Results 31 to 40 of about 40,880 (280)

ATP-binding cassette transporter A1 expression is decreased in preeclamptic placentas. [PDF]

Reprod Sci, 2013
Preeclampsia is a pregnancy-specific multisystem disorder characterized by hypertension and proteinuria. Accentuated maternal hyperlipidemia, especially high serum levels of oxidized low-density lipoprotein (oxLDL), is one of the features of preeclampsia.
Chigusa Y, Kondoh E, Mogami H, Nishimura F, Ujita M, Kawasaki K, Fujita K, Tatsumi K, Konishi I.   +8 more
europepmc   +4 more sources

Modulation of microRNA Expression in Subjects with Metabolic Syndrome and Decrease of Cholesterol Efflux from Macrophages via microRNA-33-Mediated Attenuation of ATP-Binding Cassette Transporter A1 Expression by Statins. [PDF]

PLoS One, 2016
Chen WM, Sheu WH, Tseng PC, Lee TS, Lee WJ, Chang PJ, Chiang AN.   +6 more
europepmc   +3 more sources

Identification of dehydroxytrichostatin A as a novel up-regulator of the ATP-binding cassette transporter A1 (ABCA1). [PDF]

Molecules, 2011
Xu Y, Xu Y, Bao Y, Hong B, Si S.
europepmc   +3 more sources

ATP-binding cassette transporter A1 (ABCA1) affects total body sterol metabolism [PDF]

Gastroenterology, 2001
Members of the family of ABC transporters are involved in different processes of sterol metabolism, and ABCA1 was recently identified as a key regulator of high-density lipoprotein (HDL) metabolism. Our aim was to further analyze the role of ABCA1 in cholesterol metabolism.ABCA1-deficient mice (ABCA1-/-) and wild-type mice were compared for different ...
Wolfgang Drobnik, B. Lindenthal, Bernd Lieser, Mirko Ritter, Trudy Christiansen Weber, Gerhard Liebisch, Uwe Giesa, Michael Igel, Hana Borsukova, Christa Büchler, Wai‐Ping Fung‐Leung, Klaus von Bergmann, Gerd Schmitz   +12 more
openalex   +3 more sources

ATP-binding cassette transporter A1: A promising therapy target for prostate cancer. [PDF]

Mol Clin Oncol, 2018
ATP-binding cassette transporter A1 (ABCA1) has been found to mediate the transfer of cellular cholesterol across the plasma membrane to apolipoprotein A-I (apoA-I), and is essential for the synthesis of high-density lipoprotein. Mutations of the ABCA1 gene may induce Tangier disease and familial hypoalphalipoproteinemia; they may also lead to loss of ...
Xiong T, Xu G, Huang XL, Lu KQ, Xie WQ, Yin K, Tu J.   +6 more
europepmc   +4 more sources

Association of ATP-Binding Cassette Transporter A1 (ABCA1)-565 C/T Gene Polymorphism with Hypoalphalipoproteinemia and Serum Lipids, IL-6 and CRP Levels. [PDF]

Avicenna J Med Biotechnol, 2017
Babashamsi MM, Halalkhor S, Moradi Firouzjah H, Parsian H, Jalali SF, Babashamsi M.   +5 more
europepmc   +2 more sources

ATP-binding cassette transporter A1 is significantly involved in the intestinal absorption of α- and γ-tocopherol but not in that of retinyl palmitate in mice

American Journal of Clinical Nutrition, 2008
Emmanuelle Reboul, Doriane Trompier, Myriam Moussa, Alexis Klein, Jean‐François Landrier, Giovanna Chimini, Patrick Borel   +6 more
openalex   +3 more sources

ABCA1 is an extracellular phospholipid translocase

Nature Communications, 2022
ATP-binding cassette transporter A1 (ABCA1) drives phospholipid (PL) from the plasma membrane into extracellular apolipoprotein A-I, for the production of high density lipoprotein (HDL).
Jere P. Segrest, Chongren Tang, Hyun D. Song, Martin K. Jones, W. Sean Davidson, Stephen G. Aller, Jay W. Heinecke   +6 more
doaj   +1 more source

Apolipoprotein A1-Related Proteins and Reverse Cholesterol Transport in Antiatherosclerosis Therapy: Recent Progress and Future Perspectives

Cardiovascular Therapeutics, 2022
Hyperlipidemia characterized by abnormal deposition of cholesterol in arteries can cause atherosclerosis and coronary artery occlusion, leading to atherosclerotic coronary heart disease.
Xiuting Xu, Zikai Song, Bao Mao, Guoliang Xu   +3 more
doaj   +1 more source

Chalcone Derivatives Enhance ATP-Binding Cassette Transporters A1 in Human THP-1 Macrophages [PDF]

Molecules, 2018
Atherosclerosis is a process of imbalanced lipid metabolism in the vascular walls. The underlying pathology mainly involves the deposition of oxidized lipids in the endothelium and the accumulation of cholesterol in macrophages. Macrophages export excessive cholesterol (cholesterol efflux) through ATP-binding cassette transporter A1 (ABCA1) to counter ...
I-Jou Teng, Min‐Chien Tsai, Shao-Fu Shih, Bi-Feng Tsuei, Hsin Wen Chang, Yi‐Ping Chuang, Chin‐Sheng Lin, Ching‐Yuh Chern, Sy‐Jou Chen   +8 more
openalex   +5 more sources