ye, Yujuan Sun, Yang Yu, Shoudong Guo, Peng Jiao, Yun Wu, Guoyong Ding, Qiang Xiao, Shucun Qin   +12 more
openalex   +2 more sources

The phosphatase activity of soluble epoxide hydrolase regulates ATP-binding cassette transporter-A1-dependent cholesterol efflux. [PDF]

J Cell Mol Med, 2019
Lien CC, Chen CH, Lee YM, Guo BC, Cheng LC, Pan CC, Shyue SK, Lee TS.   +7 more
europepmc   +3 more sources

Small GTPase ARF6 Regulates Endocytic Pathway Leading to Degradation of ATP-Binding Cassette Transporter A1. [PDF]

Arterioscler Thromb Vasc Biol, 2016
Mukhamedova N, Hoang A, Cui HL, Carmichael I, Fu Y, Bukrinsky M, Sviridov D.   +6 more
europepmc   +3 more sources

Effect of ATP-binding Cassette Transporter A1 (ABCA1) Gene Polymorphisms on Plasma Lipid Variables and Common Demographic Parameters in Greek Nurses. [PDF]

Open Cardiovasc Med J, 2016
Kolovou V, Marvaki A, Boutsikou M, Vasilopoulos G, Degiannis D, Marvaki C, Kolovou G.   +6 more
europepmc   +3 more sources