Results 31 to 40 of about 27,747 (231)

Atrial Natriuretic Peptide Inhibited ABCA1/G1-dependent Cholesterol Efflux Related to Low HDL-C in Hypertensive Pregnant Patients

Frontiers in Pharmacology, 2021
Objective: It has been reported that atrial natriuretic peptide (ANP) regulates lipid metabolism by stimulating adipocyte browning, lipolysis, and lipid oxidation, and by impacting the secretion of adipokines.
Yubing Dong, Yi Lin, Wanyu Liu, Wei Zhang, Yinong Jiang, Wei Song   +5 more
doaj   +1 more source

Increased ABCA1 (ATP-Binding Cassette Transporter A1)-Specific Cholesterol Efflux Capacity in Schizophrenia [PDF]

Arteriosclerosis, Thrombosis, and Vascular Biology, 2020
Objective: Patients with schizophrenia have increased long-term mortality attributable to cardiovascular disease and commonly demonstrate features of mixed dyslipidemia with low HDL-C (high-density lipoprotein cholesterol). The removal of cholesterol from cells by HDL via specific ATP-binding cholesterol transporters is a major
Luquain-Costaz, Céline, Kockx, Maaike, Anastasius, Malcolm, Chow, Vincent, Kontush, Anatol, Jessup, Wendy, Kritharides, Leonard   +6 more
openaire   +4 more sources

Phospholipid Transfer Protein Interacts with and Stabilizes ATP-binding Cassette Transporter A1 and Enhances Cholesterol Efflux from Cells*

Journal of Biological Chemistry, 2003
Phospholipid lipid transfer protein (PLTP) is ubiquitously expressed in animal tissues and plays multiple roles in lipoprotein metabolism, but the function of peripheral PLTP is still poorly understood.
J. Oram, G. Wolfbauer, A. Vaughan, Chongren Tang, J. Albers   +4 more
semanticscholar   +1 more source

ATP-binding cassette transporter A1 and HDL metabolism: effects of fatty acids [PDF]

The Journal of Nutritional Biochemistry, 2012
Ample evidence indicates that dietary fatty acids alter the plasma levels of high-density lipoprotein cholesterol (HDL-C). However, the mechanisms underlying the effects of fatty acids still remain elusive. Recent advances in our understanding of ATP-binding cassette transporter A1 (ABCA1) function and regulation have provided a valuable insight into ...
Jiyoung, Lee, Youngki, Park, Sung I, Koo
openaire   +2 more sources

Diabetes reduces the cholesterol exporter ABCA1 in mouse macrophages and kidneys1

Journal of Lipid Research, 2010
Accumulation of cholesterol in arterial macrophages may contribute to diabetes-accelerated atherosclerotic cardiovascular disease. The ATP-binding cassette transporter ABCA1 is a cardioprotective membrane protein that mediates cholesterol export from ...
Chongren Tang, Jenny E. Kanter, Karin E. Bornfeldt, Renee C. Leboeuf, John F. Oram   +4 more
doaj   +1 more source

ATP-binding Cassette Transporter A1 Expression Disrupts Raft Membrane Microdomains through Its ATPase-related Functions*

Journal of Biological Chemistry, 2006
ATP-binding cassette transporter A1 (ABCA1) is known to mediate cholesterol efflux to lipid-poor apolipoprotein A-I. In addition, ABCA1 has been shown to influence functions of the plasma membrane, such as endocytosis and phagocytosis.
Y. Landry, M. Denis, Shilpi Nandi, S. Bell, A. Vaughan, Xiaohui Zha   +5 more
semanticscholar   +1 more source

Helical Apolipoproteins Stabilize ATP-binding Cassette Transporter A1 by Protecting It from Thiol Protease-mediated Degradation*

Journal of Biological Chemistry, 2002
ATP-binding cassette transporter (ABC) A1 was increased by apolipoprotein A-I without an increase of its message in THP-1 cells. The pulse label study demonstrated that apoA-I retarded degradation of ABCA1.
R. Arakawa, S. Yokoyama
semanticscholar   +1 more source

Stanol esters decrease plasma cholesterol independently of intestinal ABC sterol transporters and Niemann-Pick C1-like 1 protein gene expression

Journal of Lipid Research, 2004
Possible mechanisms for the cholesterol-lowering effects of plant stanol esters were addressed by feeding hamsters diets containing stanol esters, cholesterol, or cholestyramine/lovastatin.
F. Jeffrey Field, Ella Born, Satya N. Mathur   +2 more
doaj   +1 more source

A novel enzyme immunoassay specific for ABCA1 protein quantification in human tissues and cells

Journal of Lipid Research, 2008
ATP-binding cassette transporter A1 (ABCA1) mediates the transport of cholesterol and phospholipids from cells to lipid-poor HDL and maintains cellular lipid homeostasis.
Vijay Paul, Heinrich H.D. Meyer, Katharina Leidl, Soni Soumian, Christiane Albrecht   +4 more
doaj   +1 more source

Regulation of ABCA1 expression and cholesterol efflux during adipose differentiation of 3T3-L1 cells

Journal of Lipid Research, 2003
Adipose cells specialized in energy storage, contain large intracellular triglyceride-rich lipid droplets, are enriched with free cholesterol, and express sterol-regulated transcription factors such as liver X receptor (LXR). The recent identification of
Soazig Le Lay, Céline Robichon, Xavier Le Liepvre, Georges Dagher, Pascal Ferre, Isabelle Dugail   +5 more
doaj   +1 more source